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Amobarbital
Known as:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
, 5-Ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
, Amobarbital [Chemical/Ingredient]
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A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression…
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National Institutes of Health
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Related topics
Related topics
43 relations
Narrower (18)
3'-hydroxyamobarbital
Amesec
Amobarbital Sodium
Amsal
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Airway Obstruction
Amobarbital Sodium 500 MG Injection [Amytal]
Amobarbital:PrThr:Pt:Gast fld:Ord
Amobarbital:PrThr:Pt:Urine:Ord
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Broader (5)
Barbiturates
GABA Modulators
Hypnotics
Hypnotics and Sedatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Functional MRI and Wada studies in patients with interhemispheric dissociation of language functions
Dongwook Lee
,
S. Swanson
,
+4 authors
J. Binder
Epilepsy & Behavior
2008
Corpus ID: 23436648
Highly Cited
2000
Highly Cited
2000
Anosognosia and asomatognosia during intracarotid amobarbital inactivation
K. Meador
,
David W Loring
,
Todd E. Feinberg
,
Gregory P. Lee
,
M. Nichols
Neurology
2000
Corpus ID: 12025256
Background: Anosognosia (i.e., denial of hemiparesis) and asomatognosia (i.e., inability to recognize the affected limb as one’s…
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Highly Cited
1991
Highly Cited
1991
Dominant-side intracarotid amobarbital spares comprehension of word meaning.
J. Hart
,
R. Lesser
,
R. Fisher
,
P. Schwerdt
,
R. Bryan
,
B. Gordon
Archives of Neurology
1991
Corpus ID: 23101242
Abolition of speech production after intracarotid amobarbital injection is generally considered evidence for language laterality…
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Highly Cited
1981
Highly Cited
1981
Observations on spontaneous facial expression after focal cerebral excisions and after intracarotid injection of sodium amytal
B. Kolb
,
B. Milner
Neuropsychologia
1981
Corpus ID: 28905533
Highly Cited
1979
Highly Cited
1979
Sodium Amylobarbitone and Responses to Nonreward*
J. Feldon,
,
A. Guillamón
,
J. Gray
,
H. de Wit
,
N. McNaughton
Quarterly Journal of Experimental Psychology
1979
Corpus ID: 9696887
Three experiments are reported testing two alternative hypotheses concerning the behavioural effects of sodium amylobarbitone (SA…
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Highly Cited
1977
Highly Cited
1977
Plasma concentrations of benzodiazepines.
A. Bond
,
D. M. Hailey
,
M. Lader
British Journal of Clinical Pharmacology
1977
Corpus ID: 33608358
1. Twenty anxious patients were treated with medazepam, diazepam, chlordiazepoxide, amylobarbitone and placebo, each given in…
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Highly Cited
1976
Highly Cited
1976
The effects of low doses of amylobarbitone sodium and diazepam on human performance.
J. Hart
,
H. Hill
,
C. Bye
,
R. Wilkinson
,
A. W. Peck
British Journal of Clinical Pharmacology
1976
Corpus ID: 30871627
The effects of diazepam (2.5 and 5 mg) and amylobarbitone sodium (50 and 100 mg) on performance and subjective effects were…
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Highly Cited
1974
Highly Cited
1974
The effect of age on the hydroxylation of amylobarbitone sodium in man.
R. Irvine
,
J. Grove
,
P. Toseland
,
J. Trounce
British Journal of Clinical Pharmacology
1974
Corpus ID: 13448479
1 Following a single oral dose of amylobarbitone sodium it has been shown that a group of young subjects convert a higher…
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Highly Cited
1972
Highly Cited
1972
Metabolism of amylobarbitone in patients with chronic liver disease
G. Mawer
,
N. Miller
,
L. A. Turnberg
British Journal of Pharmacology
1972
Corpus ID: 32548251
1 A single dose of amylobarbitone (3·23 mg/kg) was given by intravenous injection to each of ten healthy controls and two groups…
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Highly Cited
1966
Highly Cited
1966
Combined Effects of Chlordiazepoxide and Dexamphetamine on Activity of Rats in an Unfamiliar Environment
R. Rushton
,
H. Steinberg
Nature
1966
Corpus ID: 4161999
IN previous experiments we found that, over a wide range of doses, amphetamine and amylobarbitone affected relatively little the…
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