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Ribosomal proteins. VII. Two-dimensional polyacrylamide gel electrophoresis for fingerprinting of ribosomal proteins.
A two-dimensional polyacrylamide gel system has been developed, improving the analytical separation of complex protein mixtures as obtained from ribosomes. An equipment is described in detail (Figs.Expand
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Ribosomal proteins
SummaryProtein S5 which is known to confer sensitivity to the antibiotic spectinomycin has been isolated from 30S subunits of two spectinomycin-resistant mutants. By comparative amino acid analysesExpand
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Ribosomal proteins. 33. Location of amino-acid replacements in protein S12 isolated from Escherichia coli mutants resistant to streptomycin.
Abstract Ribosomal protein S12, the protein coded by the strA ciatron, was isolated from nine streptomycin-resistant mutants originating from various Escherichia coli strains. Analysis of the trypticExpand
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Architecture of prokaryotic ribosomes.
  • H. Wittmann
  • Biology, Medicine
  • Annual review of biochemistry
  • 1983
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Biochemical and genetic studies on two different types of erythromycin resistant mutants of Escherichia coli with altered ribosomal proteins
SummaryRibosomes from nine E. coli mutants with high level resistance to the antibiotic erythromycin were isolated and their proteins were compared with those of the parental strains byExpand
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Ribosomal proteins. XII. Number of proteins in small and large ribosomal subunits of Escherichia coli as determined by two-dimensional gel electrophoresis.
Two-dimensional gel electrophoresis separates all of the component proteins of the ribosomal subunits of Escherichia coli. This method shows 21 proteins in the 30S, and 34 proteins in the 50S,Expand
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Components of bacterial ribosomes.
  • H. Wittmann
  • Chemistry, Medicine
  • Annual review of biochemistry
  • 1982
PERSPECTIVES AND SUMMARY . ...... ..... . .... ..... ..... ...... 155 RIBOSOMAL PROTEINS ....... ......... ...... ... .... ..... ..... . ..... . .... ... . . ......... . .. .. .. ....... 156 PrimaryExpand
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A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstruction.
A better understanding of the molecular mechanism of protein biosynthesis depends on the availability of a reliable model for the ribosome particle. The application of a diffraction technique,Expand
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Publisher Summary A detailed knowledge of the structure of ribosomes is a prerequisite for an understanding at the molecular level of the processes taking place during protein biosynthesis. BacterialExpand
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Ribosomal proteins: their structure and spatial arrangement in prokaryotic ribosomes.
During the last 15 years of ribosomal protein study, enormous progress has been made. Each of the proteins from E. coli ribosomes has been isolated, sequenced, and immunologically and physicallyExpand
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