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ACTN4 gene

Known as: Actinin Alpha 4 Gene, ACTININ-4, ACTININ, ALPHA-4 
This gene plays a role in the binding of actin to other cellular structures.
National Institutes of Health

Related topics

Related topics

6 relations
ACTN4 protein, humanACTN4 wt AlleleCalcium BindingCytoskeletal Modeling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Identification of a Novel LXXLL Motif in α-Actinin 4-spliced Isoform That Is Critical for Its Interaction with Estrogen Receptor α and Co-activators*
Background: ACTN4 potentiates nuclear receptor (NR)-mediated transcriptional activity. Results: The flanking sequences to the… 
2012
2012
ACTN4 gene amplification and actinin‐4 protein overexpression drive tumour development and histological progression in a high‐grade subset of ovarian clear‐cell adenocarcinomas
Yamamoto S, Tsuda H, Honda K, Takano M, Tamai S, Imoto I, Inazawa J, Yamada T & Matsubara O 
(2012) Histopathology 60,1073–1083 
Review
2011
Review
2011
Molecular and Genetic Basis of Inherited Nephrotic Syndrome
Nephrotic syndrome is an heterogeneous disease characterized by increased permeability of the glomerular filtration barrier for… 
2009
2009
Differential LC-MS-based proteomics of surgical human cholangiocarcinoma tissues.
Cholangiocarcinoma is an intractable cancer for which there is no effective therapy other than surgical resection, and many… 
2007
2007
Direct binding of alpha-actinin enhances TRPP3 channel activity.
Transient receptor potential (TRP) polycystin 2 and 3 (TRPP2 and 3) are homologous members of the TRP superfamily of cation… 
Highly Cited
2005
Highly Cited
2005
E-cadherin regulates the association between beta-catenin and actinin-4.
The E-cadherin/catenin system acts as an invasion suppressor of epithelial malignancies. This invasion suppressive activity seems… 
2004
2004
Two distinct classes of CCAAT box elements that bind nuclear factor-Y/alpha-actinin-4: potential role in human CYP1A1 regulation.
Highly Cited
2002
Highly Cited
2002
Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution
We have previously identified an antigen (Ag) recognized on a human large cell carcinoma of the lung by a tumor-specific… 
Highly Cited
2001
Highly Cited
2001
Interactions of a hemidesmosome component and actinin family members.
Hemidesmosomes are multimeric protein complexes that attach epithelial cells to their underlying matrix and serve as cell surface… 
Highly Cited
1992
Highly Cited
1992
Association of Intercellular Adhesion Moleculeq (ICAM-1) with Actin-containing Cytoskeleton and -actinin
We have studied the cytoskeletal association of intercellular adhesion molecule-1 (ICAM-1, CD54), an integral membrane protein… 
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