ACTN4 gene

Known as: Actinin Alpha 4 Gene, ACTININ-4, ACTININ, ALPHA-4 
This gene plays a role in the binding of actin to other cellular structures.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2018
05101519792018

Papers overview

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2013
2013
Murine double minute (MDM2) binding protein (MTBP) has been implicated in cancer progression. Here, we demonstrate one mechanism… (More)
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2010
2010
The ubiquitously expressed family of alpha-actinins bridges actin filaments to stabilize adhesions, a process disrupted during… (More)
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2008
2008
BACKGROUND & AIMS Human hepatocellular carcinoma (HCC) can invade the portal vein and metastasize to other parts of the liver… (More)
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2008
2008
PURPOSE An invasive growth pattern is one of the hallmarks of pancreatic ductal carcinoma. Actinin-4 is an actin-binding protein… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Enhanced motility of cancer cells by remodeling of the actin cytoskeleton seems crucial in the process of… (More)
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2005
2005
BACKGROUND Congenital nephrotic syndrome (CNS) causes significant renal failure, and is classified into two types: (1) Finnish… (More)
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Highly Cited
2003
Highly Cited
2003
Dominantly inherited mutations in ACTN4, which encodes alpha-actinin-4, cause a form of human focal and segmental… (More)
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Highly Cited
2000
Highly Cited
2000
Focal and segmental glomerulosclerosis (FSGS) is a common, non-specific renal lesion. Although it is often secondary to other… (More)
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Highly Cited
2000
Highly Cited
2000
Focal and segmental glomerulosclerosis (FSGS) is a common, non-specific renal lesion. Although it is often secondary to other… (More)
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2000
2000
α-Actinins are actin-binding proteins important in organization of the cytoskeleton and in cell adhesion. We have cloned and… (More)
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