ALOX5 wt Allele

Known as: 5LPG, RP11-67C2.3, MGC163204 
Human ALOX5 wild-type allele is located in the vicinity of 10q11.2 and is approximately 72 kb in length. This allele, which encodes arachidonate 5… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2014
02419902014

Papers overview

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2014
2014
OBJECTIVE The impact of leukotriene production by the 5-lipoxygenase (5-LO) pathway in the pathophysiology of abdominal aortic… (More)
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2014
2014
The roles of eosinophils in antimicrobial defense remain incompletely understood. In ovalbumin-sensitized mice, eosinophils are… (More)
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2014
2014
This study investigated the localization of critical enzymes involved in arachidonic acid metabolism during the initial and… (More)
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2011
2011
Hugo: ALOX5 Other names: 5-LO; EC 1.13.11.34; leukotriene A4 synthase; 5LPG; LOG5 Location: 10q11.2 Local order: Genes flanking… (More)
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2010
2010
BACKGROUND AND PURPOSE Cyclooxygenase-2 (COX-2) promotes inflammation by synthesizing pro-inflammatory prostaglandins from… (More)
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2009
2009
The cerebral ischemia-reperfusion injury remains a major medical problem due to the lack of effective treatment. The mechanism of… (More)
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2003
2003
The enzyme 5-lipoxygenase (5-LO) initiates the synthesis of leukotrienes from arachidonic acid. In resting cells, 5-LO can… (More)
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1999
1999
Leukotrienes (LT) are mediators derived from the 5-lipoxygenase (5-LO) pathway, which play a role in host defense, and are… (More)
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1998
1998
5-Lipoxygenase (5-LO; arachidonate:oxygen 5-oxidoreductase, EC 1.13.11.34) is the enzyme responsible for the first step in the… (More)
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1990
1990
The present study was undertaken to investigate the changes in arachidonic acid (AA) metabolism which accompany rat macrophage (m… (More)
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