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Adenosine Receptor A3, human
Known as:
Adenosine A3 Receptor
, Adenosine Receptor A3
, ADORA3
Â
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Adenosine receptor A3 (318 aa, ~36 kDa) is encoded by the human ADORA3 gene. This protein plays a role in G protein-coupled receptor signaling.
Topic mentions per year
Topic mentions per year
1993-2017
0
10
20
1993
2017
Related topics
Related topics
12 relations
ADORA3 gene
G Protein-Coupled Receptor Genes
G Protein-Coupled Receptor Signaling
Integral Membrane Proteins
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Broader (1)
Adenosine A3 Receptor
Related mentions per year
Related mentions per year
1946-2018
1940
1960
1980
2000
2020
Adenosine Receptor A3, human
Signal Transduction
Receptors, Purinergic P1
Receptors, Cell Surface
G Protein-Coupled Receptor Genes
Receptor Gene
Papers overview
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2010
2010
Glucocorticoids promote survival of anti-inflammatory macrophages via stimulation of adenosine receptor A3.
Katarzyna Barczyk
,
Jan Mauno Ehrchen
,
+4 authors
Johannes Roth
Blood
2010
Active resolution of inflammation is a previously unrecognized process essential for tissue homeostasis. Monocytes play a pivotal…Â
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2005
2005
Antiinflammatory effect of A3 adenosine receptor agonists in murine autoimmune arthritis models.
Ehud Baharav
,
Sara Bar-Yehuda
,
+6 authors
Pnina Fishman
The Journal of rheumatology
2005
OBJECTIVE CF101, an A3 adenosine receptor (A3AR) agonist, is a small orally bioavailable molecule known to suppress in vitro the…Â
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2003
2003
A3 adenosine receptor activation in melanoma cells: association between receptor fate and tumor growth inhibition.
Lea Madi
,
Sara Bar-Yehuda
,
Faina Barer
,
Eti Ardon
,
Avivit Ochaion
,
Pnina Fishman
The Journal of biological chemistry
2003
Activation of the Gi protein-coupled A3 adenosine receptor (A3AR) has been implicated in the inhibition of melanoma cell growth…Â
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2002
2002
Knockout of A3 adenosine receptors reduces mouse intraocular pressure.
Marcel Y. Avila
,
Richard A. Stone
,
Mortimer M. Civan
Investigative ophthalmology & visual science
2002
PURPOSE To test the putative role of A(3) adenosine receptors (ARs) in modulating intraocular pressure (IOP). METHODS IOP was…Â
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2002
2002
Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor.
Richard J. Black
,
Yiru Guo
,
+5 authors
John A. Auchampach
Circulation research
2002
We used a genetic approach to determine whether increasing the level of A3 adenosine receptors (A3ARs) expressed in the heart…Â
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Highly Cited
2000
Highly Cited
2000
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells.
Carmela Salvatore
,
Simon Tilley
,
Anne M. Latour
,
Daniel S. Fletcher
,
Bruno Koller
,
Mireille Jacobson
The Journal of biological chemistry
2000
The A(3) adenosine receptor (A3AR) is one of four receptor subtypes for adenosine and is expressed in a broad spectrum of tissues…Â
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2000
2000
Are A3 adenosine receptors expressed in the brain?
Scott A. Rivkees
,
Sundararajah Thevananther
,
H. Hao
Neuroreport
2000
An increasing number of reports suggest a role for A3 adenosine receptors (A3ARs) in mediating adenosine action in the central…Â
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Highly Cited
1997
Highly Cited
1997
Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor.
John A. Auchampach
,
X. Jin
,
T. C. Wan
,
G. H. Caughey
,
Judith A Linden
Molecular pharmacology
1997
We cloned and characterized the canine A3 adenosine receptor (AR) and examined AR-induced degranulation of the BR line of canine…Â
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Highly Cited
1997
Highly Cited
1997
Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation.
X. Jin
,
R. K. Shepherd
,
Brian R. Duling
,
Judith A Linden
The Journal of clinical investigation
1997
We investigated the mechanism by which inosine, a metabolite of adenosine that accumulates to > 1 mM levels in ischemic tissues…Â
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Highly Cited
1993
Highly Cited
1993
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells.
V. Ramkumar
,
Gary L. Stiles
,
Michael A. Beaven
,
H. Ali
The Journal of biological chemistry
1993
Mast cells release the mediators of the immediate hypersensitivity reaction. Adenosine is known to modulate this process, but the…Â
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