Amidophosphoribosyltransferase

Known as: ATase, Phosphoribosyl Pyrophosphate Amidotransferase, Amidophosphoribosyltransferase [Chemical/Ingredient] 
An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and… (More)
National Institutes of Health

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18 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GeneGout
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Broader (1)

pentosyltransferase

Papers overview

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Highly Cited
2006
Highly Cited
2006
Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.
Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first step during de novo synthesis of triacylglycerol. It has… (More)
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Review
2003
Review
2003
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
O(6)-Alkylguanine-DNA alkyltransferase (ATase) confers resistance to many of the biological effects of certain classes of… (More)
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Highly Cited
2002
Highly Cited
2002
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition.
Microsomal and mitochondrial isoforms of glycerol-3-phosphate acyltransferase (GPAT; E.C. 2.3.1.15) catalyze the committed step… (More)
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Review
2002
Review
2002
O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy.
The DNA in human cells is continuously undergoing damage as consequences of both endogenous processes and exposure to exogenous… (More)
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Review
2001
Review
2001
Channeling of substrates and intermediates in enzyme-catalyzed reactions.
The three-dimensional structures of tryptophan synthase, carbamoyl phosphate synthetase, glutamine phosphoribosylpyrophosphate… (More)
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Highly Cited
1998
Highly Cited
1998
Meiotic induction in cumulus cell-enclosed mouse oocytes: involvement of the pentose phosphate pathway.
In this study we tested the hypothesis that the pentose phosphate pathway (PPP) participates in the meiotic induction of mouse… (More)
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Highly Cited
1998
Highly Cited
1998
Role of the GlnK signal transduction protein in the regulation of nitrogen assimilation in Escherichia coli.
Two structurally similar but functionally distinct PII-like proteins, PII and GlnK, regulate nitrogen assimilation in Escherichia… (More)
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Highly Cited
1997
Highly Cited
1997
hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
Loss of expression of the hMLH1 and hPMS2 subunits of the MutLα-mismatch repair complex is a frequent event (9/10) in independent… (More)
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Highly Cited
1995
Highly Cited
1995
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation
THE crystal structures of three amidohydrolases have been determined recently1–3: glutamine PRPP amidotransferase (GAT… (More)
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Highly Cited
1975
Highly Cited
1975
Malignant transformation-linked imbalance: decreased xanthine oxidase activity in hepatomas.
Xanthine oxidase was decreased 2- to 10-fold in all examined rat hepatomas irrespective of the malignancy; growth rate and… (More)
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