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ACVR2B wt Allele

Known as: ACVR2B, Activin A Receptor, Type IIB wt Allele 
Human ACVR2B wild-type allele is located within 3p22 and is approximately 29 kb in length. This allele, which encodes activin receptor type 2B… Expand
National Institutes of Health

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11 relations
3p22ACVR2B geneACVR2B protein, humanHomo sapiens
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Papers overview

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2020
2020
MicroRNA‑21 serves an important role during PAOO‑facilitated orthodontic tooth movement.
Periodontal accelerate osteogenesis orthodontics (PAOO) is an extension of described techniques that surgically alter the… Expand
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2019
2019
Modulation of connective tissue growth factor and activin receptor 2b function in cardiac hypertrophy and fibrosis
The increase of cardiac hemodynamic load that requires increased mechanical performance drives adaptation of the heart to… Expand
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2018
2018
Activin receptors regulate the oligodendrocyte lineage in health and disease
The most prevalent neurological disorders of myelin include perinatal brain injury leading to cerebral palsy in infants and… Expand
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2017
2017
Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass
Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks… Expand
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2016
2016
Downstream mRNA Target Analysis in Neonatal Hypoxic-Ischaemic Encephalopathy Identifies Novel Marker of Severe Injury: a Proof of Concept Paper
Human microRNA miR-374a is downregulated in the umbilical cord blood (UCB) of infants with hypoxic-ischaemic encephalopathy (HIE… Expand
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2015
2015
A Soluble Activin Receptor Type IIB Does Not Improve Blood Glucose in Streptozotocin-Treated Mice
Type 1 diabetes mellitus (T1DM), or insulin dependent DM, is accompanied by decreased muscle mass. The growth factor myostatin… Expand
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2015
2015
Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy
Myostatin is a secreted signaling molecule that normally acts to limit muscle growth. As a result, there is extensive effort… Expand
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2014
2014
Myostatin stimulates, not inihibits, C2C12 myoblast proliferation.
The immortal C2C12 cell line originates from dystrophic mouse thigh muscle and has been used to study the endocrine control of… Expand
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Highly Cited
1999
Highly Cited
1999
Left-right axis malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB.
Targeted disruption of the mouse activin receptor type IIB gene (Acvr2b) results in abnormal left-right (LR) axis development… Expand
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