Skip to search formSkip to main contentSkip to account menu

Amantadine

Known as: 1-aminoadamantane, 1-adamantylamine, Tricyclo[3.3.1.1(3,7)]decan-1-amine 
A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (24)

2-aminoadamantane4-bromobenzoyl-methyladamantylamineAmanAmanta

Broader (6)

AdamantaneAnalgesics, Non-NarcoticAntibioticsAntiparkinson Agents
Amantadine HydrochlorideAmantadine SulfateAmantadine:Susc:Pt:Isolate:OrdQnDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries.
Highly Cited
2007
Highly Cited
2007
Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.
Highly Cited
2004
Highly Cited
2004
Platinum(IV) complex with adamantylamine as nonleaving amine group: synthesis, characterization, and in vitro antitumor activity against a panel of cisplatin-resistant cancer cell lines.
Procedure of the synthesis is described for new platinum(IV) drug LA-12 [(OC-6-43)-bis(acetato)(1-adamantylamine… 
Highly Cited
1999
Highly Cited
1999
Modified M2 proteins produce heterotypic immunity against influenza A virus.
Highly Cited
1999
Highly Cited
1999
Dual effects of l-3,4-dihydroxyphenylalanine on aromatic l-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine…
Highly Cited
1978
Highly Cited
1978
Susceptibility of influenza A viruses to amantadine is influenced by the gene coding for M protein
Influenza A virus recombinants derived from "resistant" and "sensitive" parental viruses were examined for susceptibility to… 
Highly Cited
1970
Highly Cited
1970
The inhibition of lymphocyte blastogenesis by L-asparaginase.
The effect of the enzyme L-asparaginase on in vitro lymphocyte blastogenesis was studied. E.coli L-asparaginase has a reversible… 
Highly Cited
1970
Highly Cited
1970
The effect of amantadine on the uptake of dopamine and noradrenaline by rat brain homogenates
Amantadine hydrochloride (1-adamantanamine hydrochloride), an antiviral agent (Davies, Grunert & others, 1964) has been shown to… 
Highly Cited
1970
Highly Cited
1970
In vivo Selection of an Influenza A2 Strain resistant to Amantadine
ACQUIRED resistance to chemotherapeutic agents is common in the study of bacteria and is a problem of practical significance… 
Highly Cited
1969
Highly Cited
1969
Inhibition of uncoating of fowl plague virus by l-adamantanamine hydrochloride.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)