ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study

@article{Girelli2007ALOX5APGV,
  title={ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study},
  author={Domenico Girelli and Nicola I Martinelli and Elisabetta Trabetti and Oliviero Olivieri and Ugo Cavallari and Giovanni Malerba and Fabiana Busti and Simonetta Friso and Francesca Pizzolo and Pier Franco Pignatti and Roberto Corrocher},
  journal={European Journal of Human Genetics},
  year={2007},
  volume={15},
  pages={959-966}
}
The aim of this study was to explore the role of variants of the gene encoding arachidonate 5-lipoxygenase-activating protein (ALOX5AP) as possible susceptibility factors for coronary artery disease (CAD) and myocardial infarction (MI) in patients with or without angiographically proven CAD. A total of 1431 patients with or without angiographically documented CAD were examined simultaneously for seven ALOX5AP single-nucleotide polymorphisms, allowing reconstruction of the at-risk haplotypes… CONTINUE READING

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