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AARS gene

Known as: alanine tRNA ligase 1, cytoplasmic, AARS, ALANYL-tRNA SYNTHETASE 
 
National Institutes of Health

Related topics

Related topics

2 relations
AARS2 geneAlanine-tRNA Ligase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid
Hundreds of non-proteinogenic (np) amino acids (AA) are found in plants and can in principle enter human protein synthesis… Expand
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2017
2017
Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS
Strict L-chiral rejection through Gly-cisPro motif during chiral proofreading underlies the inability of D-aminoacyl-tRNA… Expand
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Highly Cited
2014
Highly Cited
2014
Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy
Significance Misfolded proteins are a hallmark of diverse human cardiac disorders including desmin-related cardiomyopathy and… Expand
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2011
2011
Mistranslation and its control by tRNA synthetases
  • P. Schimmel
  • Philosophical Transactions of the Royal Society B…
  • 2011
    • Corpus ID: 2826691
Aminoacyl tRNA synthetases are ancient proteins that interpret the genetic material in all life forms. They are thought to have… Expand
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Review
2011
Review
2011
Multilevel populations and the evolution of antibiotic resistance through horizontal gene transfer.
Horizontal gene transfer (HGT) can create diversity in the genetic repertoire of a lineage. Successful gene transfer likely… Expand
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Highly Cited
2009
Highly Cited
2009
Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma
Mistranslation arising from confusion of serine for alanine by alanyl-tRNA synthetases (AlaRSs) has profound functional… Expand
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2009
2009
Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization
Alanyl-tRNA synthetase (AlaRS) specifically recognizes the major identity determinant, the G3:U70 base pair, in the acceptor stem… Expand
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Highly Cited
2003
Highly Cited
2003
Elucidation of tRNA‐dependent editing by a class II tRNA synthetase and significance for cell viability
Editing of misactivated amino acids by class I tRNA synthetases is encoded by a specialized internal domain specific to class I… Expand
1991
1991
A model of the alar ligaments of the upper cervical spine in axial rotation.
Although there are seven vertebrae in the human cervical spine, over 50% of the total axial rotation occurs between the first and… Expand
1962
1962
EFFECTS OF REDUCED OXYGEN TENSION ON VASCULAR PLANTS, IV. WINTER RYE GERMINATION UNDER NEAR-MARTIAN CONDITIONS AND IN OTHER NONTERRESTRIAL ENVIRONMENTS.
The existence of life under nonterrestrial conditions has been a subject of extended literary and scientific interest. Astronomy… Expand
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