FAQ

Amantadine

Known as: 1-aminoadamantane, 1-adamantylamine, Tricyclo[3.3.1.1(3,7)]decan-1-amine 
A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect… (More)

Topic mentions per year

Topic mentions per year

1964-2018
05010019642018

Related topics

Related topics

34 relations

Narrower (14)

2-aminoadamantane4-bromobenzoyl-methyladamantylamineAmanAmantadine Sulfate
(More)

Broader (8)

AdamantaneAnalgesics, Non-NarcoticAntibioticsAntiparkinson Agents
(More)
Amantadine HydrochlorideDrug AllergyDyskinesia, Drug-InducedIn Blood
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Amantadine
Drug Allergy
Parkinson Disease
agonists
Antiviral Agents
Antibiotics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Avian influenza A (H7N9) virus infection in humans: epidemiology, evolution, and pathogenesis.
  • Matloob Husain
  • Infection, genetics and evolution : journal of…
  • 2014
New human influenza A virus strains regularly emerge causing seasonal epidemics and occasional pandemics. Lately, several… (More)
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Highly Cited
2006
Highly Cited
2006
Distribution of amantadine-resistant H5N1 avian influenza variants in Asia.
We examined the distribution of genetic mutations associated with resistance to the M2 ion channel-blocking adamantane… (More)
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Highly Cited
2004
Highly Cited
2004
Guidelines for preventing health-care--associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee.
This report updates, expands, and replaces the previously published CDC "Guideline for Prevention of Nosocomial Pneumonia". The… (More)
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Highly Cited
2004
Highly Cited
2004
Resistant influenza A viruses in children treated with oseltamivir: descriptive study.
BACKGROUND Oseltamivir is an effective inhibitor of influenza virus neuraminidase. Although viruses resistant to oseltamivir… (More)
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Highly Cited
2003
Highly Cited
2003
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine.
Hepatitis C virus (HCV) cannot be grown in vitro, making biochemical identification of new drug targets especially important. HCV… (More)
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Highly Cited
1998
Highly Cited
1998
Amantadine as treatment for dyskinesias and motor fluctuations in Parkinson's disease.
OBJECTIVE To determine the effects of the N-methyl-D-aspartate (NMDA) antagonist amantadine on levodopa-associated dyskinesias… (More)
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Highly Cited
1993
Highly Cited
1993
Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block.
The influenza A virus M2 integral membrane protein has ion channel activity which can be blocked by the antiviral drug amantadine… (More)
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Highly Cited
1992
Highly Cited
1992
Influenza virus M2 protein has ion channel activity.
The influenza virus M2 protein was expressed in Xenopus laevis oocytes and shown to have an associated ion channel activity… (More)
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Highly Cited
1985
Highly Cited
1985
The molecular basis of the specific anti-influenza action of amantadine.
Amantadine (1-aminoadamantane hydrochloride) is effective in the prophylaxis and treatment of influenza A infections. In tissue… (More)
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Highly Cited
1964
Highly Cited
1964
Antiviral Activity of 1-adamantanamine (amantadine).
I-Adamantanamine (amantadine) causes a selective, reproducible, dose-related inhibition of influenza infections in tissue culture… (More)
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