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- Publications
- Influence
NF-kappaB functions as a tumour promoter in inflammation-associated cancer.
- E. Pikarsky, R. Porat, +7 authors Y. Ben-Neriah
- Medicine
- Nature
- 2004
The causes of sporadic human cancer are seldom recognized, but it is estimated that carcinogen exposure and chronic inflammation are two important underlying conditions for tumour development, the… Expand
Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness.
- S. Beyth, Z. Borovsky, +5 authors J. Rachmilewitz
- Medicine, Biology
- Blood
- 1 March 2005
Infusion of either embryonic or mesenchymal stem cells prolongs the survival of organ transplants derived from stem cell donors and prevents graft-versus-host-disease (GVHD). An in-depth mechanistic… Expand
NF-κB functions as a tumour promoter in inflammation-associated cancer
- E. Pikarsky, R. Porat, +7 authors Y. Ben-Neriah
- Biology
- Nature
- 23 September 2004
The causes of sporadic human cancer are seldom recognized, but it is estimated that carcinogen exposure and chronic inflammation are two important underlying conditions for tumour development, the… Expand
The H19 Non-Coding RNA Is Essential for Human Tumor Growth
- Imad J. Matouk, N. Degroot, +4 authors E. Galun
- Biology, Medicine
- PloS one
- 5 September 2007
Background Mutations and epigenetic aberrant signaling of growth factors pathways contribute to carcinogenesis. Recent studies reveal that non-coding RNAs are controllers of gene expression. H19 is… Expand
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
- M. Darash-Yahana, E. Pikarsky, +8 authors A. Peled
- Medicine
- FASEB journal : official publication of the…
- 1 August 2004
Hormone refractory metastatic prostate cancer remains an incurable disease. We found that high expression levels of the chemokine receptor CXCR4 correlated with the presence of metastatic disease in… Expand
Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme.
- A. Freeman, Z. Zakay-Rones, +9 authors T. Siegal
- Medicine
- Molecular therapy : the journal of the American…
- 2006
We undertook a Phase I/II trial in patients with apparent recurrent glioblastoma multiforme (GBM) based on imaging studies to determine the safety and tumor response of repetitive intravenous… Expand
Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis
- Imad J. Matouk, I. Abbasi, A. Hochberg, E. Galun, H. Dweik, M. Akkawi
- Medicine
- European journal of gastroenterology & hepatology
- 1 June 2009
Background The highly upregulated in liver cancer (HULC) gene transcribes to an mRNA-like noncoding RNA (ncRNA) by the RNA polymerase II and processed by capping, splicing and polyadenylation. It is… Expand
Mutant KRAS is a druggable target for pancreatic cancer
- Elina Zorde Khvalevsky, R. Gabai, +22 authors E. Galun
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 2 December 2013
Significance Pancreatic cancer is still one of the major challenges in clinical oncology. Mutant KRAS is a driving oncogene in the majority of human pancreatic cancer cases. We have made an effort to… Expand
The oncofetal H19 RNA connection: hypoxia, p53 and cancer.
- Imad J. Matouk, S. Mezan, +6 authors A. Hochberg
- Biology, Medicine
- Biochimica et biophysica acta
- 1 April 2010
Expression of the imprinted H19 gene is remarkably elevated in a large number of human cancers. Recently, we reported that H19 RNA is up-regulated in hypoxic stress and furthermore, it possesses… Expand
IL-6/IL-6R axis plays a critical role in acute kidney injury.
- Yael Nechemia-Arbely, D. Barkan, +4 authors J. Axelrod
- Medicine
- Journal of the American Society of Nephrology…
- 1 June 2008
The response to tissue injury involves the coordination of inflammatory and repair processes. IL-6 expression correlates with the onset and severity of acute kidney injury (AKI), but its contribution… Expand
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