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Adenosine Receptor A3, human

Known as: Adenosine A3 Receptor, Adenosine Receptor A3, ADORA3 
Adenosine receptor A3 (318 aa, ~36 kDa) is encoded by the human ADORA3 gene. This protein plays a role in G protein-coupled receptor signaling.
National Institutes of Health

Related topics

Related topics

12 relations
ADORA3 geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane Proteins
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Broader (1)

Adenosine A3 Receptor

Papers overview

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Review
2012
Review
2012
Pharmacological and therapeutic effects of A3 adenosine receptor agonists.
The A(3) adenosine receptor (A(3)AR) coupled to G(i) (inhibitory regulative guanine nucleotide-binding protein) mediates anti… Expand
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Highly Cited
2008
Highly Cited
2008
Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial.
OBJECTIVE Adenosine exerts antiinflammatory effects via activation of the A3 adenosine receptor (A3AR), a Gi protein-associated… Expand
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Highly Cited
2005
Highly Cited
2005
Analysis and visualization of tree space.
We explored the use of multidimensional scaling (MDS) of tree-to-tree pairwise distances to visualize the relationships among… Expand
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Highly Cited
2005
Highly Cited
2005
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.
The effect of adenosine and its analogues on the cytotoxic activity of IL-2-activated NK cells was investigated. Adenosine is an… Expand
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Review
1998
Review
1998
Adenosine A3 receptors: novel ligands and paradoxical effects.
The physiological role of the adenosine A3 receptor is being investigated using newly synthesized, selective ligands. Recently… Expand
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Highly Cited
1997
Highly Cited
1997
Adenosine A3 receptor expression and function in eosinophils.
The A3 adenosine receptor is widely expressed in human tissues with the most abundant expression in the lung and liver, but the… Expand
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Highly Cited
1997
Highly Cited
1997
Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor.
We cloned and characterized the canine A3 adenosine receptor (AR) and examined AR-induced degranulation of the BR line of canine… Expand
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Highly Cited
1993
Highly Cited
1993
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells.
Mast cells release the mediators of the immediate hypersensitivity reaction. Adenosine is known to modulate this process, but the… Expand
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Highly Cited
1993
Highly Cited
1993
Molecular cloning and characterization of the human A3 adenosine receptor.
The human A3 adenosine receptor was cloned from a striatal cDNA library using a probe derived from the homologous rat sequence… Expand
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Highly Cited
1992
Highly Cited
1992
Molecular cloning and characterization of an adenosine receptor: the A3 adenosine receptor.
We have previously reported the selective amplification of several rat striatal cDNA sequences that encode guanine nucleotide… Expand
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