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Alprostadil

Known as: Alprostadilum, PGE1, Lipo PGE1 
The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Chikungunya virus (CHIKV), which is transmitted by Aedes spp mosquitoes, has recently caused several outbreaks on… Expand
Highly Cited
2006
Highly Cited
2006
CONTEXT Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative… Expand
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Highly Cited
2006
Highly Cited
2006
From the University of California School of Medicine, San Francisco. Address reprint requests to Dr. Lue at the Department of… Expand
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Review
2001
Review
2001
SUMMARY The gram-positive bacterium Listeria monocytogenes is the causative agent of listeriosis, a highly fatal opportunistic… Expand
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Highly Cited
1999
Highly Cited
1999
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Erectile dysfunction in men is common. We evaluated a system by which alprostadil (prostaglandin E1) is delivered… Expand
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Review
1996
Review
1996
Prostaglandin endoperoxide H synthases (PGHSs) catalyze the conversion of arachidonic acid and O2 to PGH2, the committed step in… Expand
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Highly Cited
1990
Highly Cited
1990
Increasing attention has focused on the role of free radicals derived from oxygen in the pathophysiology of a wide variety of… Expand
Highly Cited
1976
Highly Cited
1976
Microsomes prepared from rabbit or pig aortas transformed endoperoxides (PGG2 or PGH2) to an unstable substance (PGX) that… Expand