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Antileukemic Agent

Any substance that treats, prevents, or inhibits the development of leukemia.
National Institutes of Health

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Broader (1)

Antineoplastic Agents

Papers overview

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2006
2006
The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines.
Highly Cited
2002
Highly Cited
2002
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia…
PURPOSE The purpose of the study is to investigate the tolerability of interleukin 2 (IL-2) after intensive chemotherapy in… 
Highly Cited
2002
Highly Cited
2002
Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia
IL12 is an essential cytokine for the generation of T helper 1 response, natural killer (NK) cells and cytotoxic T lymphocyte… 
Review
1994
Review
1994
Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy.
Review
1990
Review
1990
Biochemical modulation of cytosine arabinoside.
Highly Cited
1988
Highly Cited
1988
Functional consequences of the arabinosylcytosine structural lesion in DNA.
Cytosine arabinoside (araC) is a potent antileukemic agent that is misincorporated into DNA in the course of its action. We have… 
Highly Cited
1983
Highly Cited
1983
Interaction of the antileukemic alkaloid, 2-hydroxy-3,8,9-trimethoxy-5-methylbenzo[c]phenanthridine (fagaronine), with nucleic acids.
1980
1980
Comparison of the immunosuppressive effects of asparaginases from Escherichia coli and Vibrio succinogenes.
Abstract The immunosuppressive effects of antileukemic asparaginases isolated from Escherichia coli and Erwinia carotovora are… 
Highly Cited
1968
Highly Cited
1968
The carcinostatic activity of 5-hydroxy-2-formylpyridine thiosemicarbazone.
5-Hydroxy-2-formylpyridine thiosemicarbazone (5-HP) is highly active intraperitoneally against leukemia L-1210, Ehrlich ascites… 
1955
1955
Factors influencing the specificity of action of an antileukemic agent (aminopterin); multiple treatment schedules plus delayed administration of citrovorum factor.
Summary Multiple treatment with aminopterin and the administration of CF subsequent to treatment with aminopterin both increase… 
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