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monatepil
Known as:
11-((4-(4-(4-fluorophenyl)-1-piperazinyl)butyryl)amino)-6,11-dihydrodibenzo(b,e)thiepin maleate
, (+/-)-N-(6,11-Dihydrodibenzo(B,E)Thiepin-11-yl)-4-(P-Fluorophenyl)-1-Piperazinebutyramide
, 1-Piperazinebutanamide, N-(6,11-dihydrodibenzo(b,e)thiepin-11-yl)-4-(4-fluorophenyl)-, (Z)-2-butenedioate (1:1)
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National Institutes of Health
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Related topics
Related topics
7 relations
Narrower (2)
AJ 2615
monatepil maleate
Broader (5)
Adrenergic alpha-Antagonists
Antihypertensive Agents
Calcium Channel Blockers
Dibenzothiepins
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
New classes of antihypertensive drugs: therapeutic potentials.
N. K. Singh
,
R. Goyal
Clinical and experimental hypertension
1999
Corpus ID: 20191208
A number of new classes of antihypertensive drugs have become available in the recent years which appear to hold therapeutic…
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Review
1996
Review
1996
Identifiable Achatina giant neurones: their localizations in ganglia, axonal pathways and pharmacological features.
H. Takeuchi
,
Y. Araki
,
+4 authors
S. Wong
General Pharmacology
1996
Corpus ID: 31624838
1995
1995
Relative Contribution of α1-Adrenoceptor Blocking Activity to the Hypotensive Effect of the Novel Calcium Antagonist Monatepil
T. Sugimoto
,
K. Hosoki
,
T. Karasawa
Journal of Cardiovascular Pharmacology
1995
Corpus ID: 1548014
Summary: Monatepil, a novel calcium antagonist, has α1-adrenoceptor blocking activity; in the present study, we examined the…
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1994
1994
Comparative effects of monatepil, a novel calcium antagonist with alpha 1-adrenergic-blocking activity, and nitrendipine on lipoprotein and carbohydrate metabolism in patients with hypertension.
J. Sasaki
,
T. Ogihara
,
+7 authors
K. Arakawa
American Journal of Hypertension
1994
Corpus ID: 27295126
The effects of monatepil, a new calcium antagonist with alpha 1-blocking activity, and nitrendipine on lipoprotein and…
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1994
1994
Noninvasive quantitative evaluation of early atherosclerosis and the effect of monatepil, a new antihypertensive agent. An interim report.
M. Tsushima
,
H. Koh
,
+5 authors
T. Omae
American Journal of Hypertension
1994
Corpus ID: 39462593
In two studies on the same group of patients we evaluated noninvasive methods of assessing atherosclerosis and determined the…
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1994
1994
Up-regulation of hepatic LDL receptor gene expression by monatepil, a novel calcium antagonist, in high cholesterol diet-fed Japanese monkeys.
M. Notake
,
Y. Kondo
,
H. Nomura
,
K. Nakano
,
K. Hosoki
,
M. Miyazaki
American Journal of Hypertension
1994
Corpus ID: 31873895
The action of the novel antihypertensive calcium antagonist monatepil on the hepatic LDL receptor was investigated at the gene…
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Review
1994
Review
1994
Antihypertensive, antiatherosclerotic, and plasma lipid-lowering effects of monatepil, a novel calcium antagonist with alpha 1-adrenoceptor-blocking activity in experimental animals.
M. Miyazaki
American Journal of Hypertension
1994
Corpus ID: 25899861
Traditional antihypertensive therapy has been shown to reduce the incidence of hypertension-related vascular injuries; however…
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1994
1994
Anti-atherosclerotic and plasma lipid lowering effects of the novel calcium blocker with alpha 1-adrenoceptor antagonistic activity, monatepil, in high cholesterol diet-fed Japanese Macaca fuscata…
M. Miyazaki
,
K. Hosoki
,
H. Okunishi
,
K. Ishii
,
A. Ikeno
,
Y. Okazaki
Arzneimittel-Forschung
1994
Corpus ID: 35604141
1. The preventive effects of atherosclerosis and hyperlipidemia of monatepil ([(+-)-N-(6,11-dihydrodibenzo [b,e]thiepin-11-yl)-4…
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1993
1993
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
I. Nose
,
T. Kataoka
,
+7 authors
T. Karasawa
Arzneimittel-Forschung
1993
Corpus ID: 25413441
Effects of monatepil ([(+/-)-N-(6,11-dihydrodibenzo[b, e]thiepin-11-yl)-4-(p-fluorophenyl)-1-piperazinebutyramide]m aleate, AJ…
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1993
1993
PREVENTIVE EFFECT OF A NEW CALCIUM ANTAGONIST, MONATEPIL, ON DRUG‐INDUCED ISCHAEMIC ELECTROCARDIOGRAPHIC CHANGES IN RATS
T. Yamamoto
,
K. Nakatsuji
,
K. Hosoki
,
T. Karasawa
Clinical and Experimental Pharmacology and…
1993
Corpus ID: 24136496
1. The preventive effects of monatepil, a new calcium antagonist with α1‐adrenoceptor blocking activity, on ischaemic…
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