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Amidophosphoribosyltransferase
Known as:
ATase
, Phosphoribosyl Pyrophosphate Amidotransferase
, Amidophosphoribosyltransferase [Chemical/Ingredient]
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An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and…
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National Institutes of Health
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Related topics
Related topics
19 relations
Carbohydrate Metabolism
Enzyme Gene
Glycosyltransferase Gene
Gout
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Narrower (1)
Prat2 protein, Drosophila
Broader (1)
pentosyltransferase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Reduced plasma FFA availability increases net triacylglycerol degradation, but not GPAT or HSL activity, in human skeletal muscle.
M. Watt
,
A. Holmes
,
G. Steinberg
,
J. Mesa
,
B. Kemp
,
M. Febbraio
American Journal of Physiology. Endocrinology and…
2004
Corpus ID: 27895850
Intramuscular triacylglycerols (IMTG) are proposed to be an important metabolic substrate for contracting muscle, although this…
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Highly Cited
1999
Highly Cited
1999
Characterization of the GlnK protein of Escherichia coli
M. R. Atkinson
,
A. Ninfa
Molecular Microbiology
1999
Corpus ID: 6747306
The GlnK and PII signal transduction proteins are paralogues that play distinct roles in nitrogen regulation. Although cells…
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Highly Cited
1999
Highly Cited
1999
Relationship between DNA adduct levels, repair enzyme, and apoptosis as a function of DNA methylation by azoxymethane.
Mee Young Hong
,
R. Chapkin
,
+5 authors
J. Lupton
Cell growth & differentiation : the molecular…
1999
Corpus ID: 19637215
DNA alkylating agent exposure results in the formation of a number of DNA adducts, with O6-methyl-deoxyguanosine (O6-medG) being…
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Highly Cited
1996
Highly Cited
1996
Induction of murine O6-alkylguanine-DNA-alkyltransferase in response to ionising radiation is p53 gene dose dependent.
J. Rafferty
,
A. Clarke
,
D. Sellappan
,
M. S. Koref
,
I. Frayling
,
G. Margison
Oncogene
1996
Corpus ID: 30545550
Expression of both the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (ATase) and the p53 tumour suppressor protein are…
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Highly Cited
1988
Highly Cited
1988
Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.
J. Jelinek
,
K. Kleibl
,
T. Dexter
,
Geoffrey P. Margison
Carcinogenesis
1988
Corpus ID: 46406596
O6-alkylguanine-DNA-alkyltransferase (ATase)-deficient murine haemopoietic stem cells were transfected, following electroporation…
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Highly Cited
1981
Highly Cited
1981
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells.
E. Cadman
,
R. Heimer
,
C. Benz
Journal of Biological Chemistry
1981
Corpus ID: 19198741
Highly Cited
1979
Highly Cited
1979
A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal…
E. J. Bates
,
E. Saggerson
Biochemical Journal
1979
Corpus ID: 32947987
1. GPAT (glycerol phosphate acyltransferase) and DHAPAT (dihydroxyacetone phosphate acyltransferase) activities were measured…
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Highly Cited
1976
Highly Cited
1976
Key enzymes of IMP metabolism: transformation and proliferation-linked alterations in gene expression.
G. Weber
,
N. Prajda
,
R. Jackson
Advances in Enzyme Regulation
1976
Corpus ID: 38071323
Highly Cited
1969
Highly Cited
1969
Inhibition of phosphoribosyl pyrophosphate amidotransferase from Ehrlich ascites-tumour cells by thiopurine nucleotides.
B. S. Tay
,
R. Lilley
,
A. W. Murray
,
M. R. Atkinson
Biochemical Pharmacology
1969
Corpus ID: 46437652
Highly Cited
1959
Highly Cited
1959
The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis.
J. Wyngaarden
,
D. M. Ashton
Journal of Biological Chemistry
1959
Corpus ID: 40311098
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