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The M2 protein of influenza A virus is a membrane-spanning tetrameric proton channel targeted by the antiviral drugs amantadine… Expand This report updates the 2005 recommendations by the Advisory Committee on Immunization Practices (ACIP) regarding the use of… Expand Hepatitis C virus (HCV) cannot be grown in vitro, making biochemical identification of new drug targets especially important. HCV… Expand ContextPrevious studies have shown oseltamivir, a neuraminidase inhibitor,
to be effective in preventing influenza and treating… Expand Objective: To determine the effects of the N-methyl-D-aspartate (NMDA) antagonist amantadine on levodopa-associated dyskinesias… Expand Recently, we cloned the human cation transporter hOCT2, a member of a new family of polyspecific transporters from kidney, and… Expand The pharmacological inhibition of excitatory amino acid neurotransmission has evolved to be a major topic in neuropharmacology… Expand The influenza A virus M2 integral membrane protein has ion channel activity which can be blocked by the antiviral drug amantadine… Expand Amantadine (1‐aminoadamantane hydrochloride) is effective in the prophylaxis and treatment of influenza A infections. In tissue… Expand I-Adamantanamine (amantadine) causes a selective, reproducible, dose-related inhibition of influenza infections in tissue culture… Expand