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Adenosine Receptor A3, human
Known as:
Adenosine A3 Receptor
, Adenosine Receptor A3
, ADORA3
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Adenosine receptor A3 (318 aa, ~36 kDa) is encoded by the human ADORA3 gene. This protein plays a role in G protein-coupled receptor signaling.
National Institutes of Health
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Related topics
Related topics
12 relations
ADORA3 gene
G Protein-Coupled Receptor Genes
G Protein-Coupled Receptor Signaling
Integral Membrane Proteins
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Broader (1)
Adenosine A3 Receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Pharmacological and therapeutic effects of A3 adenosine receptor agonists.
P. Fishman
,
S. Bar‐Yehuda
,
B. Liang
,
K. Jacobson
Drug Discovery Today
2012
Corpus ID: 13789280
Highly Cited
2006
Highly Cited
2006
Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation
Xiulan Zhang
,
Mei Zhang
,
A. Laties
,
C. Mitchell
Journal of Neurochemistry
2006
Corpus ID: 25858436
The purines ATP and adenosine can act as a coordinated team of transmitters. As extracellular adenosine is frequently derived…
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Review
2000
Review
2000
The role of receptor structure in determining adenosine receptor activity.
M. Olah
,
G. Stiles
Pharmacology and Therapeutics
2000
Corpus ID: 988728
Highly Cited
1997
Highly Cited
1997
Adenosine A3 receptor expression and function in eosinophils.
Blair Walker
,
Marlene A. Jacobson
,
+4 authors
Tony R. Bai
American Journal of Respiratory Cell and…
1997
Corpus ID: 177543
The A3 adenosine receptor is widely expressed in human tissues with the most abundant expression in the lung and liver, but the…
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Highly Cited
1997
Highly Cited
1997
Activation of Hippocampal Adenosine A3 Receptors Produces a Desensitization of A1 Receptor-Mediated Responses in Rat Hippocampus
T. Dunwiddie
,
L. Diao
,
H. Kim
,
Ji-long Jiang
,
K. Jacobson
Journal of Neuroscience
1997
Corpus ID: 2098858
The adenosine A3 receptor is expressed in brain, but the consequences of activation of this receptor on electrophysiological…
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Highly Cited
1995
Highly Cited
1995
Differential Interaction with and Regulation of Multiple G-proteins by the Rat A3 Adenosine Receptor (*)
T. Palmer
,
T. Gettys
,
G. Stiles
Journal of Biological Chemistry
1995
Corpus ID: 36964507
Interaction of the rat A3 adenosine receptor (A3AR) with G-proteins has been assessed using a stably transfected Chinese hamster…
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Highly Cited
1994
Highly Cited
1994
A binding site model and structure-activity relationships for the rat A3 adenosine receptor.
P. V. Galen
,
A. V. Bergen
,
+5 authors
Kenneth A. Jacobson
Molecular Pharmacology
1994
Corpus ID: 13762863
A novel adenosine receptor, the A3 receptor, has recently been cloned. We have systematically investigated the hitherto largely…
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Highly Cited
1993
Highly Cited
1993
Molecular cloning and characterization of the human A3 adenosine receptor.
C. Salvatore
,
M. Jacobson
,
Heidi E. TAYLORt
,
Joel
,
Lindeno
,
Robert G. Johnson
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 24594336
The human A3 adenosine receptor was cloned from a striatal cDNA library using a probe derived from the homologous rat sequence…
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Highly Cited
1993
Highly Cited
1993
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells.
V. Ramkumar
,
G. Stiles
,
M. Beaven
,
H. Ali
Journal of Biological Chemistry
1993
Corpus ID: 43346732
Mast cells release the mediators of the immediate hypersensitivity reaction. Adenosine is known to modulate this process, but the…
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Highly Cited
1992
Highly Cited
1992
Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.
Q. Zhou
,
Chuanyu Li
,
M. Olah
,
Robert A. Johnson
,
G. Stiles
,
O. Civelli
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 9506229
We have previously reported the selective amplification of several rat striatal cDNA sequences that encode guanine nucleotide…
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