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ACVR2B gene

Known as: ACTIVIN A RECEPTOR, TYPE IIB, Activin A Receptor, Type IIB Gene, ACVR2B 
This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Recent high-profile studies report conflicting data on the age-related change in circulating growth/differentiation factor 11… Expand
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Highly Cited
2012
Highly Cited
2012
Sarcopenia, the age-related loss of skeletal muscle, is characterized by a deterioration of muscle quantity and quality leading… Expand
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Highly Cited
2010
Highly Cited
2010
Muscle wasting and cachexia have long been postulated to be key determinants of cancer-related death, but there has been no… Expand
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Highly Cited
2010
Highly Cited
2010
Cachexia, progressive loss of fat and muscle mass despite adequate nutrition, is a devastating complication of cancer associated… Expand
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Highly Cited
2009
Highly Cited
2009
UNLABELLED Methodological problems, including binding of myostatin to plasma proteins and cross-reactivity of assay reagents with… Expand
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Highly Cited
2007
Highly Cited
2007
Recent data indicate that the Bone Morphogenetic Protein BMP-7 exhibits mucosal protection against experimental colitis in rats… Expand
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Highly Cited
2003
Highly Cited
2003
Myostatin, a transforming growth factor beta (TGF-beta) family member, is a potent negative regulator of skeletal muscle growth… Expand
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Highly Cited
2001
Highly Cited
2001
Sorting nexins (SNX) comprise a family of proteins with homology to several yeast proteins, including Vps5p and Mvp1p, that are… Expand
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Highly Cited
1999
Highly Cited
1999
Endoglin (CD105) is a transmembrane glycoprotein that binds transforming growth factor (TGF)-beta1 and -beta3, and coprecipitates… Expand
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Highly Cited
1994
Highly Cited
1994
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a… Expand
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