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monatepil

Known as: 11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleate, (+/-)-N-(6,11-Dihydrodibenzo(B,E)Thiepin-11-yl)-4-(P-Fluorophenyl)-1-Piperazinebutyramide, 1-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,e)thiepin-11-yl)-4-(4-fluorophenyl)-, (Z)-2-butenedioate (1:1) 
 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

AJ 2615monatepil maleate

Broader (5)

Adrenergic alpha-AntagonistsAntihypertensive AgentsCalcium Channel BlockersDibenzothiepins
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Papers overview

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Review
1996
Review
1996
Identifiable Achatina giant neurones: their localizations in ganglia, axonal pathways and pharmacological features.
1. An African giant snail (Achatina fulica Férussac), originally from East Africa, is now found abundantly in tropical and… Expand
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1995
1995
Relative Contribution of α1-Adrenoceptor Blocking Activity to the Hypotensive Effect of the Novel Calcium Antagonist Monatepil
Summary: Monatepil, a novel calcium antagonist, has α1-adrenoceptor blocking activity; in the present study, we examined the… Expand
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1994
1994
Noninvasive quantitative evaluation of early atherosclerosis and the effect of monatepil, a new antihypertensive agent. An interim report.
In two studies on the same group of patients we evaluated noninvasive methods of assessing atherosclerosis and determined the… Expand
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1994
1994
Up-regulation of hepatic LDL receptor gene expression by monatepil, a novel calcium antagonist, in high cholesterol diet-fed Japanese monkeys.
The action of the novel antihypertensive calcium antagonist monatepil on the hepatic LDL receptor was investigated at the gene… Expand
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1994
1994
Comparative effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic-blocking activity, and nitrendipine on lipoprotein and carbohydrate metabolism in patients with hypertension.
The effects of monatepil, a new calcium antagonist with alpha 1-blocking activity, and nitrendipine on lipoprotein and… Expand
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1994
1994
Anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed Japanese Macaca fuscata…
1. The preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-N-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4… Expand
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Review
1994
Review
1994
Antihypertensive, antiatherosclerotic, and plasma lipid-lowering effects of monatepil, a novel calcium antagonist with alpha 1-adrenoceptor-blocking activity in experimental animals.
Traditional antihypertensive therapy has been shown to reduce the incidence of hypertension-related vascular injuries; however… Expand
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1994
1994
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats.
Antianginal effects of monatepil ([(+-)-N-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-fluor ophenyl)-1-piperazinebutanamide… Expand
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1993
1993
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
Effects of monatepil ([(+/-)-N-(6,11-dihydrodibenzo[b, e]thiepin-11-yl)-4-(p-fluorophenyl)-1-piperazinebutyramide]m aleate, AJ… Expand
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1993
1993
Anti-arrhythmic effects of a new calcium antagonist, monatepil, AJ-2615, in experimental arrhythmic models [corrected].
1. To characterize the anti-arrhythmic properties of a new calcium antagonist, monatepil [corrected], AJ-2615, the preventive… Expand
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