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senazole

Known as: sanazole, technetium-99m-cyclam AK 2123 
 

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1998-2018
024619982018

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AK 2123

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Related mentions per year

1986-2018
19801990200020102020
senazole
AK 2123

Papers overview

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2014
2014
Sanazole directed targeting of silver nanoparticle drug complex to tumor mass: a preclinical investigation in murine model.
AIM OF STUDY To explore sanazole (AK) directed targeting of the antineoplastic drug doxorubicin (DOX) complexed with silver… (More)
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2013
2013
Radiation enhancing effects with the combination of sanazole and irinotecan in hypoxic HeLa human cervical cancer cell line.
PURPOSE This study was conducted to determine the synergistic radiation sensitizing effects of the combination of sanazole and… (More)
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2009
2009
Enhancement of radiation-induced apoptosis of human lymphoma U937 cells by sanazole
Sanazole has been tested clinically as a hypoxic cell radiosensitizer. In this study, we determined whether sanazole enhances the… (More)
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2009
2009
Enhancement of hyperthermia-induced apoptosis by sanazole in human lymphoma U937 cells.
Sanazole has been tested clinically as a hypoxic cell radiosensitizer. The aim of the present study was to investigate whether… (More)
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2006
2006
Safety and radiosensitizing efficacy of sanazole (AK 2123) in oropharyngeal cancers: randomized controlled double blind clinical trial.
UNLABELLED Oropharynx is an important site of cancer in India. Global comparison indicates higher incidences in India… (More)
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2005
2005
Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo.
Sanazole (AK-2123, 3-nitrotriazole derivative, N1-(3-methoxypropyl)-2-(3-nitro-1 H-1,2,4-triazol-1-yl)acetamide) and nimorazole… (More)
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2004
2004
Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia.
The preparation of a polyazamacrocyclic-nitrotriazole conjugate for radiolabeling with the therapeutic radioisotope viz. (177)Lu… (More)
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2003
2003
Radiosensitizer sanazole (AK-2123) enhances gamma-radiation-induced apoptosis in murine fibrosarcoma.
Sanazole (AK-2123) (N-2'-methoxy ethyl)-2-(3"-nitro-1"-triazolyl)acetamide, which has completed phase III clinical trials as a… (More)
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2001
2001
Sanazole as substrate of xanthine oxidase and microsomal NADPH/cytochrome P450 reductase.
The influence of sanazole and metronidazole on cytochrome C (Cyt c(3+)) reduction in the enzyme systems xanthine/xanthine oxidase… (More)
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2000
2000
Redox reactions of sanazole (AK-2123) in aqueous solutions: a pulse radiolysis study.
The redox chemistry of sanazole, an efficient hypoxic cell radiosensitizer, generally referred to as AK-2123, was studied by… (More)
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