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ACTN4 wt Allele

Known as: Actinin, Alpha-4 Gene, Focal Segmental Glomerulosclerosis 1 Gene, ACTININ-4 
Human ACTN4 wild-type allele is located in the vicinity of 19q13 and is approximately 84 kb in length. This allele, which encodes alpha-actinin-4… 
National Institutes of Health

Related topics

Related topics

7 relations
19q13ACTN4 geneCalcium BindingCytoskeletal Modeling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Actinin-4 Expression Predicts Poor Disease-free Survival and Correlates with Delayed Lymph Node Metastasis in Patients with Completely Resected Oral Squamous Cell Carcinoma.
Oral squamous cell carcinoma is generally characterized by poor prognosis, and biomarkers are needed for development and… 
2014
2014
Predictive Significance of Actinin-4 (ACTN4) Gene Expression in Early-Stage Non-Small Cell Lung Cancer (NSCLC)
2012
2012
ACTN4 gene amplification and actinin‐4 protein overexpression drive tumour development and histological progression in a high‐grade subset of ovarian clear‐cell adenocarcinomas
Yamamoto S, Tsuda H, Honda K, Takano M, Tamai S, Imoto I, Inazawa J, Yamada T & Matsubara O 
(2012) Histopathology 60,1073–1083 
2012
2012
Abstract 695: Significant loss of nuclear expression of Actinin-4 in metastatic breast carcinoma and lymph nodes: A novel biomarker for metastatic breast carcinoma
Background: Actinin-4 is an actin cross-linked protein. The expression and subcellular distribution of actinin-4 (ACTN4) has been… 
2009
2009
Actinin-4 Expression in Primary and Metastasized Pancreatic Ductal Adenocarcinoma
Objectives: Actinin-4 is an actin-bundling protein that probably has a tumor-promoting potential in several solid tumors. The… 
2009
2009
Dynamic Viscoelasticity of Actin Networks Cross-Linked with Wild-Type and Mutant a-Actinin-4 by
The actin cross-linker a-actinin-4 has been found indispensable for the structural and functional integrity of podocytes… 
2006
2006
Prednisone/cyclophosphamide treatment in adult-onset autosomal dominant familial focal segmental glomerulosclerosis (FSGS 1).
Familial FSGS is a heterogeneous disease characterized by proteinuria and an unremitting deterioration of the excretory function… 
Highly Cited
2005
Highly Cited
2005
E-cadherin regulates the association between beta-catenin and actinin-4.
The E-cadherin/catenin system acts as an invasion suppressor of epithelial malignancies. This invasion suppressive activity seems… 
2004
2004
Two distinct classes of CCAAT box elements that bind nuclear factor-Y/alpha-actinin-4: potential role in human CYP1A1 regulation.
2001
2001
rapid communication CD 2 AP and p 130 Cas localize to different F-actin structures in podocytes
Welsch, T., N. Endlich, W. Kriz, and K. Endlich. CD2AP and p130Cas localize to different F-actin structures in podocytes. Am J… 
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