AGT gene

Known as: alpha-1 antiproteinase, antitrypsin, ANGIOTENSINOGEN, Angiotensinogen (Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 8) Gene 
This gene plays a critical role in blood pressure maintenance and in the pathogenesis of essential hypertension and preeclampsia.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Adipose tissue represents an important source of angiotensinogen (AGT). We investigated the effect of obesity induced by a high… (More)
  • table 1
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
2002
2002
Previous studies have suggested that angiotensinogen (AGT) gene variants are associated with increased plasma AGT levels, and may… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
2002
2002
BACKGROUND The extent to which genes modify the relationship between risk factors for hypertension and blood pressure (BP) is… (More)
Is this relevant?
1999
1999
We made use of targeted disruption of the mouse angiotensinogen (ATN) gene to examine the functional role of the ATN in the… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The renin-angiotensin-aldosterone system plays an important role in blood pressure regulation by influencing salt-water… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
We tested the hypothesis that the tissue-specific intrarenal renin-angiotensin system (RAS) can participate in the regulation of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The M235T polymorphism of the angiotensinogen gene (AGT) has been associated with essential and pregnancy-induced hypertension… (More)
Is this relevant?
1997
1997
Genetic variability in the renin-angiotensin system may modify renal responses to injury and disease progression. We examined… (More)
  • table I
  • figure 1
  • table II
  • figure 2
  • table III
Is this relevant?
Highly Cited
1994
Highly Cited
1994
BACKGROUND The renin-angiotensin system is a powerful pressor system with a major influence on salt and water homeostasis… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
A reaction between enzyme renin and its only natural substrate angiotensinogen is the initial and rate-limiting step for… (More)
Is this relevant?