Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 209,921,007 papers from all fields of science
Search
Sign In
Create Free Account
ACVR2B gene
Known as:
ACTIVIN A RECEPTOR, TYPE IIB
, Activin A Receptor, Type IIB Gene
, ACVR2B
Expand
This gene plays a role in the transforming growth factor-beta signal transduction pathway and is essential for ligand binding and kinase activity.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
9 relations
ACVR2B protein, human
ACVR2B wt Allele
Ligand Binding
Pattern Formation
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
Xíaolan Zhou
,
Jin Wang
,
+10 authors
H. Q. Han
Cell
2010
Corpus ID: 3495800
Review
2009
Review
2009
The biology of activin: recent advances in structure, regulation and function.
Yin Xia
,
A. Schneyer
Journal of Endocrinology
2009
Corpus ID: 24652144
Activin was discovered in the 1980s as a gonadal protein that stimulated FSH release from pituitary gonadotropes and was thought…
Expand
Highly Cited
2003
Highly Cited
2003
Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF‐β ligand:receptor interactions
T. B. Thompson
,
T. Woodruff
,
T. Jardetzky
EMBO Journal
2003
Corpus ID: 23752350
The TGF‐β superfamily of ligands and receptors stimulate cellular events in diverse processes ranging from cell fate…
Expand
Highly Cited
2002
Highly Cited
2002
Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
R. Sakuma
,
Y. Ohnishi
,
+7 authors
H. Hamada
Genes to Cells
2002
Corpus ID: 19320756
Background: Two TGFβ‐related proteins, Nodal and Lefty, are implicated in early embryonic patterning of vertebrates. Genetic data…
Expand
Highly Cited
2001
Highly Cited
2001
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.
E. Reissmann
,
H. Jörnvall
,
+6 authors
A. Brivanlou
Genes & Development
2001
Corpus ID: 5107692
Nodal proteins have crucial roles in mesendoderm formation and left-right patterning during vertebrate development. The molecular…
Expand
Highly Cited
2000
Highly Cited
2000
Activin receptor patterning of foregut organogenesis.
S. K. Kim
,
M. Hebrok
,
+5 authors
D. Melton
Genes & Development
2000
Corpus ID: 25116671
Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways…
Expand
Highly Cited
1999
Highly Cited
1999
Endoglin Is an Accessory Protein That Interacts with the Signaling Receptor Complex of Multiple Members of the Transforming Growth Factor-β Superfamily*
Nadia Barbara
,
J. Wrana
,
M. Letarte
Journal of Biological Chemistry
1999
Corpus ID: 37266495
Endoglin (CD105) is a transmembrane glycoprotein that binds transforming growth factor (TGF)-β1 and -β3, and coprecipitates with…
Expand
Highly Cited
1997
Highly Cited
1997
The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse.
S. P. Oh
,
E. Li
Genes & Development
1997
Corpus ID: 37031674
Vertebrate animals exhibit segmented axial skeletons and lateral asymmetry of the visceral organs. The segment identity of…
Expand
Highly Cited
1995
Highly Cited
1995
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects
H. Yamashita
,
P. ten Dijke
,
+5 authors
K. Miyazono
Journal of Cell Biology
1995
Corpus ID: 956870
Proteins in the TGF-beta superfamily transduce their effects through binding to type I and type II serine/threonine kinase…
Expand
Highly Cited
1994
Highly Cited
1994
Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis.
V. Roberts
,
S. Barth
Endocrinology
1994
Corpus ID: 2371203
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE