Skip to search formSkip to main contentSkip to account menu

Alanine-tRNA Ligase

Known as: Alanine tRNA Ligase, Ala-tRNA Ligase, Alanyl tRNA Synthetase 
An enzyme that activates alanine with its specific transfer RNA. EC 6.1.1.7.
National Institutes of Health

Related topics

Related topics

9 relations
AARS geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (1)

Charcot-Marie-Tooth Disease, Axonal, Type 2n

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Identification of the UDP-MurNAc-Pentapeptide:l-Alanine Ligase for Synthesis of Branched Peptidoglycan Precursors in Enterococcus faecalis
ABSTRACT Many species of gram-positive bacteria produce branched peptidoglycan precursors resulting from the transfer of variousl… 
2000
2000
Mapping contacts between Escherichia coli alanyl tRNA synthetase and 2' hydroxyls using a complete tRNA molecule.
A dual-specific derivative of yeast tRNA(Phe) is described whose features facilitate structure-function studies of tRNAs. This… 
Highly Cited
1999
Highly Cited
1999
Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G.U wobble base pair at 1.16 A resolution.
The acceptor stem of Escherichia coli tRNA(Ala), rGGGGCUA.rUAGCUCC (ALAwt), contains the main identity element for the correct… 
1999
1999
Correlation of deformability at a tRNA recognition site and aminoacylation specificity.
The fidelity of protein synthesis depends on specific tRNA aminoacylation by aminoacyl-tRNA synthetase enzymes, which in turn… 
Highly Cited
1996
Highly Cited
1996
A single base change prevents import of cytosolic tRNA(Ala) into mitochondria in transgenic plants.
Plant mitochondria do not contain a full set of tRNA genes, and the additional tRNAs needed for protein synthesis (including tRNA… 
1995
1995
Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen.
Because of variations in tRNA sequences in evolution, tRNA synthetases either do not acylate their cognate tRNAs from other… 
Highly Cited
1991
Highly Cited
1991
X-ray crystallographic conformational study of 5'-O-[N-(L-alanyl)-sulfamoyl]adenosine, a substrate analogue for alanyl-tRNA synthetase.
Highly Cited
1989
Highly Cited
1989
Evidence that the 3' end of a tRNA binds to a site in the adenylate synthesis domain of an aminoacyl-tRNA synthetase.
Aminoacylation requires that an enzyme-bound aminoacyladenylate is brought proximal to the 3' end of a specific transfer RNA. In… 
Highly Cited
1986
Highly Cited
1986
Overproduction and purification of the B2 subunit of ribonucleotide reductase from Escherichia coli.
1975
1975
Genetic position and amino acid replacements of several mutations in ribosomal protein S5 from Escherichia coli
SummaryThe relative genetic position of the following four mutations of ribosomal protein S5 has been determined: spc-13, a… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)