Anemia, Sickle Cell

Known as: Cell Diseases, Sickle, Cell Disorders, Sickle, Hemoglobin SS Disease 
An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
It has recently been demonstrated that mouse and human fibroblasts can be reprogrammed into an embryonic stem cell-like state by… (More)
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Review
2007
Review
2007
Hemolysis, long discounted as a critical measure of sickle cell disease severity when compared with sickle vaso-occlusion, may be… (More)
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Highly Cited
1998
Highly Cited
1998
Cerebrovascular accident (CVA) is a major complication of sickle cell disease. The incidence and mortality of and risk factors… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Blood transfusions prevent recurrent stroke in children with sickle cell anemia, but the value of transfusions in… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The vascular wall participates in the pathogenesis of sickle cell disease. To determine whether the endothelium is… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND In a previous open-label study of hydroxyurea therapy, the synthesis of fetal hemoglobin increased in most patients… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND Information on life expectancy and risk factors for early death among patients with sickle cell disease (sickle cell… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Acute episodes of pain are the principal symptom of sickle cell disease, but little is known about the… (More)
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Highly Cited
1986
Highly Cited
1986
Children with sickle cell anemia have an increased susceptibility to bacterial infections, especially to those caused by… (More)
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Highly Cited
1985
Highly Cited
1985
Two new methods were used to establish a rapid and highly sensitive prenatal diagnostic test for sickle cell anemia. The first… (More)
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