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senazole

Known as: sanazole, technetium-99m-cyclam AK 2123 
National Institutes of Health

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AK 2123

Papers overview

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2018
2018
Tumor control by hypoxia‐specific chemotargeting of iron‐oxide nanoparticle – Berberine complexes in a mouse model
2009
2009
Enhancement of radiation-induced apoptosis of human lymphoma U937 cells by sanazole
Sanazole has been tested clinically as a hypoxic cell radiosensitizer. In this study, we determined whether sanazole enhances the… 
2009
2009
Enhancement of hyperthermia-induced apoptosis by sanazole in human lymphoma U937 cells
Sanazole has been tested clinically as a hypoxic cell radiosensitizer. The aim of the present study was to investigate whether… 
2005
2005
Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo.
Sanazole (AK-2123, 3-nitrotriazole derivative, N1-(3-methoxypropyl)-2-(3-nitro-1 H-1,2,4-triazol-1-yl)acetamide) and nimorazole… 
2004
2004
Preparation and preliminary biological evaluation of a 177Lu labeled sanazole derivative for possible use in targeting tumor hypoxia.
2003
2003
Radiosensitizer Sanazole (AK-2123) enhances γ-radiation-induced Apoptosis in murine fibrosarcoma
Sanazole/AK-2123/γ-Radiation/DNA damage/Apoptosis/Radiosensitizer. Sanazole (AK-2123) (N-2′-methoxy ethyl)-2-(3″-nitro-1… 
2001
2001
Effect of a hypoxic radiosensitizer, AK 2123 (Sanazole), on yeast Saccharomyces cerevisiae.
Sanazole/DNA repair/Hypoxic radiosensitization/DNA polymerases/Saccharomyces cerevisiae Yeast Saccharomyces cerevisiae can exist… 
2000
2000
Radiation induced effect of the vitamins C, E and beta-carotene on sanazole efficiency. A study in vitro.
The effect of the vitamins C, E-acetate and beta-carotene on the sanazole (AK-2123) efficiency was investigated in vitro (E. coli… 
2000
2000
Redox reactions of sanazole (AK-2123) in aqueous solutions: a pulse radiolysis study.
The redox chemistry of sanazole, an efficient hypoxic cell radiosensitizer, generally referred to as AK-2123, was studied by… 
Review
1996
Review
1996
An overview of the initial experience with AK-2123 as a hypoxic cell sensitizer with radiation in the treatment of advanced head and neck cancers.
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