Skip to search formSkip to main contentSkip to account menu

ACVR2B gene

Known as: ACTIVIN A RECEPTOR, TYPE IIB, Activin A Receptor, Type IIB Gene, ACVR2B 
This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.
National Institutes of Health

Related topics

Related topics

9 relations
ACVR2B protein, humanACVR2B wt AlleleLigand BindingPattern Formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
Background: Two TGFβ‐related proteins, Nodal and Lefty, are implicated in early embryonic patterning of vertebrates. Genetic data… 
Highly Cited
2002
Highly Cited
2002
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.
Vertebral bodies are segmented along the anteroposterior (AP) body axis, and the segmental identity of the vertebrae is… 
Highly Cited
2001
Highly Cited
2001
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.
Nodal proteins have crucial roles in mesendoderm formation and left-right patterning during vertebrate development. The molecular… 
Highly Cited
2000
Highly Cited
2000
Activin receptor patterning of foregut organogenesis.
Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways… 
Highly Cited
1999
Highly Cited
1999
The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice.
The type II activin receptors, ActRIIA and ActRIIB, have been shown to play critical roles in axial patterning and organ… 
Highly Cited
1997
Highly Cited
1997
The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse.
Vertebrate animals exhibit segmented axial skeletons and lateral asymmetry of the visceral organs. The segment identity of… 
Highly Cited
1994
Highly Cited
1994
Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis.
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a… 
Highly Cited
1994
Highly Cited
1994
Hybridization histochemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis.
We have studied the distribution of activin receptor gene expression in the brain, pituitary, ovary, and testis of the adult rat… 
Highly Cited
1993
Highly Cited
1993
Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.
In addition to the feedback regulation of pituitary FSH secretion, gonadal activins have been shown to modulate physiological… 
Highly Cited
1992
Highly Cited
1992
Cloning of a second type of activin receptor and functional characterization in Xenopus embryos.
A complementary DNA coding for a second type of activin receptor (ActRIIB) has been cloned from Xenopus laevis that fulfills the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)