ACVRL1 gene

Known as: ACVRL1, ACTIVIN RECEPTOR-LIKE KINASE 1, Activin A Receptor, Type II-Like Kinase 1 Gene 
This gene is involved in the mediation of cell-surface receptor interactions for the TGF-beta superfamily of ligands.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2018
0204019712018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Arteriovenous malformations (AVMs) are fragile direct connections between arteries and veins that arise during times of active… (More)
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Highly Cited
2008
Highly Cited
2008
ALK1 belongs to the type I receptor family for transforming growth factor-beta family ligands. Heterozygous ALK1 mutations cause… (More)
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Highly Cited
2005
Highly Cited
2005
Patients with hereditary haemorrhagic telangiectasia (HHT, or Osler-Weber-Rendu syndrome) have variable presentation patterns and… (More)
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Highly Cited
2004
Highly Cited
2004
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder in humans that is characterised by multisystemic… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Mutations of the transforming growth factor beta (TGFbeta) receptor components ENDOGLIN and ALK-1 cause the autosomal… (More)
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Highly Cited
2003
Highly Cited
2003
Several characteristic morphological and functional differences distinguish arteries from veins. It was thought that hemodynamic… (More)
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Highly Cited
2002
Highly Cited
2002
Transforming growth factor-beta (TGF-beta) plays a crucial role in vascular development and homeostasis by regulating many… (More)
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Highly Cited
2000
Highly Cited
2000
Hereditary Hemorrhagic Telangiectasia (HHT) is easily recognized in individuals displaying the classical triad of epistaxis… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND There is an increasingly recognized association between pulmonary arteriovenous malformations (PAVM) and cerebral… (More)
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Highly Cited
1997
Highly Cited
1997
The activin receptor-like kinase 1 gene (ALK-1) is the second locus for the autosomal dominant vascular disease hereditary… (More)
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