AKR1D1 gene

Known as: ALDO-KETO REDUCTASE FAMILY 1, MEMBER D1, 5-BETA-REDUCTASE, delta 4-3-ketosteroid-5-beta-reductase 
 

Topic mentions per year

Topic mentions per year

1999-2016
024619992016

Papers overview

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2014
2014
Human AKR1D1 (steroid 5β-reductase/aldo-keto reductase 1D1) catalyses the stereospecific reduction of double bonds in Δ4-3… (More)
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2013
2013
Human liver gene regulatory (Bayesian) network analysis was previously used to identify a cytochrome P450 (P450) gene subnetwork… (More)
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2011
2011
Active sex hormones such as testosterone and progesterone are metabolized to tetrahydrosteroids in the liver to terminate hormone… (More)
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2011
2011
Human steroid 5β-reductase (aldo-keto reductase 1D1) catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double… (More)
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2011
2011
The stereospecific 5β-reduction of Δ(4)-3-ketosterols is very difficult to achieve chemically and introduces a 90° bend between… (More)
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2010
2010
Bile acid deficiency is a serious syndrome in newborns that can result in death if untreated. 5beta-Reductase deficiency is one… (More)
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2008
2008
Conclusive in vivo evidence regarding the enzyme responsible for steroid hormone 5beta-reduction has not been obtained, although… (More)
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2008
2008
The 5beta-reductases (AKR1D1-3) are unique enzymes able to catalyze efficiently and in a stereospecific manner the 5beta… (More)
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2003
2003
Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or… (More)
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2003
2003
BACKGROUND A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids… (More)
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