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ACVR2B gene

Known as: ACTIVIN A RECEPTOR, TYPE IIB, Activin A Receptor, Type IIB Gene, ACVR2B 
This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Activin was discovered in the 1980s as a gonadal protein that stimulated FSH release from pituitary gonadotropes and was thought… 
Highly Cited
2003
Highly Cited
2003
The TGF‐β superfamily of ligands and receptors stimulate cellular events in diverse processes ranging from cell fate… 
Highly Cited
2002
Highly Cited
2002
Background: Two TGFβ‐related proteins, Nodal and Lefty, are implicated in early embryonic patterning of vertebrates. Genetic data… 
Highly Cited
2001
Highly Cited
2001
Nodal proteins have crucial roles in mesendoderm formation and left-right patterning during vertebrate development. The molecular… 
Highly Cited
2000
Highly Cited
2000
Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways… 
Highly Cited
1999
Highly Cited
1999
Endoglin (CD105) is a transmembrane glycoprotein that binds transforming growth factor (TGF)-β1 and -β3, and coprecipitates with… 
Highly Cited
1997
Highly Cited
1997
Vertebrate animals exhibit segmented axial skeletons and lateral asymmetry of the visceral organs. The segment identity of… 
Highly Cited
1995
Highly Cited
1995
Proteins in the TGF-beta superfamily transduce their effects through binding to type I and type II serine/threonine kinase… 
Highly Cited
1994
Highly Cited
1994
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a…