FAQ

monatepil

Known as: 11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleate, (+/-)-N-(6,11-Dihydrodibenzo(B,E)Thiepin-11-yl)-4-(P-Fluorophenyl)-1-Piperazinebutyramide, 1-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,e)thiepin-11-yl)-4-(4-fluorophenyl)-, (Z)-2-butenedioate (1:1) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-1999
02419931999

Related topics

Related topics

7 relations

Narrower (2)

AJ 2615monatepil maleate

Broader (5)

Adrenergic alpha-AntagonistsAntihypertensive AgentsCalcium Channel BlockersDibenzothiepins
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Related mentions per year

Related mentions per year

1941-2018
19401960198020002020
monatepil
Antihypertensive Agents
Calcium Channel Blockers
Adrenergic alpha-Antagonists
Piperazines
AJ 2615

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil.
Monatepil, a novel calcium antagonist, has alpha 1-adrenoceptor blocking activity; in the present study, we examined the relative… (More)
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1995
1995
Long-lasting antagonistic effects of monatepil on Ca2+ current in guinea-pig ventricular cells.
Monatepil maleate (CAS 103377-41-9, AJ-2615), a new derivative of dihydrodibenzothiepins, showed dose-dependent inhibition of Ca2… (More)
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1994
1994
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats.
Antianginal effects of monatepil ([(+-)-N-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-fluor ophenyl)-1-piperazinebutanamide… (More)
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1994
1994
Noninvasive quantitative evaluation of early atherosclerosis and the effect of monatepil, a new antihypertensive agent. An interim report.
In two studies on the same group of patients we evaluated noninvasive methods of assessing atherosclerosis and determined the… (More)
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1994
1994
Comparative effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic-blocking activity, and nitrendipine on lipoprotein and carbohydrate metabolism in patients with hypertension.
The effects of monatepil, a new calcium antagonist with alpha 1-blocking activity, and nitrendipine on lipoprotein and… (More)
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1994
1994
Anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed Japanese Macaca fuscata…
1. The preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-N-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4… (More)
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1994
1994
The efficacy of monatepil, a new calcium antagonist, in the treatment of essential hypertension.
A multicenter, open-label trial in Japan examined the efficacy, safety, and optimal dose of monatepil (AJ-2615) as monotherapy… (More)
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1993
1993
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
Effects of monatepil ([(+/-)-N-(6,11-dihydrodibenzo[b, e]thiepin-11-yl)-4-(p-fluorophenyl)-1-piperazinebutyramide]m aleate, AJ… (More)
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1993
1993
Preventive effect of a new calcium antagonist, monatepil, on drug-induced ischaemic electrocardiographic changes in rats.
1. The preventive effects of monatepil, a new calcium antagonist with alpha 1-adrenoceptor blocking activity, on ischaemic… (More)
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1993
1993
Anti-arrhythmic effects of a new calcium antagonist, monatepil, AJ-2615, in experimental arrhythmic models [corrected].
1. To characterize the anti-arrhythmic properties of a new calcium antagonist, monatepil [corrected], AJ-2615, the preventive… (More)
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