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AARS gene
Known as:
alanine tRNA ligase 1, cytoplasmic
, AARS
, ALANYL-tRNA SYNTHETASE
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National Institutes of Health
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Related topics
Related topics
2 relations
AARS2 gene
Alanine-tRNA Ligase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid
Young-Hwan Song
,
Huihao Zhou
,
+8 authors
P. Schimmel
Nature Communications
2017
Corpus ID: 1671534
Hundreds of non-proteinogenic (np) amino acids (AA) are found in plants and can in principle enter human protein synthesis…
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2017
2017
Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS
K. Pawar
,
K. Suma
,
+4 authors
R. Sankaranarayanan
eLife
2017
Corpus ID: 3466064
Strict L-chiral rejection through Gly-cisPro motif during chiral proofreading underlies the inability of D-aminoacyl-tRNA…
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Highly Cited
2014
Highly Cited
2014
Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy
Ye Liu
,
J. Satz
,
M. Vo
,
L. Nangle
,
P. Schimmel
,
S. Ackerman
Proceedings of the National Academy of Sciences
2014
Corpus ID: 205271572
Significance Misfolded proteins are a hallmark of diverse human cardiac disorders including desmin-related cardiomyopathy and…
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2011
2011
Mistranslation and its control by tRNA synthetases
P. Schimmel
Philosophical Transactions of the Royal Society B…
2011
Corpus ID: 2826691
Aminoacyl tRNA synthetases are ancient proteins that interpret the genetic material in all life forms. They are thought to have…
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Review
2011
Review
2011
Multilevel populations and the evolution of antibiotic resistance through horizontal gene transfer.
Cheryl P. Andam
,
G. Fournier
,
J. Gogarten
FEMS Microbiology Reviews
2011
Corpus ID: 23304762
Horizontal gene transfer (HGT) can create diversity in the genetic repertoire of a lineage. Successful gene transfer likely…
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Highly Cited
2009
Highly Cited
2009
Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma
M. Guo
,
Y. Chong
,
Ryan Shapiro
,
K. Beebe
,
Xiang-Lei Yang
,
P. Schimmel
Nature
2009
Corpus ID: 4347573
Mistranslation arising from confusion of serine for alanine by alanyl-tRNA synthetases (AlaRSs) has profound functional…
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2009
2009
Unique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerization
M. Naganuma
,
S. Sekine
,
R. Fukunaga
,
S. Yokoyama
Proceedings of the National Academy of Sciences
2009
Corpus ID: 2888145
Alanyl-tRNA synthetase (AlaRS) specifically recognizes the major identity determinant, the G3:U70 base pair, in the acceptor stem…
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Highly Cited
2003
Highly Cited
2003
Elucidation of tRNA‐dependent editing by a class II tRNA synthetase and significance for cell viability
K. Beebe
,
L. R. de Pouplana
,
P. Schimmel
EMBO Journal
2003
Corpus ID: 28846800
Editing of misactivated amino acids by class I tRNA synthetases is encoded by a specialized internal domain specific to class I…
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Highly Cited
1991
Highly Cited
1991
A model of the alar ligaments of the upper cervical spine in axial rotation.
J. Crisco
,
M. Panjabi
,
J. Dvořák
Journal of Biomechanics
1991
Corpus ID: 28680207
1962
1962
EFFECTS OF REDUCED OXYGEN TENSION ON VASCULAR PLANTS, IV. WINTER RYE GERMINATION UNDER NEAR-MARTIAN CONDITIONS AND IN OTHER NONTERRESTRIAL ENVIRONMENTS.
S. Siegel
,
L. Rosen
,
C. Giumarro
Proceedings of the National Academy of Sciences…
1962
Corpus ID: 7497277
The existence of life under nonterrestrial conditions has been a subject of extended literary and scientific interest. Astronomy…
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