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Angiostatins

Known as: ANGIOSTATIN, Angiostatins [Chemical/Ingredient] 
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Angiogenesis InhibitorsAntineoplastic AgentsPlasminogen
AngiostatIn BloodPLG geneProcess of secretion

Narrower (1)

angiostatin, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue.
2006
2006
PEDF: bridging neurovascular interactions in the stem cell niche
Stem cells are defined by their ability to self-renew. Adult brain stem cells divide slowly, and it is unclear how their division… 
Highly Cited
2003
Highly Cited
2003
Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model
Ischemic retinal diseases, such as diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration, are a… 
2003
2003
Antiangiogenic therapy against experimental glioblastoma using genetically engineered cells producing interferon-alpha, angiostatin, or endostatin.
Inhibition of angiogenesis has been considered among the most promising approaches to treat highly vascularized solid tumors such… 
2003
2003
Long‐term expression of angiostatin suppresses metastatic liver cancer in mice
Metastatic liver cancer has a very poor prognosis and lacks effective therapy. Anti‐angiogenic therapies, which starve tumors of… 
Highly Cited
2002
Highly Cited
2002
Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis.
OBJECTIVE To determine the efficacy of local therapy with human angiostatin gene in murine collagen-induced arthritis (CIA… 
Highly Cited
2000
Highly Cited
2000
Release of the angiogenesis inhibitor angiostatin in patients with proliferative diabetic retinopathy: association with retinal photocoagulation
Aims/hypothesis. Proliferative diabetic retinopathy is a major debilitating disease causing most cases of blindness in humans in… 
Review
1999
Review
1999
Therapeutic potentials of angiostatin in the treatment of cancer.
The discovery of specific endothelial inhibitors such as angiostatin and endostatin not only increases our understanding of the… 
Highly Cited
1998
Highly Cited
1998
Angiostatin-mediated Suppression of Cancer Metastases by Primary Neoplasms Engineered to Produce Granulocyte/Macrophage Colony–stimulating Factor
We determined whether tumor cells consistently generating granulocyte/macrophage colony– stimulating factor (GM-CSF) can recruit… 
1998
1998
Evaluation of the balance between angiogenic and antiangiogenic circulating factors in patients with breast and gastrointestinal cancers.
Angiogenesis is a critical determinant of tumor growth. Tumor cells produce or induce angiogenic molecules that act specifically… 
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