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AmpliChip CYP450 Test

AmpliChip CYP450 Test is a clinical test from Roche. The test aims to find the specific gene types (a genotype) of the patient that will determine… 
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AmpliChip

Papers overview

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Review
2018
Review
2018
2-1-2016 Role of Pharmacogenetics in Improving the Safety of Psychiatric Care by Predicting the Potential Risks of Mania in CYP 2 D 6 Poor Metabolizers Diagnosed With Bipolar Disorder
One of the main concerns in psychiatric care is safety related to drug management. Pharmacogenetics provides an important tool to… 
2015
2015
The Role of CYP2D6 polymorphisms in breast cancer patients
• The Roche DNA microarray-based pharmacogenetics test for CYP2D6 and CYP2C19 variants (approved by FDA), called AmplyChip CYP450… 
2014
2014
PHARMACOGENETIC ASPECTS WHICH INFLUENCE THE PHARMACOKINETIC PROPERTIES OF ATYPICAL ANTIPSYCHOTICS – PRELIMINARY STUDY
Patients under medical treatment show significant differences in treatment response. Among the reasons of this variability, the… 
Review
2014
Review
2014
Genetics of antipsychotic drug outcome and implications for the clinician: into the limelight
Background and purpose Antipsychotics (APs) are the primary method of treatment for schizophrenia and other psychotic disorders… 
2014
2014
Characterization of AmpliChip CYP450 test no-calls in the clinical setting: identification of novel CYP2D6 variants
2011
2011
Early immunocastration of male pigs
The aim of this study was to investigate the effects of prepubertal or early pubertal vaccination against GnRH using Improvac… 
2009
2009
The influence of methanandamide on the activity of hepatic CYP1A2 and 2C6 isoenzymes in preclinical experiment
Study aimed on the influence of methanadamide intraperitoneal pretreatment on rat CYP 1A2 and 2C6 activity in liver. 
2007
2007
Effect of O-desmethylvenlafaxine on the content of cytomicrosome cytochrome P450 (CYP450) enzyme and activity of CYP2D6 and CYP3A4 in rat liver
Objective To study the effect of O-desmethylvenlafaxine(ODV)on the content of cytochrome P450(CYP450)and activity of CYP2D6 and… 
2005
2005
DNA microarrays: Microarrays move downstream
Array-based methods are now being applied in a diagnostic setting and offer the possibility of analysing multiple analytes (and… 
2004
2004
CYP450 Polymorphisms and Antidepressants: An Introduction to Pharmacogenomics
The effect of cytochrome P450 (CYP) enzymes on psychotropic medication metabolism and interactions is well known (see, e.g… 
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