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AmpliChip

AmpliChip is a family of clinical tests from the Swiss healthcare company Hoffmann-La Roche which aim to find out the patients' genotype using micro… 
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AmpliChip CYP450 Test

Papers overview

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2016
2016
CYP2D6 Metabolizer Phenotypes in Patients Undergoing ECT After Antidepressant Therapy
Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are common mental disorders. According to present… 
2013
2013
Tamoxifen Pharmacogenetics: CYP2D6 and Other Variables Influencing Tamoxifen and Tamoxifen Metabolite Exposure
Author(s): Tchu, Simone Ming | Advisor(s): Wu, Alan HB | Abstract: Tamoxifen is a selective estrogen receptor modulator (SERM… 
2012
2012
CYP450 2D6 Genotype and Flecainide Efficacy in the Treatment of Patients with Lone Atrial Fibrillation
Background : CYP2D6 has been linked to one of four phenotypes: a) ultra-rapid metabolizers (UM), with multiple gene copies; b… 
2010
2010
EVALUATION OF TP53 MUTATIONS WITH THE AMPLICHIP P53 ARRAY IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): HIGHER SENSITIVITY AND CORRELATION WITH CLINICAL OUTCOME
2008
2008
Standardizing the Decision Process to Personalize a Therapy with a Theranostic : The Options for Test Index ( OFT i )
While the top pharmaceutical companies have all made investments at an R&D stage in biomarkers and genetics to aid drug selection… 
2008
2008
P53 EVALUATION IN 98 CLL PATIENTS BY AMPLICHIP P53 ARRAY REVEALS A HIGH PERCENTAGE OF MUTATIONS AND POLYMORPHISMS
2006
2006
Making the most of microarrays
A major, multicenter study of microarray performance is a first step in translating the technology from bench to bedside. 
2006
2006
High Frequency of P53 Mutations Detected by a Microarray Resequencing Assay, the AmpliChip P53 Test, in AML with a Complex Aberrant Karyotype.
Acute myeloid leukemia (AML) is heterogeneous in morphology, cytogenetics, and prognosis. On the basis of cytogenetics it can be… 
2005
2005
Molecular diagnostics: challenges and possibilities
Modern laboratory diagnostics is characterized by a number of processes, like computerization and robotization, significant… 
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