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ACVR2B gene

Known as: ACTIVIN A RECEPTOR, TYPE IIB, Activin A Receptor, Type IIB Gene, ACVR2B 
This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.
National Institutes of Health

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ACVR2B protein, humanACVR2B wt AlleleLigand BindingPattern Formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Advances in understanding and treating cardiac cachexia: highlights from the 5th Cachexia Conference.
2010
2010
Aberrantly increased mRNA expression of betaglycan, an inhibin co‐receptor in the ovarian tissues in women with polycystic ovary syndrome
Aim:  To compare the gene expressional levels of receptors for activins and inhibins in ovarian tissues between women with… 
2007
2007
Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans.
Genetic variation in myostatin, a negative regulator of skeletal muscle, in cattle has shown remarkable influence on skeletal… 
2006
2006
Inhibins are the major activin ligands expressed during early thymocyte development
Activins are members of the transforming growth factor‐beta (TGFβ) superfamily, which regulate cell differentiation processes… 
2002
2002
Gene‐dosage‐sensitive genetic interactions between inversus viscerum (iv), nodal, and activin type IIB receptor (ActRIIB) genes in asymmetrical patterning of the visceral organs along the left‐right…
We have shown previously that mice deficient in the activin type IIB receptor (ActRIIB) exhibit right isomerism, which is… 
Highly Cited
2000
Highly Cited
2000
Activin receptor patterning of foregut organogenesis.
Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways… 
2000
2000
Editorial: In Search of Binding-Identification of Inhibin Receptors.
The cloning of the inhibin subunit genes in the mid-1980s sparked a passionate search for the inhibin receptors and the roles… 
1999
1999
Cloning of zebrafish activin type IIB receptor (ActRIIB) cDNA and mRNA expression of ActRIIB in embryos and adult tissues
1998
1998
Activin Regulates βA-Subunit and Activin Receptor Messenger Ribonucleic Acid and Cellular Proliferation in Activin-Responsive Testicular Tumor Cells.
Activin, a member of the transforming growth factor-beta superfamily of growth and differentiation factors, has a number of… 
Highly Cited
1993
Highly Cited
1993
Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.
In addition to the feedback regulation of pituitary FSH secretion, gonadal activins have been shown to modulate physiological… 
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