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Amidophosphoribosyltransferase
Known as:
ATase
, Phosphoribosyl Pyrophosphate Amidotransferase
, Amidophosphoribosyltransferase [Chemical/Ingredient]
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An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and…
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National Institutes of Health
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Related topics
Related topics
19 relations
Carbohydrate Metabolism
Enzyme Gene
Glycosyltransferase Gene
Gout
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Narrower (1)
Prat2 protein, Drosophila
Broader (1)
pentosyltransferase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Escherichia coli glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49): kinetic characterization of regulation by PII, PII-UMP, glutamine, and alpha-ketoglutarate.
P. Jiang
,
A. Mayo
,
A. Ninfa
Biochemistry
2007
Corpus ID: 30373893
Glutamine synthetase adenylyltranferase (ATase, EC 2.7.7.49) catalyzes the adenylylation and deadenylylation of glutamine…
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Highly Cited
2004
Highly Cited
2004
Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle.
M. Watt
,
A. Holmes
,
G. Steinberg
,
J. Mesa
,
B. Kemp
,
M. Febbraio
American Journal of Physiology. Endocrinology and…
2004
Corpus ID: 27895850
Intramuscular triacylglycerols (IMTG) are proposed to be an important metabolic substrate for contracting muscle, although this…
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1994
1994
Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine.
R. Elder
,
G. Margison
,
J. Rafferty
Biochemical Journal
1994
Corpus ID: 38148630
The action of O6-benzylguanine (O6-BzlG) on recombinant mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases…
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Highly Cited
1988
Highly Cited
1988
Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.
J. Jelinek
,
K. Kleibl
,
T. Dexter
,
Geoffrey P. Margison
Carcinogenesis
1988
Corpus ID: 46406596
O6-alkylguanine-DNA-alkyltransferase (ATase)-deficient murine haemopoietic stem cells were transfected, following electroporation…
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Highly Cited
1984
Highly Cited
1984
Glutamine nucleotide sequence of Saccharomyces cerevisiae ADE4 encoding phosphoribosylpyrophosphate amidotransferase.
P. Mäntsälä
,
H. Zalkin
Journal of Biological Chemistry
1984
Corpus ID: 35117868
Highly Cited
1982
Highly Cited
1982
Nucleotide sequence of Escherichia coli purF and deduced amino acid sequence of glutamine phosphoribosylpyrophosphate amidotransferase.
J. Y. TsoS
,
Howard
,
Magda van Cleemputl
,
Charles Yanofskyl
,
John M. Smith
Journal of Biological Chemistry
1982
Corpus ID: 13376489
1981
1981
Reaction of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase with oxygen: chemistry and regulation by ligands.
D. Bernlohr
,
R. Switzer
Biochemistry
1981
Corpus ID: 10389737
The inactivation of glutamine phosphoribosylpyrophosphate amidotransferase by reaction of its iron-sulfur center with O2 is…
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Highly Cited
1979
Highly Cited
1979
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal…
E. J. Bates
,
E. Saggerson
Biochemical Journal
1979
Corpus ID: 32947987
1. GPAT (glycerol phosphate acyltransferase) and DHAPAT (dihydroxyacetone phosphate acyltransferase) activities were measured…
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Highly Cited
1974
Highly Cited
1974
Multiple mechanisms of regulation of purine biosynthesis de novo in intact tumor cells.
A. S. Bagnara
,
A. Letter
,
J. Henderson
Biochimica et Biophysica Acta
1974
Corpus ID: 1267580
Highly Cited
1959
Highly Cited
1959
The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis.
J. Wyngaarden
,
D. M. Ashton
Journal of Biological Chemistry
1959
Corpus ID: 40311098
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