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Angiostatins

Known as: ANGIOSTATIN, Angiostatins [Chemical/Ingredient] 
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Angiogenesis InhibitorsAntineoplastic AgentsPlasminogen
AngiostatIn BloodPLG geneProcess of secretion

Narrower (1)

angiostatin, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism.
Angiostatin, a proteolytic fragment of plasminogen, is a potent anti-angiogenic factor recently shown also to have an inhibitory… 
Highly Cited
2006
Highly Cited
2006
Angiostatin decreases cell migration and vascular endothelium growth factor (VEGF) to pigment epithelium derived factor (PEDF) RNA ratio in vitro and in a murine ocular melanoma model.
PURPOSE Our previous experiments have shown that low dose angiostatin results in decreased hepatic micrometastasis in a mouse… 
2004
2004
Stent-based controlled release of intravascular angiostatin to limit plaque progression and in-stent restenosis.
PURPOSE To evaluate the importance of angiogenesis in plaque progression after stent placement, this study examines stent-based… 
2002
2002
Angiostatin induces intracellular acidosis and anoikis in endothelial cells at a tumor-like low pH.
Angiostatin inhibits angiogenesis by binding to endothelial cells (ECs) lining the vasculature of growing tumors. These cells are… 
Review
2001
Review
2001
Angiogenin and Its Functions in Angiogenesis
The review is devoted to angiogenin, one of the factors that induce formation of blood vessels, which is unique in that it is a… 
2001
2001
Effect of external ocular surgery and mode of post-operative care on plasminogen, plasmin, angiostatins and a2-macroglobulin in tears
Purpose. To determine whether corneal surgery and the mode of post-surgical treatment influence the distribution of plasminogen… 
2001
2001
Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy
The effect of local and systemic delivery of the angiostatin gene on human melanoma growth was studied in nude mice. Liposome… 
2000
2000
Outpatient pharmaceuticals and the elderly: policies in seven nations.
1999
1999
Angiostatin's Partners
I am writing to comment on Marcia Barinaga's article “A surprising partner for angiostatin” (News of the Week, 19 Mar. p. [1831… 
1998
1998
Angiostatin generation by human pancreatic cancer.
BACKGROUND Angiostatin, a proteolytic fragment of plasminogen, is a potent inhibitor of angiogenesis. In vitro, angiostatin can… 
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