Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ACVRL1 wt Allele

Known as: ACVRL1, ALK-1, Activin A Receptor, Type II-Like Kinase 1 wt Allele 
Human ACVRL1 wild-type allele is located within 12q11-q14 and is approximately 14 kb in length. This allele, which encodes serine/threonine-protein… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterised by vascular malformations in… Expand
Is this relevant?
Review
2005
Review
2005
Genetic studies in mice and humans have revealed the pivotal role of transforming growth factor-beta (TGF-beta) signaling during… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Patients with hereditary haemorrhagic telangiectasia (HHT, or Osler-Weber-Rendu syndrome) have variable presentation patterns and… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Background: Mutations of the transforming growth factor β (TGFβ) receptor components ENDOGLIN and ALK-1 cause the autosomal… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Hereditary Hemorrhagic Telangiectasia (HHT) is easily recognized in individuals displaying the classical triad of epistaxis… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The biological effects of type I serine/threonine kinase receptors and Smad proteins were examined using an adenovirus-based… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Transforming growth factor beta (TGF-beta) is an extracellular ligand that binds to a heterodimeric receptor, initiating signals… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Hereditary haemorrhagic telangiectasia, or Osler–Rendu–Weber (ORW) syndrome, is an autosomal dominant vascular dysplasia. So far… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Human cDNA clones encoding four novel putative transmembrane protein serine/threonine kinases, denoted activin receptor-like… Expand
Is this relevant?