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monatepil

Known as: 11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleate, (+/-)-N-(6,11-Dihydrodibenzo(B,E)Thiepin-11-yl)-4-(P-Fluorophenyl)-1-Piperazinebutyramide, 1-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,e)thiepin-11-yl)-4-(4-fluorophenyl)-, (Z)-2-butenedioate (1:1) 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

AJ 2615monatepil maleate

Broader (5)

Adrenergic alpha-AntagonistsAntihypertensive AgentsCalcium Channel BlockersDibenzothiepins

Papers overview

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2017
2017
Effect of monatepil, a calcium channel blocker in ocular hypertensive rabbits
2013
2013
Synthesis and characterization
http://www.revistadechimie.ro 529 Dibenzothiepines are well-known especially for their antidepressant activity (e.g. Dosulepin… 
1997
1997
Effects of Monatepil, a Novel Calcium Antagonist with α1-Adrenergic Blocking Activity, on the Low-Density Lipoprotein Receptor in Human Skin Fibroblasts
To investigate the mechanisms of the hypolipidemic effect ofmonatepil, a new class of calcium antagonists withα1-adrenergic… 
1995
1995
Relative Contribution of α1-Adrenoceptor Blocking Activity to the Hypotensive Effect of the Novel Calcium Antagonist Monatepil
Summary: Monatepil, a novel calcium antagonist, has α1-adrenoceptor blocking activity; in the present study, we examined the… 
Review
1995
Review
1995
Newer antihypertensive drugs.
We review three new classes of antihypertensive drugs: imidazolines, monatepil, and neutral endopeptidase inhibitors… 
1994
1994
The efficacy of monatepil, a new calcium antagonist, in the treatment of essential hypertension.
A multicenter, open-label trial in Japan examined the efficacy, safety, and optimal dose of monatepil (AJ-2615) as monotherapy… 
1994
1994
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats.
Antianginal effects of monatepil ([(+-)-N-(6,11-dihydrodibenzo[b,e]thiepin-11-yl)-4-(4-fluor ophenyl)-1-piperazinebutanamide… 
Review
1994
Review
1994
New therapeutic trends in calcium antagonism. Are they meaningful?
Recent advances in the field of calcium antagonism include the development of long-acting calcium antagonists, some of which have… 
1993
1993
PREVENTIVE EFFECT OF A NEW CALCIUM ANTAGONIST, MONATEPIL, ON DRUG‐INDUCED ISCHAEMIC ELECTROCARDIOGRAPHIC CHANGES IN RATS
1. The preventive effects of monatepil, a new calcium antagonist with α1‐adrenoceptor blocking activity, on ischaemic… 
1993
1993
Anti-arrhythmic effects of a new calcium antagonist, monatepil, AJ-2615, in experimental arrhythmic models [corrected].
1. To characterize the anti-arrhythmic properties of a new calcium antagonist, monatepil [corrected], AJ-2615, the preventive… 
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