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Alprostadil
Known as:
Alprostadilum
, PGE1
, Lipo PGE1
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The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that…
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National Institutes of Health
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Related topics
Related topics
45 relations
0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe
0.5 ML Alprostadil 0.02 MG/ML Prefilled Syringe [Caverject]
1 ML Alprostadil 0.02 MG/ML Cartridge [Edex]
1 ML Alprostadil 0.5 MG/ML Injection [Prostin VR]
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Narrower (17)
15(S)-15-methylprostaglandin E1
15-keto-prostaglandin E0
15-ketoprostaglandin E
AY 23626
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Broader (3)
Platelet Aggregation Inhibitors
Prostaglandins E
Vasodilator Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
K. Nemeth
,
A. Leelahavanichkul
,
+11 authors
É. Mezey
Nature Network Boston
2009
Corpus ID: 1258169
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal…
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Highly Cited
2007
Highly Cited
2007
Infection with chikungunya virus in Italy: an outbreak in a temperate region
G. Rezza
,
L. Nicoletti
,
+13 authors
A. Cassone
The Lancet
2007
Corpus ID: 11571946
Highly Cited
2006
Highly Cited
2006
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.
L. Monnier
,
E. Mas
,
+4 authors
C. Colette
JAMA
2006
Corpus ID: 24233529
CONTEXT Glycemic disorders, one of the main risk factors for cardiovascular disease, are associated with activation of oxidative…
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Highly Cited
2006
Highly Cited
2006
Erectile dysfunction.
A. L. A S T A I
,
R. J. J. W. O O D
,
+4 authors
Penile Flaccidity
Harvard men's health watch
2006
Corpus ID: 19978
From the University of California School of Medicine, San Francisco. Address reprint requests to Dr. Lue at the Department of…
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Review
2001
Review
2001
Listeria Pathogenesis and Molecular Virulence Determinants
J. Vázquez-Boland
,
M. Kuhn
,
+6 authors
J. Kreft
Clinical Microbiology Reviews
2001
Corpus ID: 41234639
SUMMARY The gram-positive bacterium Listeria monocytogenes is the causative agent of listeriosis, a highly fatal opportunistic…
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Highly Cited
1999
Highly Cited
1999
Inducible cyclooxygenase may have anti-inflammatory properties
D. Gilroy
,
P. Colville-Nash
,
D. Willis
,
J. Chivers
,
M. Paul-Clark
,
D. Willoughby
Nature Network Boston
1999
Corpus ID: 20051530
Cyclooxygenase (COX) has two isoforms. Generally, COX 1 is constitutively expressed in most tissues, where it maintains…
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Highly Cited
1997
Highly Cited
1997
Treatment of men with erectile dysfunction with transurethral alprostadil. Medicated Urethral System for Erection (MUSE) Study Group.
H. Padma-nathan
,
W. Hellstrom
,
+9 authors
N. Gesundheit
New England Journal of Medicine
1997
Corpus ID: 205037551
BACKGROUND Erectile dysfunction in men is common. We evaluated a system by which alprostadil (prostaglandin E1) is delivered…
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Review
1996
Review
1996
Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2*
William L. Smith
,
R. Garavito
,
D. Dewitt
Journal of Biological Chemistry
1996
Corpus ID: 28773783
Prostaglandin endoperoxide H synthases (PGHSs) catalyze the conversion of arachidonic acid and O2 to PGH2, the committed step in…
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Highly Cited
1990
Highly Cited
1990
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.
J. Morrow
,
K. Hill
,
R. Burk
,
T. M. Nammour
,
K. Badr
,
L. Roberts
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 25742049
Increasing attention has focused on the role of free radicals derived from oxygen in the pathophysiology of a wide variety of…
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Highly Cited
1976
Highly Cited
1976
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
S. Moncada
,
R. Gryglewski
,
S. Bunting
,
J. Vane
Nature
1976
Corpus ID: 4279030
Microsomes prepared from rabbit or pig aortas transformed endoperoxides (PGG2 or PGH2) to an unstable substance (PGX) that…
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