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Cardenolides

Known as: Cardenolides [Chemical/Ingredient], cardenolide 
C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must… Expand
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

10beta-hydroxy-19-nor-cardenolide12-dehydroxyghalakinoside19-hydroxysarmentogenin6'-dehydroxyghalakinoside
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Broader (1)

Cardanolides
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Toxic cardenolides: chemical ecology and coevolution of specialized plant-herbivore interactions.
Cardenolides are remarkable steroidal toxins that have become model systems, critical in the development of theories for chemical… Expand
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Highly Cited
2012
Highly Cited
2012
Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase
The extent of convergent molecular evolution is largely unknown, yet is critical to understanding the genetics of adaptation… Expand
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Highly Cited
2011
Highly Cited
2011
Latitudinal patterns in plant defense: evolution of cardenolides, their toxicity and induction following herbivory.
Attempts over the past 50 years to explain variation in the abundance, distribution and diversity of plant secondary compounds… Expand
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Review
2011
Review
2011
Coping with toxic plant compounds--the insect's perspective on iridoid glycosides and cardenolides.
Specializing on host plants with toxic secondary compounds enforces specific adaptation in insect herbivores. In this review, we… Expand
Review
2009
Review
2009
Endogenous Cardiotonic Steroids: Physiology, Pharmacology, and Novel Therapeutic Targets
Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been postulated to play important roles in health… Expand
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Review
2008
Review
2008
Why Does Herbivore Attack Reconfigure Primary Metabolism?
A plant's resistance to herbivore attack is thought to be principally determined by its secondary metabolism, which can be… Expand
Review
2002
Review
2002
Endogenous cardiac glycosides, a new class of steroid hormones.
  • W. Schoner
  • European journal of biochemistry
  • 2002
    • Corpus ID: 23319401
The search for endogenous digitalis has led to the isolation of ouabain as well as several additional cardiotonic steroids of the… Expand
Highly Cited
1999
Highly Cited
1999
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.
OBJECTIVE To determine plasma levels of the endogenous bufodienolide Na+/K+ ATPase inhibitor, marinobufagenin-like factor (MBG… Expand
Highly Cited
1991
Highly Cited
1991
Identification and characterization of a ouabain-like compound from human plasma.
The plasma membrane sodium-potassium pumps that regulate intracellular sodium in most animal cells have specific, high-affinity… Expand
Highly Cited
1981
Highly Cited
1981
Birds can overcome the cardenolide defence of monarch butterflies in Mexico
Flocks of black-backed orioles (Icterus abeillei Lesson) and black-headed grosbeaks (Pheucticus melanocephalus Swainson) eat… Expand
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