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10-propargyl-10-deazaaminopterin

Known as: (2S)-2-[[4-[(1RS)-1-[(2, 4-Diaminopteridin-6-yl)methyl]but-3-ynyl]benzoyl]amino]pentanedioic Acid, N-(4-{1-[(2,4-Diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic Acid, PDX 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Aminopterin

Narrower (1)

Pralatrexate
analogs & derivativesprobenecid/10-propargyl-10-deaxaaminopterin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Correction: Inhibition of Furin-mediated Processing Results in Suppression of Astrocytoma Cell Growth and Invasiveness
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential… 
2018
2018
A New Types of Polymorphic Form of 10-Propargyl-10-Deazaaminopterin, from SL: As a Refractory Peripheral T-cell Lymphoma Drug
A new crystal form of 10-Propargyl-10-Deazaaminopterin, form SL, was discovered which is thermodynamically stable, shows long… 
2015
2015
Inside an Open Educational Resource Initiative: PDX Open at
2012
2012
Abstract 1725: Molecular determinants of Sorafenib sensitivity in renal and non small cell lung - Patient derived tumors engrafted in nude mice
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Introduction: Sorafenib (Nexavar(®)) is a potent… 
2011
2011
Methods for extending progression-free survival using 10-propargyl-10-deazaaminopterin
The present invention includes a method of reversing the tendency to gradual resistance to continuous treatment for T-cell… 
2007
2007
Using Zena™ Prototypes as Perching Deterrents on Airfield Signage
Airfields often provide very attractive habitat for many avian species, including a variety of raptor species. Avian wildlife at… 
2005
2005
Treatment of T-cell lymphoma using 10-propargyl-10-deazaaminopterin
T cell lymphoma is treated by administering a T cell-aza aminopterin having to suffer from lymphoma a therapeutically effective… 
2004
2004
PDX-WAP content converting method and system
The method includes following steps: the WAP terminal transmits request message to PDX gateway through WAP gateway; the PDX… 
2000
2000
Phase I and Pharmacokinetic Study of 10-Propargyl-10-deazaaminopterin , a New Antifolate 1
The 10-deazaaminopterins are a new class of rationally designed antifolates demonstrating greater antitumor effects than… 
1997
1997
Compositions purified 10-propargyl-10-deazaaminopterin and methods of use in treating tumors.
It HAS SHOWN THAT compositions highly purified 10 - propargyl - 10 - deazaaminopterin (10 - propargyl 10dAM), tested in xenograft… 
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