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Amidophosphoribosyltransferase

Known as: ATase, Phosphoribosyl Pyrophosphate Amidotransferase, Amidophosphoribosyltransferase [Chemical/Ingredient] 
An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and… 
National Institutes of Health

Related topics

Related topics

19 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GeneGout

Narrower (1)

Prat2 protein, Drosophila

Broader (1)

pentosyltransferase

Papers overview

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Highly Cited
2004
Highly Cited
2004
Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle.
Intramuscular triacylglycerols (IMTG) are proposed to be an important metabolic substrate for contracting muscle, although this… 
Highly Cited
1999
Highly Cited
1999
Characterization of the GlnK protein of Escherichia coli
The GlnK and PII signal transduction proteins are paralogues that play distinct roles in nitrogen regulation. Although cells… 
Highly Cited
1999
Highly Cited
1999
Relationship between DNA adduct levels, repair enzyme, and apoptosis as a function of DNA methylation by azoxymethane.
DNA alkylating agent exposure results in the formation of a number of DNA adducts, with O6-methyl-deoxyguanosine (O6-medG) being… 
Highly Cited
1996
Highly Cited
1996
Induction of murine O6-alkylguanine-DNA-alkyltransferase in response to ionising radiation is p53 gene dose dependent.
Expression of both the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase) and the p53 tumour suppressor protein are… 
Highly Cited
1988
Highly Cited
1988
Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.
O6-alkylguanine-DNA-alkyltransferase (ATase)-deficient murine haemopoietic stem cells were transfected, following electroporation… 
Highly Cited
1981
Highly Cited
1981
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells.
Highly Cited
1979
Highly Cited
1979
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal…
1. GPAT (glycerol phosphate acyltransferase) and DHAPAT (dihydroxyacetone phosphate acyltransferase) activities were measured… 
Highly Cited
1976
Highly Cited
1976
Key enzymes of IMP metabolism: transformation and proliferation-linked alterations in gene expression.
Highly Cited
1969
Highly Cited
1969
Inhibition of phosphoribosyl pyrophosphate amidotransferase from Ehrlich ascites-tumour cells by thiopurine nucleotides.
Highly Cited
1959
Highly Cited
1959
The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis.
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