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AZD7451

Known as: TRK Inhibitor AZD7451, Tropomyosin Receptor Kinase Inhibitor AZD7451 
A tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity. AZD7451 binds to TRK, thereby preventing the neurotrophin-TRK… Expand
National Institutes of Health

Papers overview

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2019
2019
The present study was aimed to investigate the role and mechanism of neurotrophin-3 (NT-3) and its specific receptor tropomyosin… Expand
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2018
2018
Analysis of cyclophosphamide (CP) and its metabolite, 4-hydroxycyclophosphamide (4OHCP), in a single assay has the ability to… Expand
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2014
2014
Advances in the molecular segmentation of lung cancer has raised the possibility that neurotrophic tyrosine kinase receptor (NTRK… Expand
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2014
2014
BACKGROUND: We have shown that inhibition of TrkA both genetically and pharmacologically results in profound inhibition of glioma… Expand
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Highly Cited
2013
Highly Cited
2013
Treatment options for adenoid cystic carcinoma (ACC) of the salivary gland, a slowly growing tumor with propensity for… Expand
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2013
2013
Tropomyosin-related kinases (Trk) are tyrosine kinase receptors implicated in tumor proliferation, invasion, and survival… Expand
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