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monatepil

Known as: 11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleate, (+/-)-N-(6,11-Dihydrodibenzo(B,E)Thiepin-11-yl)-4-(P-Fluorophenyl)-1-Piperazinebutyramide, 1-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,e)thiepin-11-yl)-4-(4-fluorophenyl)-, (Z)-2-butenedioate (1:1) 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (2)

AJ 2615monatepil maleate

Broader (5)

Adrenergic alpha-AntagonistsAntihypertensive AgentsCalcium Channel BlockersDibenzothiepins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
New classes of antihypertensive drugs: therapeutic potentials.
A number of new classes of antihypertensive drugs have become available in the recent years which appear to hold therapeutic… 
Review
1996
Review
1996
Identifiable Achatina giant neurones: their localizations in ganglia, axonal pathways and pharmacological features.
1995
1995
Relative Contribution of α1-Adrenoceptor Blocking Activity to the Hypotensive Effect of the Novel Calcium Antagonist Monatepil
Summary: Monatepil, a novel calcium antagonist, has α1-adrenoceptor blocking activity; in the present study, we examined the… 
1994
1994
Comparative effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic-blocking activity, and nitrendipine on lipoprotein and carbohydrate metabolism in patients with hypertension.
The effects of monatepil, a new calcium antagonist with alpha 1-blocking activity, and nitrendipine on lipoprotein and… 
1994
1994
Noninvasive quantitative evaluation of early atherosclerosis and the effect of monatepil, a new antihypertensive agent. An interim report.
In two studies on the same group of patients we evaluated noninvasive methods of assessing atherosclerosis and determined the… 
1994
1994
Up-regulation of hepatic LDL receptor gene expression by monatepil, a novel calcium antagonist, in high cholesterol diet-fed Japanese monkeys.
The action of the novel antihypertensive calcium antagonist monatepil on the hepatic LDL receptor was investigated at the gene… 
Review
1994
Review
1994
Antihypertensive, antiatherosclerotic, and plasma lipid-lowering effects of monatepil, a novel calcium antagonist with alpha 1-adrenoceptor-blocking activity in experimental animals.
  • M. Miyazaki
  • American Journal of Hypertension
  • 1994
  • Corpus ID: 25899861
Traditional antihypertensive therapy has been shown to reduce the incidence of hypertension-related vascular injuries; however… 
1994
1994
Anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed Japanese Macaca fuscata…
1. The preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-N-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4… 
1993
1993
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
Effects of monatepil ([(+/-)-N-(6,11-dihydrodibenzo[b, e]thiepin-11-yl)-4-(p-fluorophenyl)-1-piperazinebutyramide]m aleate, AJ… 
1993
1993
PREVENTIVE EFFECT OF A NEW CALCIUM ANTAGONIST, MONATEPIL, ON DRUG‐INDUCED ISCHAEMIC ELECTROCARDIOGRAPHIC CHANGES IN RATS
1. The preventive effects of monatepil, a new calcium antagonist with α1‐adrenoceptor blocking activity, on ischaemic… 
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