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The aim of this updated guideline is to provide comprehensive and timely evidence-based recommendations on the prevention of… Expand It has recently been demonstrated that mouse and human fibroblasts can be reprogrammed into an embryonic stem cell–like state by… Expand Preface 7. Microbiological tests 7.1 Microbiology practice and quality assurance in district laboratories 7.2 Features and… Expand BACKGROUND
Blood transfusions prevent recurrent stroke in children with sickle cell anemia, but the value of transfusions in… Expand Cerebrovascular accident (CVA) is a major complication of sickle cell disease. The incidence and mortality of and risk factors… Expand BACKGROUND
In a previous open-label study of hydroxyurea therapy, the synthesis of fetal hemoglobin increased in most patients… Expand BACKGROUND
Information on life expectancy and risk factors for early death among patients with sickle cell disease (sickle cell… Expand BACKGROUND AND METHODS
Acute episodes of pain are the principal symptom of sickle cell disease, but little is known about the… Expand Children with sickle cell anemia have an increased susceptibility to bacterial infections, especially to those caused by… Expand Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first… Expand