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Alprostadil

Known as: Alprostadilum, PGE1, Lipo PGE1 
The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that… Expand
National Institutes of Health

Related topics

Related topics

45 relations
0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe [Caverject]1 ML Alprostadil 0.02 MG/ML Cartridge [Edex]1 ML Alprostadil 0.5 MG/ML Injection [Prostin VR]
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Narrower (17)

15(S)-15-methylprostaglandin E115-keto-prostaglandin E015-ketoprostaglandin EAY 23626
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Broader (3)

Platelet Aggregation InhibitorsProstaglandins EVasodilator Agents

Papers overview

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Highly Cited
2009
Highly Cited
2009
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal… Expand
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Highly Cited
2007
Highly Cited
2007
Infection with chikungunya virus in Italy: an outbreak in a temperate region
BACKGROUND Chikungunya virus (CHIKV), which is transmitted by Aedes spp mosquitoes, has recently caused several outbreaks on… Expand
Highly Cited
2006
Highly Cited
2006
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.
CONTEXT Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative… Expand
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Highly Cited
2006
Highly Cited
2006
Erectile dysfunction.
From the University of California School of Medicine, San Francisco. Address reprint requests to Dr. Lue at the Department of… Expand
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Review
2001
Review
2001
Listeria Pathogenesis and Molecular Virulence Determinants
SUMMARY The gram-positive bacterium Listeria monocytogenes is the causative agent of listeriosis, a highly fatal opportunistic… Expand
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Highly Cited
1999
Highly Cited
1999
Inducible cyclooxygenase may have anti-inflammatory properties
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains… Expand
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Highly Cited
1997
Highly Cited
1997
Treatment of men with erectile dysfunction with transurethral alprostadil. Medicated Urethral System for Erection (MUSE) Study Group.
BACKGROUND Erectile dysfunction in men is common. We evaluated a system by which alprostadil (prostaglandin E1) is delivered… Expand
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Review
1996
Review
1996
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2*
Prostaglandin endoperoxide H synthases (PGHSs) catalyze the conversion of arachidonic acid and O2 to PGH2, the committed step in… Expand
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Highly Cited
1990
Highly Cited
1990
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.
Increasing attention has focused on the role of free radicals derived from oxygen in the pathophysiology of a wide variety of… Expand
Highly Cited
1976
Highly Cited
1976
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
Microsomes prepared from rabbit or pig aortas transformed endoperoxides (PGG2 or PGH2) to an unstable substance (PGX) that… Expand
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