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TNP 470
Known as:
TNP-470
, TNP470
A synthetic analog of fumagillin, an antibiotic isolated from the fungus Aspergillus fumigatus fresenius with antineoplastic activity. TNP-470 binds…
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National Institutes of Health
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Related topics
Related topics
3 relations
AGM 1470
Broader (2)
Angiogenesis Inhibitors
O-(chloroacetylcarbamoyl)fumagillol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Inhibitory effects of TNP-470 in combination with BCNU on tumor growth of human glioblastoma xenografts
Dongxiao Yao 姚东晓
,
Hong-yang Zhao 赵洪洋
,
Fangcheng Zhang 张方成
,
Jian Chen 陈 剑
,
Xiaobing Jiang 姜晓兵
,
Xianli Zhu 朱贤立
Journal of Huazhong University of Science and…
2010
Corpus ID: 23915971
This study investigated the effect of TNP-470 in combination with carmustine (BCNU) on the growth of subcutaneously implanted…
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2006
2006
Efficacy of the fumagillin analog TNP-470 for Nucleospora salmonis and Loma salmonae infections in chinook salmon
tsha wytscha
2006
Corpus ID: 27635392
Oral treatment with fumagillin is effective for controlling various inicrosporean and myxosporean infections in fish. We tested a…
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2001
2001
Inhibitory effects of angiogenesis inhibitor TNP-470 on growth of a human malignant glioma cell line SHG-44 and its xenografted tumor
D. Lin
2001
Corpus ID: 87085005
Objective To investigate the effects of TNP 470 on the growth of a human malignant glioma cell line SHG 44 in vivo and in vitro…
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2000
2000
Effects of PTK 787 / ZK 222584 , a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases , on Primary Tumor , Metastasis , Vessel Density , and Blood Flow in a Murine…
J. Drevs
,
Inga Hofmann
,
+7 authors
D. Marmé
2000
Corpus ID: 22936311
Antiangiogenic therapy is a promising new strategy to inhibit tumor growth and formation of metastases. Vascular endothelial…
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1999
1999
Experimental study of the effect of angiogenesis inhibitor TNP-470 on the growth and metastasis of gastric cancer in vivo
Bing-ya Liu
,
Yan-zhen Lin
,
H. Yin
,
Rui-nian Wang
,
Zheng‐gang Zhu
,
Q. Gu
Zhonghua zhong liu za zhi [Chinese journal of…
1999
Corpus ID: 10603803
Objective: To study the effect of angiogenesis inhibitor TNP-470 on the growth and metastasis of gastric cancer in vivo. Methods…
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1999
1999
TNP-470 antiangiogenic therapy for advanced murine neuroblastoma
長渕 英介
1999
Corpus ID: 87585499
1997
1997
Discovery of TNP-470 and Other Angiogenesis Inhibitors
D. Ingber
1997
Corpus ID: 81304098
Most types of cancer chemotherapy, either currently available or in development, are cytotoxic in that they are designed to kill…
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1996
1996
The Fumagillin Analogue TNP-470 Inhibits DNA Synthesis of Vascular Smooth Muscle Cells Stimulated by Platelet-Derived Growth Factor and Insulin-like Growth Factor-I
HidenoriKoyama
,
YoshikiNishizawa
,
+4 authors
HirotoshiMorii
1996
Corpus ID: 91371310
The effect of an angiogenesis inhibitor, TNP-470, on DNA synthesis and its underlying signaling cascades stimulated by platelet…
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1996
1996
Antitumor effect of the angiogenesis inhibitor TNP-470 and its combination effect with 5-FU and PSK in colon 26 tumors.
M. Kitamura
,
K. Arai
,
Y. Iwasaki
,
M. Toi
Oncology Report
1996
Corpus ID: 7201091
TNP-470 is known to inhibit angiogenesis. In this study, we investigated the antitumor effect of TNP-470 in colon 26 tumors. A…
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1995
1995
Effects of tnp-470 (agm-1470) on tumor-growth, angiogenesis and serum copper levels in liver-cancer bearing rats.
S. Matsuoka
,
J. Uchino
,
Y. Une
,
H. Ishimura
,
S. Tsuchimoto
,
T. Kamiyama
Oncology Report
1995
Corpus ID: 21088767
Administration of TNP-470 (AGM-1470), a newly developed angiogenesis inhibitor, elevated serum copper concentrations (SCu) in a…
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