Aminopterin

Known as: Aminopteroylglutamic Acid, N-(4-{[(2,4-Diamino-6-pteridinyl)methyl]amino}benzoyl)glutamic acid, 4-Amino-PGA 
A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
  • 2014
SUMMARY A novel polymer-based multi-drug nanosized conjugate was developed. We demonstrate here the advantage of a combined… (More)
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2011
2011
OBJECTIVE We developed a predictive model for significant fibrosis in chronic hepatitis B (CHB) based on routinely available… (More)
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Review
1999
Review
1999
Maternal exposures to aminopterin and methotrexate have been associated with a pattern of malformation which includes prenatal… (More)
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Highly Cited
1997
Highly Cited
1997
Editing of the non-protein amino acid homocysteine, a frequent type of error-correcting process in amino acid selection for… (More)
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1995
1995
Affinity-purified gametocyte antigens (APGA) from Eimeria maxima, emulsified in Freund's adjuvant, were injected intramuscularly… (More)
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Highly Cited
1989
Highly Cited
1989
We have selected mutations in genes encoding components of the signaling pathway for alpha interferon (IFN-alpha) by using a… (More)
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1984
1984
A group of folate analogs of the 10-deaza-aminopterin series, which were designed on the basis of the results of an intensive… (More)
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1984
1984
Structural modification of the N10 position of 4-amino folates affects mediated membrane transport in mammalian cells but has… (More)
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1981
1981
The monoclonal antibody, RA3-2C2, appears to be specific for cells within the B cell lineage. This antibody does not recognize… (More)
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1979
1979
The polar lipids of Streptococcus pneumoniae wild type and aminopterin-resistant strains were analysed. The membrane contained… (More)
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