ALOX5 gene

Known as: ARACHIDONATE 5-LIPOXYGENASE, 5-LOX, ALOX5 
This gene plays a role in inflammation.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Targeting of cancer stem cells is believed to be essential for curative therapy of cancers, but supporting evidence is limited… (More)
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2009
2009
Cancer stem cells (CSCs) are believed to be the initiating cells for many types of blood cancer and some solid tumors, and… (More)
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2008
2008
The 5-lipoxygenase (ALOX5)-derived lipid mediators leukotrienes and lipoxins have regulatory functions in inflammation by… (More)
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Review
2006
Review
2006
Anthropological and epidemiological studies and studies at the molecular level indicate that human beings evolved on a diet with… (More)
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Highly Cited
2005
Highly Cited
2005
Previous studies indicate that the arachidonic acid-metabolizing enzymes COX-2 and 5-LOX are overexpressed during the process of… (More)
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Highly Cited
2005
Highly Cited
2005
Forward genetic approaches to identify genes involved in complex traits such as common human diseases have met with limited… (More)
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Highly Cited
2004
Highly Cited
2004
We mapped a gene predisposing to myocardial infarction to a locus on chromosome 13q12–13. A four-marker single-nucleotide… (More)
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Review
2003
Review
2003
Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both… (More)
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Highly Cited
1999
Highly Cited
1999
Clinically similar asthma patients may develop airway obstruction by different mechanisms. Asthma treatments that specifically… (More)
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Highly Cited
1992
Highly Cited
1992
The rhizomes of Zingiber officinale (ginger) and Alpinia officinarum contain potent inhibitors against prostaglandin… (More)
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