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AGM 1470

Known as: AGM-1470 
 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Solid tumors depend on angiogenesis for their growth. In a transgenic mouse model of pancreatic islet cell carcinogenesis (RIP1… Expand
Highly Cited
1997
Highly Cited
1997
BACKGROUND Angiogenesis, the formation of new blood vessels, is essential for tumor growth. The inhibition of angiogenesis is… Expand
Highly Cited
1997
Highly Cited
1997
Angiogenesis, the growth of new blood vessels, occurs normally in female reproductive organs. We tested the hypothesis that… Expand
Highly Cited
1995
Highly Cited
1995
BACKGROUND In previous animal studies, interleukin 12 (IL 12) was shown to inhibit the growth of a wide spectrum of tumors in… Expand
Highly Cited
1994
Highly Cited
1994
Recently, we reported the anti-angiogenic action along with anti-tumour activity of TNP-470 (AGM-1470). In this study, the effect… Expand
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Highly Cited
1994
Highly Cited
1994
AGM-1470 is a potent angiogenesis inhibitor that is very effective in inhibiting endothelial cell proliferation in both in vitro… Expand
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Highly Cited
1994
Highly Cited
1994
Fumagillin analogue AGM-1470 potently inhibits angiogenesis with a minimal toxicity in vivo and is expected to be of therapeutic… Expand
Highly Cited
1993
Highly Cited
1993
The effect of the potent angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470), a semisynthetic analogue of… Expand
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Highly Cited
1993
Highly Cited
1993
The angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470) showed antitumor activity in three human cancer… Expand
Highly Cited
1991
Highly Cited
1991
The anti-angiogenic activity of AGM-1470, a new synthetic analog of fumagillin isolated from Aspergillus fumigatus, was… Expand