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ADORA2A wt Allele

Known as: hA2aR, Adenosine A2 Receptor Gene, A2aR 
Human ADORA2A wild-type allele is located in the vicinity of 22q11.23 and is approximately 15 kb in length. This allele, which encodes adenosine A2a… 
National Institutes of Health

Related topics

Related topics

11 relations
22q11.23ADORA2A protein, humanADORA2B geneADORA2B protein, human

Broader (1)

ADORA2A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Diversity and bias through dopamine D2R heteroreceptor complexes
2012
2012
Decoupling of sleepiness from sleep time and intensity during chronic sleep restriction: evidence for a role of the adenosine system.
STUDY OBJECTIVE Sleep responses to chronic sleep restriction (CSR) might be very different from those observed after short-term… 
Highly Cited
2012
Highly Cited
2012
Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A1, A2A, A2B, and A3 receptor antagonists
FLAP fingerprints are applied in the ligand-, structure- and pharmacophore-based mode in a case study on antagonists of all four… 
Highly Cited
2008
Highly Cited
2008
Critical Role of Hypoxia and A2A Adenosine Receptors in Liver Tissue-Protecting Physiological Anti-Inflammatory Pathway
Whole body exposure of wild type control littermates and A2A adenosine receptor (A2AR) gene deleted mice to low oxygen containing… 
2008
2008
Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors
Abstract G protein-coupled receptors (GPCRs) represent the largest class of cell surface receptors and play crucial roles in many… 
2006
2006
Expression and functional purification of a glycosylation deficient version of the human adenosine 2a receptor for structural studies.
2004
2004
Input-Specific Modulation of Neurotransmitter Release in the Lateral Horn of the Spinal Cord via Adenosine Receptors
Activation of adenosine A2A receptors (A2ARs) in the CNS produces a variety of neuromodulatory actions dependent on the region… 
2003
2003
Adenosine A2A Receptor Gene Disruption Provokes Marked Changes in Melanocortin Content and Pro‐Opiomelanocortin Gene Expression
A2A receptor knockout (A2AR−/−) mice are more anxious and aggressive, and exhibit reduced exploratory activity than their wild… 
2003
2003
Relationships between cell division, expression of growth factors and microcirculation in the thyroids of Tg-A2aR transgenic mice and patients with Graves' disease.
Tissue heterogeneity and nodule formation are hallmarks of thyroid growth. This is accounted for by the clonality theory that… 
Highly Cited
2001
Highly Cited
2001
Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum
Adenosine A2A receptors (A2AR) and dopamine D2 receptors (D2R) are highly concentrated in the striatum, where they are co… 
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