Skip to search formSkip to main contentSkip to account menu

PLG gene

Known as: Plasminogen Gene, PLASMINOGEN, MICROPLASMIN 
This gene is involved in blood coagulation/hemostasis. It also plays a role in embryonic development, tissue remodeling and inflammation.
National Institutes of Health

Related topics

Related topics

9 relations
Angiogenic ProcessAngiostatinsHydrolysisMetastasis Suppression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds.
Despite decades of research on wound healing, effective biologic agents for the treatment of chronic wounds, especially diabetic… 
Highly Cited
2007
Highly Cited
2007
MICROPLASMIN-INDUCED POSTERIOR VITREOUS DETACHMENT AFFECTS VITREOUS OXYGEN LEVELS
Purpose: To determine if enzymatic induction of a posterior vitreous detachment (PVD) and/or vitreous liquefaction affects O2… 
Highly Cited
2003
Highly Cited
2003
A functional overlap of plasminogen and MMPs regulates vascularization during placental development
Both plasminogen activators and matrix metalloproteinases (MMPs) have been implicated in a variety of developmental processes in… 
Review
2000
Review
2000
Molecular mechanisms of plasminogen activation: bacterial cofactors provide clues.
Highly Cited
1999
Highly Cited
1999
Angiostatin Formation Involves Disulfide Bond Reduction and Proteolysis in Kringle 5 of Plasmin*
Plasmin is processed in the conditioned medium of HT1080 fibrosarcoma cells producing fragments with the domain structures of the… 
Highly Cited
1997
Highly Cited
1997
Homozygous Type I Plasminogen Deficiency
Homozygous type I plasminogen (Plg) deficiency has not been described in human subjects so far. Ligneous conjunctivitis is a rare… 
Review
1994
Review
1994
Lp(a) lipoprotein: an overview.
Highly Cited
1994
Highly Cited
1994
Cell-surface plasminogen activation causes a retraction of in vitro cultured human umbilical vein endothelial cell monolayer.
Vascular endothelium forms a dynamic interface between blood and underlying tissues. Endothelial monolayer integrity is required… 
Highly Cited
1991
Highly Cited
1991
The endothelial cell tissue plasminogen activator receptor. Specific interaction with plasminogen.
Highly Cited
1984
Highly Cited
1984
Complex formation of platelet thrombospondin with plasminogen. Modulation of activation by tissue activator.
Thrombospondin (TSP), a multifunctional alpha-granule glycoprotein of platelets, binds fibrinogen, fibronectin, heparin, and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)