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Alprostadil

Known as: Alprostadilum, PGE1, Lipo PGE1 
The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that… Expand
National Institutes of Health

Related topics

Related topics

45 relations
0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe [Caverject]1 ML Alprostadil 0.02 MG/ML Cartridge [Edex]1 ML Alprostadil 0.5 MG/ML Injection [Prostin VR]
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Narrower (17)

15(S)-15-methylprostaglandin E115-keto-prostaglandin E015-ketoprostaglandin EAY 23626
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Broader (3)

Platelet Aggregation InhibitorsProstaglandins EVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Arachidonic acid and other unsaturated fatty acids and some of their metabolites function as endogenous antimicrobial molecules: A review
  • U. Das
  • Journal of advanced research
  • 2018
    • Corpus ID: 49888026
Graphical abstract Scheme showing relationship among M1 and M2 macrophages, cytokines, bioactive lipids, eicosanoids and ROS. 
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Highly Cited
2009
Highly Cited
2009
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal… Expand
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Highly Cited
2007
Highly Cited
2007
Infection with chikungunya virus in Italy: an outbreak in a temperate region
BACKGROUND Chikungunya virus (CHIKV), which is transmitted by Aedes spp mosquitoes, has recently caused several outbreaks on… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.
CONTEXT Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative… Expand
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Highly Cited
2006
Highly Cited
2006
Erectile dysfunction.
From the University of California School of Medicine, San Francisco. Address reprint requests to Dr. Lue at the Department of… Expand
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Highly Cited
2000
Highly Cited
2000
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.
Prostaglandin J(2) (PGJ(2)) and its metabolites Delta(12)-PGJ(2) and 15-deoxy-Delta(12,14)-PGJ(2) (15d-PGJ(2)) are naturally… Expand
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Highly Cited
1999
Highly Cited
1999
Inducible cyclooxygenase may have anti-inflammatory properties
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains… Expand
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Highly Cited
1997
Highly Cited
1997
Treatment of men with erectile dysfunction with transurethral alprostadil. Medicated Urethral System for Erection (MUSE) Study Group.
BACKGROUND Erectile dysfunction in men is common. We evaluated a system by which alprostadil (prostaglandin E1) is delivered… Expand
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Is this relevant?
Highly Cited
1997
Highly Cited
1997
The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene*
PPARγ is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of the human PPARγ cDNA and gene was… Expand
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Highly Cited
1990
Highly Cited
1990
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.
Increasing attention has focused on the role of free radicals derived from oxygen in the pathophysiology of a wide variety of… Expand
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