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AJ 2615

Known as: AJ-2615 
National Institutes of Health

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1 relation

Broader (1)

monatepil

Papers overview

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2001
2001
Inhibition of vasoconstriction by AJ-2615, a novel calcium antagonist with alpha(1)-adrenergic receptor blocking activity in human conduit arteries used as bypass grafts.
AIMS Graft spasm may develop during coronary artery bypass grafting and reversal of spasm is still challenging. The purpose of… 
1997
1997
Inhibitory effect of monatepil maleate on acyl-CoA:cholesterol acyltransferase activity in the liver of cholesterol-fed Japanese monkeys.
1997
1997
Simultaneous determination of a novel calcium entry blocker, monatepil maleate, and its metabolites in rat plasma by means of solid-phase extraction and reversed-phase liquid chromatography with…
1995
1995
Studies on calcium antagonistic and alpha 1-adrenergic receptor blocking activities of monatepil maleate, its metabolites and their enantiomers.
The calcium antagonistic and alpha 1-adrenergic receptor blocking activities of monatepil maleate (CAS 103377-41-9, (+/-)-N-(6,11… 
1993
1993
ANTI‐ARRHYTHMIC EFFECTS OF A NEW CALCIUM ANTAGONIST, MONOTEPIL, AJ‐2615, IN EXPERIMENTAL ARRHYTHMIC MODELS
1. To characterize the anti‐arrhythmic properties of a new calcium antagonist, monotepil, AJ‐2615, the preventive effects of AJ… 
1993
1993
Antihypertensive Effects of AJ‐2615, a New Calcium Antagonist with α1-Adrenergic Blocking Activity in Experimental Hypertensive Animals
The antihypertensive effect of AJ-2615 [(±)-N-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-fluorophenyl)-1-piperazinebutanamide… 
1992
1992
Identification of AJ-2615 and its S-oxidized metabolites in rat plasma by use of tandem-mass spectrometry.
The structural elucidation of the metabolites of a new calcium entry blocker, AJ-2615 (AJ), in rat plasma is described… 
1992
1992
Efficacy and safety of a new calcium antagonist AJ-2615 in essential hypertension
1991
1991
A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11- dihydrodibenzo[b,e]-thiepin maleate and related compounds.
A series of [(epsilon-aminoalkanoyl)amino]-6,11- dihydrodibenzo[b,e]thiepins and -5H-dibenzo[a,d]cycloheptenes and related… 
1990
1990
Determination of a novel calcium entry blocker, AJ-2615, in plasma using solid-phase extraction and high-performance liquid chromatography with electrochemical detection.
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