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Anemia, Sickle Cell
Known as:
Cell Diseases, Sickle
, Cell Disorders, Sickle
, Hemoglobin SS Disease
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An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red…
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National Institutes of Health
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Related topics
Related topics
41 relations
0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe
Abdominal Pain
Acute Chest Syndrome
Alprostadil
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Broader (6)
Anemia
Anemia, Hemolytic
Anemia, Hemolytic, Congenital
Hematological Disease
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Narrower (2)
Hemoglobin SC Disease
Hemoglobin SS disease with crisis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results.
Margaret T. Lee
,
S. Piomelli
,
+4 authors
R. Adams
Blood
2006
Corpus ID: 17416767
The Stroke Prevention Trial in Sickle Cell Anemia (STOP) was a randomized trial to evaluate whether chronic transfusion could…
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Review
2005
Review
2005
Control of globin gene expression during development and erythroid differentiation.
G. Stamatoyannopoulos
Experimental Hematology
2005
Corpus ID: 1481232
Highly Cited
2003
Highly Cited
2003
Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes.
A. Shet
,
O. Aras
,
+6 authors
R. Hebbel
Blood
2003
Corpus ID: 6530143
Blood microparticles (MPs) in sickle cell disease (SCD) are reportedly derived only from erythrocytes and platelets. Yet in SCD…
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Highly Cited
2001
Highly Cited
2001
Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease.
Scott T. Miller
,
E. Macklin
,
+15 authors
M. DeBaun
Jornal de Pediatria
2001
Corpus ID: 40547119
OBJECTIVE To determine whether children with homozygous sickle cell anemia (SCD) who have silent infarcts on magnetic resonance…
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Highly Cited
2000
Highly Cited
2000
Multicenter Prospective Study of Children With Sickle Cell Disease: Radiographic and Psychometric Correlation
Françoise Bernaudin
,
S. Verlhac
,
+21 authors
P. Brugières
Journal of Child Neurology
2000
Corpus ID: 25470082
After obtaining familial informed consent, between January 1996 and July 1997, 173 children (5 to 15 years old) with sickle cell…
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Highly Cited
1996
Highly Cited
1996
Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flow-cytometric measurement and clinical associations.
B. Wood
,
D. Gibson
,
J. Tait
Blood
1996
Corpus ID: 19567754
Increased exposure of phosphatidylserine (PS) in erythrocytes has been postulated to contribute to the pathophysiology of sickle…
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Review
1990
Review
1990
Sickle cell hemoglobin polymerization.
W. Eaton
,
J. Hofrichter
Advances in Protein Chemistry
1990
Corpus ID: 5470555
Highly Cited
1984
Highly Cited
1984
Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
O. Platt
,
Stuart H. Orkin
,
G. Dover
,
G. Beardsley
,
B. Miller
,
D. G. Nathan
Journal of Clinical Investigation
1984
Corpus ID: 8133047
Hydroxyurea, a widely used cytotoxic/cytostatic agent that does not influence methylation of DNA bases, increases fetal…
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Highly Cited
1984
Highly Cited
1984
Bone-marrow transplantation in a patient with sickle-cell anemia.
F. Johnson
,
A. Look
,
J. Gockerman
,
M. Ruggiero
,
L. Dalla-Pozza
,
F. Billings
New England Journal of Medicine
1984
Corpus ID: 9162830
SICKLE-CELL anemia affects 1 in 600 of the U.S. black population and accounts for 80,000 deaths annually throughout the world.1…
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Highly Cited
1983
Highly Cited
1983
Erythrocytes in sickle cell anemia are heterogeneous in their rheological and hemodynamic characteristics.
D. Kaul
,
M. Fabry
,
P. Windisch
,
S. Baez
,
R. Nagel
Journal of Clinical Investigation
1983
Corpus ID: 30102365
To understand the contribution to the pathophysiology of sickle cell anemia of the different erythrocyte density types present in…
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