Angiotensin II Receptor, Type 2

Known as: Angiotensin II Type-2 Receptor, Angiotensin AT2 Receptor, Receptor, Angiotensin AT2 
An angiotensin receptor subtype that is expressed at high levels in fetal tissues. Many effects of the angiotensin type 2 receptor such as… (More)
National Institutes of Health

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25 relations
AGTR2 geneAGTR2 wt AlleleAdrenal GlandsAngiotensin-converting Enzyme 2 Pathway
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Papers overview

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Highly Cited
2001
Highly Cited
2001
Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension.
BACKGROUND The roles of angiotensin II (Ang II) in the regulation of heart function under normal and pathological conditions have… (More)
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Highly Cited
2001
Highly Cited
2001
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury.
BACKGROUND To investigate the effect of angiotensin (Ang) II type 1 receptor (AT(1)) blocker on vascular remodeling and explore… (More)
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Review
2000
Review
2000
International union of pharmacology. XXIII. The angiotensin II receptors.
The cardiovascular and other actions of angiotensin II (Ang II) are mediated by AT(1) and AT(2) receptors, which are seven… (More)
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Highly Cited
2000
Highly Cited
2000
Evidence for angiotensin II type 2 receptor-mediated cardiac myocyte enlargement during in vivo pressure overload.
The pathophysiological roles of the angiotensin II type 2 receptor (AT(2)) in cardiac hypertrophy remain unclear. By the targeted… (More)
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Highly Cited
1999
Highly Cited
1999
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.
Angiotensin II (Ang II) is a potent vasopressor peptide that interacts with 2 major receptor isoforms - AT1 and AT2. Although… (More)
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Highly Cited
1997
Highly Cited
1997
The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.
The angiotensin AT2 receptor modulates renal production of cyclic guanosine 3',5'-monophosphate (cGMP; J. Clin. Invest. 1996. 97… (More)
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Highly Cited
1997
Highly Cited
1997
Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.
Glomerular influx of monocytes/macrophages (M/M) occurs in many immune- and non-immune-mediated renal diseases. The mechanisms… (More)
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Highly Cited
1996
Highly Cited
1996
Role of type 1 and type 2 angiotensin receptors in angiotensin II-induced cardiomyocyte hypertrophy.
We compared the ability of angiotensin II (Ang II) to induce hypertrophy of neonatal rat ventricular myocytes with that of… (More)
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Highly Cited
1995
Highly Cited
1995
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice
ANGIOTENSIN II, a potent regulator of blood pressure and of water and electrolyte balance, binds to two different G-protein… (More)
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Highly Cited
1995
Highly Cited
1995
Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor
THERE are two major angiotensin II receptor isoforms, AT1 and AT2. AT1 mediates the well-known pressor and mitogenic effects of… (More)
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