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ALOX5 gene

Known as: ARACHIDONATE 5-LIPOXYGENASE, 5-LOX, ALOX5 
This gene plays a role in inflammation.
National Institutes of Health

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ALOX5 wt Allele
Arachidonate 5-LipoxygenaseLipid MetabolismOxidation-Reductioninflammatory response

Papers overview

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2015
2015
The association between vitamin D and the arachidonate 5-lipoxygenase (ALOX-5) gene polymorphism in type 2 diabetes
2012
2012
Association of ALOX5AP with ischemic stroke in eastern Chinese.
BACKGROUND 5-lipoxygenase protein (ALOX5AP) has been recognized as a susceptibility gene for stroke and coronary artery diseases… 
2011
2011
5-Lipoxygenase Activating Protein Gene Variants and Coronary Heart Disease: A SNP Association Study
Objective The aim of this study was to explore the role of variants of gene encoding arachidonate 5- lipoxygenase-activating… 
2009
2009
[Omega-3 polyunsaturated fatty acids stimulate the expression of PPAR target genes].
In experiments on isolated neonatal cardiomyocytes and hearts of adult rats we investigated the influence of polyunsaturated… 
2009
2009
The Aryl Hydrocarbon Receptor Activator Benzo [ a ] pyrene Enhances Vitamin D 3 Catabolism in Macrophages
Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon produced by cigarette combustion, is implicated as a causative agent in… 
2007
2007
Leukotriene B 4 production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with risk of myocardial infarction
Leukotrienes are implicated in the pathogenesis of coronary artery disease. Recently two haplotypes (Hap A and Hap B) in the gene… 
2005
2005
Pharmacogenomics and the Drug Discovery Pipeline
One of the key factors in developing improved medicines lies in understanding the molecular basis of the complex diseases we… 
2002
2002
Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis
5-LO is expressed in monocytes / macrophages (mono / mac) and foam cells atherosclerotic lesions, in the CAST mice and CON6 mice… 
1993
1993
High Current Density Contacts for GaAs Photoconductive Semiconductor Switches
The current densities implied by current filaments in GaAs photoconductive semiconductor switches (PCSS) are in excess of 1 MA/cm… 
1991
1991
Selective 5‐Lipoxygenase Inhibitor BW A4C Does Not Influence Progression of Tissue Injury in a Canine Model of Regional Myocardial Ischaemia and Reperfusion
The effects of BW A4C, a selective arachidonate 5-lipoxygenase (5-LO) inhibitor, on the progression of myocardial tissue injury…