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Amantadine

Known as: 1-aminoadamantane, 1-adamantylamine, Tricyclo[3.3.1.1(3,7)]decan-1-amine 
A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (24)

2-aminoadamantane4-bromobenzoyl-methyladamantylamineAmanAmanta

Broader (6)

AdamantaneAnalgesics, Non-NarcoticAntibioticsAntiparkinson Agents
Amantadine HydrochlorideAmantadine SulfateAmantadine:Susc:Pt:Isolate:OrdQnDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
New platinum(IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistant cell line within homologous…
The aim of this study was to compare anti-tumor potency of platinum(IV) complexes with increasing hydrophobicity of their ligands… 
Highly Cited
1999
Highly Cited
1999
Modified M2 proteins produce heterotypic immunity against influenza A virus.
Highly Cited
1999
Highly Cited
1999
Dual effects of l-3,4-dihydroxyphenylalanine on aromatic l-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine…
1997
1997
In vitro antitumor and antimicrobial activities of N-substituents of maleimide by adamantane and diamantane.
New N-1-adamantylcitraconimide (compound 1) and N-1-diamantylcitraconimide (compound 2) were synthesized by reaction of… 
1996
1996
Combination antiviral therapy for respiratory virus infections.
1995
1995
Microdialysis studies with amantadine and memantine on pharmacokinetics and effects on dopamine turnover.
Amantadine and memantine are in clinical use for the treatment of neurodegenerative diseases such as M. Parkinson and dementia… 
Review
1994
Review
1994
Glutamatergic drugs in Parkinson's disease.
1987
1987
Effects of inhibitors of the cytoplasmic structures and functions on the early phase of infection of cultured cells with simian virus 40.
Highly Cited
1970
Highly Cited
1970
The effect of amantadine on the uptake of dopamine and noradrenaline by rat brain homogenates
Amantadine hydrochloride (1-adamantanamine hydrochloride), an antiviral agent (Davies, Grunert & others, 1964) has been shown to… 
Highly Cited
1970
Highly Cited
1970
The inhibition of lymphocyte blastogenesis by L-asparaginase.
The effect of the enzyme L-asparaginase on in vitro lymphocyte blastogenesis was studied. E.coli L-asparaginase has a reversible… 
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