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Aminolevulinic Acid

Known as: Delta Aminolevulinic Acid, delta-ALA, 5-Amino-4-oxopentanoic Acid 
The active ingredient in a drug used to treat actinic keratosis (a skin condition that may become cancer). The drug is also being studied in the… Expand
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (13)

2-amino-5-hydroxy-4-oxopentanoic acid5-aminolaevulinic acid-n-pentylester5-chloro-4-oxo-L-norvaline5-diazo-4-oxonorvaline
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AlanineAminolevulinate 200 MG/ML Topical Solution [Levulan]Delta aminolevulinate:MCnc:Pt:Plas:QnDelta aminolevulinate:MRat:24H:Urine:Qn
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Broader (2)

Photosensitizing Agentslevulinic acid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.
BACKGROUND 5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins… Expand
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Highly Cited
2000
Highly Cited
2000
Fluorescence-guided resection of glioblastoma multiforme by using 5-aminolevulinic acid-induced porphyrins: a prospective study in 52 consecutive patients.
OBJECT It has been established that 5-aminolevulinic acid (5-ALA) induces the accumulation of fluorescent porphyrins in… Expand
Highly Cited
1998
Highly Cited
1998
Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence.
OBJECTIVE Survival after surgery and radiotherapy for the treatment of malignant gliomas is linked to the completeness of tumor… Expand
Review
1997
Review
1997
5‐Aminolevulinic acid‐based photodynamic therapy
Photodynamic therapy (PDT) for cancer patients has developed into an important new clinical treatment modality in the past 25… Expand
Review
1997
Review
1997
5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research
The iron(I1) complex of protoporphyrin IX (PpIX)? (heme) is bound to different proteins to form key biomolecules (hemoproteins… Expand
Highly Cited
1996
Highly Cited
1996
Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence.
PURPOSE We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic… Expand
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Highly Cited
1993
Highly Cited
1993
cPLA2 is phosphorylated and activated by MAP kinase
Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… Expand
Highly Cited
1990
Highly Cited
1990
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
5-Aminolaevulinic acid (ALA) is a precursor of protoporphyrin IX (Pp IX) in the biosynthetic pathway for haem. Certain types of… Expand
Highly Cited
1982
Highly Cited
1982
Delta-aminolevulinic acid dehydratase assay.
gamma-Aminolevulinic acid (ALA) dehydratase catalyzes the synthesis of porphobilinogen (PBG) from two molecules of ALA. A… Expand
Highly Cited
1956
Highly Cited
1956
THE OCCURRENCE AND DETERMINATION OF δ-AMINOLEVULINIC ACID AND PORPHOBILINOGEN IN URINE
A number of recent studies have shown that &aminolevulinic acid (SAL) and porphobilinogen (PBG) are early intermediates in the… Expand
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