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Aminopterin

Known as: Aminopteroylglutamic Acid, N-(4-{[(2,4-Diamino-6-pteridinyl)methyl]amino}benzoyl)glutamic acid, 4-Amino-PGA 
A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (23)

10-deazaaminopterin10-propargyl-10-deazaaminopterin10-propargylaminopterin11-oxahomoaminopterin
Aminopterin SodiumIn BloodNCIt Antineoplastic Agent Terminologyagonists

Broader (4)

Antineoplastic AgentsFolic Acid AntagonistsPesticidesPteridines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Layer-by-layer self-assembled polyelectrolyte multilayers with embedded liposomes: immobilized submicronic reactors for mineralization.
The development of chemical reactions in nanospaces is of paramount importance for the development of active nanodevices… 
Highly Cited
1988
Highly Cited
1988
Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W.
We have assigned several mouse cDNA and genomic clones to the W region of mouse chromosome 5, established their position with… 
Highly Cited
1986
Highly Cited
1986
Functional expression of a human Na+/H+ antiporter gene transfected into antiporter-deficient mouse L cells.
To clone the gene for the human Na+/H+ antiporter, we first constructed a stable mouse LTK- cell line (LAP1) lacking Na+/H… 
Highly Cited
1983
Highly Cited
1983
Monoclonal antibodies to carcinoembryonic antigen: ionic strength as a factor in the selection of antibodies for immunoscintigraphy.
As part of an ongoing effort to improve the technique of immunoscintigraphy for the detection of human carcinomas with… 
Highly Cited
1978
Highly Cited
1978
Human α-globin gene expression following chromosomal dependent gene transfer into mouse erythroleukemia cells
Highly Cited
1970
Highly Cited
1970
Congenital defects in folate utilization.
Highly Cited
1970
Highly Cited
1970
Evidence against the folate-mediated formylation of formyl-accepting methionyl transfer ribonucleic acid in Streptococcus faecalis R.
Highly Cited
1969
Highly Cited
1969
The effects of 5-Bromodeoxyuridine on the differentiation of chondrocytes in vitro.
Highly Cited
1957
Highly Cited
1957
The inactivation of folic acid by liver.
Highly Cited
1950
Highly Cited
1950
On the Mechanism of Action of Aminopterin.∗
Summary Rat liver slices form from synthetic folic acid (PGA) a factor (CF) utilized for growth by Leuconostoc citrovorum; this… 
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