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Fibric acid derivatives are used to treat hyperlipidemia and have wide ranging effects on lipid metabolism. The action of these… Expand Acyl-CoA:cholesterol acyltransferase (ACAT) catalyzes esterification of cellular cholesterol. To investigate the role of ACAT-1… Expand We examined the inhibitory potency of F-1394 ((1S,2S)-2-[3-(2,2-dimethylpropyl)-3-nonylureido]cyclohexane -1-yl 3-[(4R)-N-(2,2,5… Expand The hyperlipidemia- and atherosclerosis-prone (HAP) Japanese quail is a strain developed for the study of atherosclerosis by… Expand Oral administration of ursodeoxycholic acid (UDCA) renders bile unsaturated with cholesterol by reducing the hepatic output of… Expand CI-976, a new trimethoxy fatty acid anilide, is a potent and specific inhibitor of liver and intestinal acyl coenzyme A… Expand It has been supposed that prostacyclin (PGI2) and its analogues have important antiatherogenic effects. The aim of this work was… Expand 1. The acyl-CoA:cholesterol acyltransferase (ACAT) activity and lipid composition of intestinal microsomal membrane were… Expand The effects of 3 beta-blockers with different pharmacological properties (non-selective: propranolol; beta 1-selective… Expand Dietary administration (0.1% in a chow diet for 8 days) of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of… Expand