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AD-6 (8-chlorocarbochromen)

Known as: AD 6, AD(6), AD6 
 
National Institutes of Health

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Broader (1)

cloricromen

Papers overview

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2014
2014
Amplified and Persistent Immune Responses Generated by Single-Cycle Replicating Adenovirus Vaccines
ABSTRACT Replication-competent adenoviral (RC-Ad) vectors generate exceptionally strong gene-based vaccine responses by… Expand
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Highly Cited
2011
Highly Cited
2011
Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer.
  • R. Khare, S. May, +6 authors M. Barry
  • Molecular therapy : the journal of the American…
  • 2011
    • Corpus ID: 29841501
As much as 90% of an intravenously (i.v.) injected dose of adenovirus serotype 5 (Ad5) is absorbed and destroyed by liver Kupffer… Expand
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2010
2010
Infection and killing of multiple myeloma by adenoviruses.
Oncolytic virotherapy makes use of the natural ability of viruses to infect and kill cancer cells. Adenovirus serotype 5 (Ad5… Expand
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2009
2009
Safety and Immunogenicity of the Merck Adenovirus Serotype 5 (MRKAd5) and MRKAd6 Human Immunodeficiency Virus Type 1 Trigene Vaccines Alone and in Combination in Healthy Adults
ABSTRACT Preexisting immunity to adenovirus serotype 5 (Ad5) diminishes immune responses to vaccines using Ad5 as a vector… Expand
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2000
2000
Efficacy of topical cidofovir on multiple adenoviral serotypes in the New Zealand rabbit ocular model.
PURPOSE The goal of the present study was to determine the efficacy of topical 0.5% cidofovir twice daily for 7 days on the… Expand
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1979
1979
The directionality of locomotion of mouse fibroblasts. Role of cell adhesiveness.
Abstract To evaluate the role of adhesiveness in cell locomotion we have compared the parameters of motion (rate and… Expand
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Highly Cited
1978
Highly Cited
1978
Decreased binding of epidermal growth factor to BALB/c 3T3 mutant cells defective in glycoprotein synthesis
THE surface of animal cells contains a variety of complex macromolecules, some of which modulate cell growth, adhesion and… Expand
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Highly Cited
1977
Highly Cited
1977
Microfilament bundles and cell shape are related to adhesiveness to substratum and are dissociable from growth control in cultured fibroblasts
The distribution of microfilament bundles in cells was examined using antibodies to fibroblast myosin and indirect… Expand
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Highly Cited
1977
Highly Cited
1977
Role of cell surface carbohydrates and proteins in cell behavior: studies on the biochemical reversion of an N-acetylglucosamine-deficient fibroblast mutant.
AD6, a mutant derived from 3T3 Balb/c cells, is characterized by low adhesion to substratum, round shape, increase in surface… Expand
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Highly Cited
1977
Highly Cited
1977
Mutants of mouse fibroblasts altered in the synthesis of cell surface glycoproteins. Preliminary evidence for a defect in the acetylation of glucosamine 6-phosphate.
We hve reported the isolation and preliminary biochemical characterization of two mutants of mouse fibroblasts selected for a… Expand
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