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Cardenolides

Known as: Cardenolides [Chemical/Ingredient], cardenolide 
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

10beta-hydroxy-19-nor-cardenolide12-dehydroxyghalakinoside19-hydroxysarmentogenin6'-dehydroxyghalakinoside

Broader (1)

Cardanolides
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2013
Highly Cited
2013
STEPWISE EVOLUTION OF RESISTANCE TO TOXIC CARDENOLIDES VIA GENETIC SUBSTITUTIONS IN THE NA+/K+‐ATPASE OF MILKWEED BUTTERFLIES (LEPIDOPTERA: DANAINI)
Despite the monarch butterfly (Danaus plexippus) being famous for its adaptations to the defensive traits of its milkweed host… 
Review
2012
Review
2012
Toxic cardenolides: chemical ecology and coevolution of specialized plant-herbivore interactions.
Cardenolides are remarkable steroidal toxins that have become model systems, critical in the development of theories for chemical… 
Highly Cited
2012
Highly Cited
2012
Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase
The extent of convergent molecular evolution is largely unknown, yet is critical to understanding the genetics of adaptation… 
Highly Cited
2012
Highly Cited
2012
Adaptive geographical clines in the growth and defense of a native plant
Broad-scale geographical gradients in the abiotic environment and interspecific interactions should select for clinal adaptation… 
Review
2007
Review
2007
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth.
Cardiotonic steroids (CTS), long used to treat heart failure, are endogenously produced in mammals. Among them are the… 
Review
2002
Review
2002
Endogenous cardiac glycosides, a new class of steroid hormones.
The search for endogenous digitalis has led to the isolation of ouabain as well as several additional cardiotonic steroids of the… 
Review
2001
Review
2001
Chromatographic procedures for the isolation of plant steroids.
Highly Cited
1999
Highly Cited
1999
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.
OBJECTIVE To determine plasma levels of the endogenous bufodienolide Na+/K+ ATPase inhibitor, marinobufagenin-like factor (MBG… 
Highly Cited
1991
Highly Cited
1991
Corrections and Retraction: Identification and Characterization of a Ouabain-Like Compound from Human Plasma
Highly Cited
1970
Highly Cited
1970
On the reversibility of binding of cardiotonic steroids to a partially purified (Na+K)-activated adenosinetriphosphatase from beef brain.
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