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Cardenolides

Known as: Cardenolides [Chemical/Ingredient], cardenolide 
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

10beta-hydroxy-19-nor-cardenolide12-dehydroxyghalakinoside19-hydroxysarmentogenin6'-dehydroxyghalakinoside

Broader (1)

Cardanolides
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2008
Highly Cited
2008
Coexisting congeners: demography, competition, and interactions with cardenolides for two milkweed‐feeding aphids
Explaining the coexistence of closely related species sharing a single resource has been a long-standing challenge in ecology… 
Highly Cited
2006
Highly Cited
2006
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.
Non-small cell lung cancers (NSCLCs) are the leading cause of cancer deaths in most developed countries. Targeting heat shock… 
Highly Cited
2004
Highly Cited
2004
Density-Dependent Reduction and Induction of Milkweed Cardenolides by a Sucking Insect Herbivore
The effect of aphid population size on host-plant chemicalDefense expression and the effect of plantDefense on aphid population… 
2000
2000
Poisoned plusiines: toxicity of milkweed latex and cardenolides to some generalist caterpillars
Summary. Larvae of Trichoplusia ni Hübner (Lepidoptera: Noctuidae) that ingested latex from Asclepias curassavica L… 
Highly Cited
1998
Highly Cited
1998
The Inhibition of Fibroblast Growth Factor-2 Export by Cardenolides Implies a Novel Function for the Catalytic Subunit of Na+,K+-ATPase*
Basic fibroblast growth factor (FGF-2) is one of a select group of proteins that can exit cells through an alternate, endoplasmic… 
Review
1991
Review
1991
The digoxigenin:anti-digoxigenin (DIG) technology--a survey on the concept and realization of a novel bioanalytical indicator system.
Highly Cited
1990
Highly Cited
1990
Non-radioactive labeling and detection of nucleic acids. I. A novel DNA labeling and detection system based on digoxigenin: anti-digoxigenin ELISA principle (digoxigenin system).
A novel highly sensitive non-radioactive DNA labeling and detection system based on the ELISA principle has been developed. DNA… 
Highly Cited
1986
Highly Cited
1986
Origin of differences of inhibitory potency of cardiac glycosides in Na+/K+-transporting ATPase from human cardiac muscle, human brain cortex and guinea-pig cardiac muscle.
Highly Cited
1970
Highly Cited
1970
On the reversibility of binding of cardiotonic steroids to a partially purified (Na+K)-activated adenosinetriphosphatase from beef brain.
1966
1966
The synthesis of digitoxigenin.
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