ACVRL1 wt Allele

Known as: ACVRL1, ALK-1, Activin A Receptor, Type II-Like Kinase 1 wt Allele 
Human ACVRL1 wild-type allele is located within 12q11-q14 and is approximately 14 kb in length. This allele, which encodes serine/threonine-protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Purpose: Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder characterized by arteriovenous malformations… (More)
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Highly Cited
2006
Highly Cited
2006
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterised by vascular malformations in… (More)
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Highly Cited
2005
Highly Cited
2005
Patients with hereditary haemorrhagic telangiectasia (HHT, or Osler-Weber-Rendu syndrome) have variable presentation patterns and… (More)
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Review
2005
Review
2005
Genetic studies in mice and humans have revealed the pivotal role of transforming growth factor-beta (TGF-beta) signaling during… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Mutations of the transforming growth factor beta (TGFbeta) receptor components ENDOGLIN and ALK-1 cause the autosomal… (More)
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Highly Cited
2002
Highly Cited
2002
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… (More)
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Highly Cited
2000
Highly Cited
2000
Hereditary Hemorrhagic Telangiectasia (HHT) is easily recognized in individuals displaying the classical triad of epistaxis… (More)
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Highly Cited
1999
Highly Cited
1999
The biological effects of type I serine/threonine kinase receptors and Smad proteins were examined using an adenovirus-based… (More)
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Highly Cited
1998
Highly Cited
1998
Transforming growth factor beta (TGF-beta) is an extracellular ligand that binds to a heterodimeric receptor, initiating signals… (More)
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Highly Cited
1996
Highly Cited
1996
Hereditary haemorrhagic telangiectasia, or Osler–Rendu–Weber (ORW) syndrome, is an autosomal dominant vascular dysplasia. So far… (More)
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