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ACTN4 gene

Known as: Actinin Alpha 4 Gene, ACTININ-4, ACTININ, ALPHA-4 
This gene plays a role in the binding of actin to other cellular structures.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Significance In this study, we examine how proteins that cross-link actin filaments control certain biophysical aspects of living… Expand
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2009
2009
The ubiquitously expressed family of α-actinins bridges actin filaments to stabilize adhesions, a process disrupted during growth… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Enhanced motility of cancer cells by remodeling of the actin cytoskeleton seems crucial in the process of… Expand
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Highly Cited
2003
Highly Cited
2003
Dominantly inherited mutations in ACTN4, which encodes alpha-actinin-4, cause a form of human focal and segmental… Expand
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Highly Cited
2000
Highly Cited
2000
Focal and segmental glomerulosclerosis (FSGS) is a common, non-specific renal lesion. Although it is often secondary to other… Expand
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Highly Cited
2000
Highly Cited
2000
Focal and segmental glomerulosclerosis (FSGS) is a common, non-specific renal lesion. Although it is often secondary to other… Expand
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Highly Cited
2000
Highly Cited
2000
ilies FS-A, FS-X and FS-CI. Individuals with end-stage renal disease are labelled ‘ESRD’. Urine protein measurements are shown… Expand
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Highly Cited
2000
Highly Cited
2000
We have applied fluorescence ratio imaging to the analysis of an actin-binding protein concentration relative to F-actin in… Expand
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Highly Cited
1998
Highly Cited
1998
Regulation of the actin cytoskeleton may play a crucial role in cell motility and cancer invasion. We have produced a monoclonal… Expand
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Highly Cited
1990
Highly Cited
1990
A number of cytoskeletal-associated pro- teins that are concentrated in focal contacts, namely ot-actinin, vinculin, talin, and… Expand
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