Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,197,876 papers from all fields of science
Search
Sign In
Create Free Account
TNP 470
Known as:
TNP-470
, TNP470
A synthetic analog of fumagillin, an antibiotic isolated from the fungus Aspergillus fumigatus fresenius with antineoplastic activity. TNP-470 binds…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
3 relations
AGM 1470
Broader (2)
Angiogenesis Inhibitors
O-(chloroacetylcarbamoyl)fumagillol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Neovascularization in human atherosclerosis.
P. Moreno
,
K. Purushothaman
,
E. Zias
,
J. Sanz
,
V. Fuster
Current molecular medicine
2006
Corpus ID: 2396475
In the absence of disease, microvessels provide vessel wall nutrients to the tunica media, while the intima is fed by oxygen…
Expand
Highly Cited
2005
Highly Cited
2005
Angiogenesis Is Required for Successful Bone Induction During Distraction Osteogenesis
Tony D. Fang
,
A. Salim
,
+8 authors
M. Longaker
Journal of Bone and Mineral Research
2005
Corpus ID: 26005717
The role of angiogenesis during mechanically induced bone formation is incompletely understood. The relationship between the…
Expand
Highly Cited
2004
Highly Cited
2004
Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice
E. Brakenhielm
,
R. Cao
,
+4 authors
Yihai Cao
Circulation Research
2004
Corpus ID: 12782696
Adipose tissue growth has been proposed to involve recruitment of new blood vessels. Here, we test the hypothesis that delivery…
Expand
Highly Cited
2004
Highly Cited
2004
Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
R. Satchi‐Fainaro
,
M. Puder
,
+5 authors
J. Folkman
Nature Network Boston
2004
Corpus ID: 36546176
Angiogenesis is crucial for tumor growth. Angiogenesis inhibitors, such as O-(chloracetyl-carbamoyl) fumagillol (TNP-470), are…
Expand
Highly Cited
2004
Highly Cited
2004
Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.
Brian K Adams
,
E. Ferstl
,
+10 authors
M. Shoji
Bioorganic & Medicinal Chemistry
2004
Corpus ID: 23451083
Review
2001
Review
2001
Angiogenesis: regulators and clinical applications.
S. Liekens
,
E. De Clercq
,
J. Neyts
Biochemical Pharmacology
2001
Corpus ID: 2290649
Highly Cited
2001
Highly Cited
2001
Prevention of fracture healing in rats by an inhibitor of angiogenesis.
M. Hausman
,
M. Schaffler
,
R. Majeska
Bone
2001
Corpus ID: 7317767
Highly Cited
2000
Highly Cited
2000
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.
T. Browder
,
C. Butterfield
,
+4 authors
J. Folkman
Cancer Research
2000
Corpus ID: 9224199
To reveal the antiangiogenic capability of cancer chemotherapy, we developed an alternative antiangiogenic schedule for…
Expand
Highly Cited
1999
Highly Cited
1999
Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.
K. Moulton
,
E. Heller
,
M. Konerding
,
E. Flynn
,
W. Palinski
,
J. Folkman
Circulation
1999
Corpus ID: 25315051
BACKGROUND Neovascularization within the intima of human atherosclerotic lesions is well described, but its role in the…
Expand
Highly Cited
1999
Highly Cited
1999
Tumor development under angiogenic signaling: a dynamical theory of tumor growth, treatment response, and postvascular dormancy.
P. Hahnfeldt
,
D. Panigrahy
,
J. Folkman
,
L. Hlatky
Cancer Research
1999
Corpus ID: 1109274
The effects of the angiogenic inhibitors endostatin, angiostatin, and TNP-470 on tumor growth dynamics are experimentally and…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE