Angiotensin II

Known as: angiotensin 2, Angiotensin II [Chemical/Ingredient], 2 angiotensin 
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal… (More)
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (11)

(6-biotinylamido)hexanoylangiotensin IIDD 3487angiotensin II (1-8)angiotensin II (3-7)
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AGT geneAngiotensin II:SCnc:Pt:Plas:QnAngiotensin II^supine:MCnc:Pt:Plas:QnAngiotensin II^upright:SCnc:Pt:Plas:Qn
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Broader (2)

AngiotensinsVasoconstrictor Agents

Papers overview

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Highly Cited
2007
Highly Cited
2007
Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction
Hypertension promotes atherosclerosis and is a major source of morbidity and mortality. We show that mice lacking T and B cells… (More)
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Highly Cited
2002
Highly Cited
2002
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin.
Renin is an aspartyl protease essential for the control of blood pressure and was long suspected to have cellular receptors. We… (More)
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Review
2000
Review
2000
International union of pharmacology. XXIII. The angiotensin II receptors.
The cardiovascular and other actions of angiotensin II (Ang II) are mediated by AT(1) and AT(2) receptors, which are seven… (More)
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Review
2000
Review
2000
Adipose Tissue as an Endocrine Organ
The discovery of leptin in the mid-1990s has focused attention on the role of proteins secreted by adipose tissue. Leptin has… (More)
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Highly Cited
2000
Highly Cited
2000
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice.
Increased plasma concentrations of angiotension II (Ang II) have been implicated in atherogenesis. To examine this relationship… (More)
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Review
2000
Review
2000
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.
Until recently, the signaling events elicited in vascular smooth muscle cells by angiotensin II (Ang II) were considered to be… (More)
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Highly Cited
1997
Highly Cited
1997
Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension.
BACKGROUND The major source of superoxide (.O2-) in vascular tissues is an NADH/NADPH-dependent, membrane-bound oxidase. We have… (More)
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Highly Cited
1996
Highly Cited
1996
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
We tested the hypothesis that angiotensin II-induced hypertension is associated with an increase in vascular .O2- production, and… (More)
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Highly Cited
1994
Highly Cited
1994
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are… (More)
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Highly Cited
1993
Highly Cited
1993
Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.
Increasing evidence suggests that angiotensin II (Ang II) may act as a growth factor for the heart. However, direct effects of… (More)
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