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AK 2123

Known as: 1H-1,2,4-Triazole-1-acetamide, N-(2-methoxyethyl)-3-nitro-, AK-2123 
National Institutes of Health

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3 relations

Broader (3)

Radiation-Sensitizing AgentsTriazolessenazole

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Feasibility trial for daily oral administration of the hypoxic sensitizer AK-2123 (Sanazole) in radiotherapy.
BACKGROUND To examine the feasibility of daily oral administration of the hypoxic tumor radiation sensitizer, sanazole (AK-2123… 
2007
2007
AK-2123 (Sanazol) as a radiation sensitizer in the treatment of stage III cervical cancer: results of an IAEA multicentre randomised trial.
2005
2005
Radiomodulatory effect of liposome encapsulated AK-2123 on tumor in mice exposed to hepatocarcinogen
An attempt was made to evaluate the whole body γ-radiation effect on tumor in the presence of free and liposome encapsulated AK… 
2003
2003
Radiosensitizer Sanazole (AK-2123) enhances γ-radiation-induced Apoptosis in murine fibrosarcoma
Sanazole/AK-2123/γ-Radiation/DNA damage/Apoptosis/Radiosensitizer. Sanazole (AK-2123) (N-2′-methoxy ethyl)-2-(3″-nitro-1… 
2003
2003
Radiosensitizer sanazole (AK-2123) enhances gamma-radiation-induced apoptosis in murine fibrosarcoma.
Sanazole (AK-2123) (N-2'-methoxy ethyl)-2-(3"-nitro-1"-triazolyl)acetamide, which has completed phase III clinical trials as a… 
2001
2001
Effect of a hypoxic radiosensitizer, AK 2123 (Sanazole), on yeast Saccharomyces cerevisiae.
Sanazole/DNA repair/Hypoxic radiosensitization/DNA polymerases/Saccharomyces cerevisiae Yeast Saccharomyces cerevisiae can exist… 
2000
2000
Redox reactions of sanazole (AK-2123) in aqueous solutions: a pulse radiolysis study.
The redox chemistry of sanazole, an efficient hypoxic cell radiosensitizer, generally referred to as AK-2123, was studied by… 
1996
1996
Modification of radio-thermo-chemotherapy by AK-2123 and hydralazine in tumor bearing mice.
The effects of chemical modifiers of hypoxic radiosensitizer, a 3-nitrotriazole derivative AK-2123 (200 mg/kg) before treatment… 
1996
1996
Multimodality treatment using AK-2123, hydralazine, radiation & hyperthermia on a transplantable mouse tumour.
The in vivo response of a transplantable mouse tumour, Sarcoma 180 to AK-2123 (AK), local irradiation (RT) and local hyperthermia… 
1995
1995
Radiosensitization with a 3-nitrotriazole (ak-2123).
We investigated to clarify the mechanism of action of AK-2123. V79 cells were used, and the effect of the substance was estimated… 
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