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AKR1D1 gene

Known as: ALDO-KETO REDUCTASE FAMILY 1, MEMBER D1, 5-BETA-REDUCTASE, delta 4-3-ketosteroid-5-beta-reductase 
National Institutes of Health

Related topics

Related topics

1 relation
cholestenone 5 beta-reductase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Screening of significant biomarkers related with prognosis of liver cancer by lncRNA‐associated ceRNAs analysis
This study aimed to identify significant biomarkers related to the prognosis of liver cancer using long noncoding RNA (lncRNA… 
2019
2019
Differential regulation of 5[beta]-reductase (AKR1D1) expression and activity by glucocorticoids in human and rodent liver
2017
2017
Circulating Biomarkers for Predicting Infliximab Response in Rheumatoid Arthritis: A Systematic Bioinformatics Analysis
Background Infliximab shows good efficacy in treating refractory rheumatoid arthritis (RA). However, many patients responded… 
2016
2016
5[beta]-reductase (AKR1D1) is a regulator of glucose homeostasis in human hepatocytes and development of model systems to define its role in metabolic liver disease
2015
2015
Model systems to define the role of AKR1D1 in metabolic liver disease
Non-alcoholic fatty liver disease is the hepatic manifestation of the global epidemic of metabolic disease. It is tightly… 
2011
2011
The effect of disease associated point mutations on 5β-reductase (AKR1D1) enzyme function.
2009
2009
Characterization of the human CREB3L2 gene promoter.
CREB3L2 encodes a member of the CREB3 family of transcription factors. We characterized its promoter region, showing that it is… 
2008
2008
A new susceptibility locus for hypospadias on chromosome 7q32.2-q36.1
Hypospadias is a common malformation (1/300 boys) where the urethra opens on the ventral side of the penis. It is considered a… 
2008
2008
Crystal Structure of Human Liver 4-3-Ketosteroid 5-Reductase ( AKR 1 D 1 ) and Implications for Substrate Binding and Catalysis *
AKR1D1 (steroid 5 -reductase) reduces all 4-3-ketosteroids to form 5 -dihydrosteroids, a first step in the clearance of steroid… 
2004
2004
P0188 SRD5B1 (AKR1D1) GENE ANALYSIS IN DELTA4–3‐OXOSTEROID 5BETA‐REDUCTASE DEFICIENCY: EVIDENCE FOR PRIMARY GENETIC DEFECT
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