Skip to search formSkip to main contentSkip to account menu

ACAT activity

Known as: sterol O-acyltransferase activity, sterol-ester synthase activity, sterol-ester synthetase activity 
Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester. [EC:2.3.1.26, GOC:mah]
National Institutes of Health

Related topics

Related topics

3 relations
ACAT1 geneSOAT1 gene

Narrower (1)

cholesterol O-acyltransferase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Effects of dietary soybean lecithin on plasma lipid transport and hepatic cholesterol metabolism in rats.
1998
1998
Effects of F-1394, an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on ACAT activity in HepG2 cells and on hepatic secretion of lipids in Triton WR-1339-induced hyperlipidemic rats: possible…
We examined the inhibitory potency of F-1394 ((1S,2S)-2-[3-(2,2-dimethylpropyl)-3-nonylureido]cyclohexane -1-yl 3-[(4R)-N-(2,2,5… 
1996
1996
Effect of dietary cholesterol on the activities of key enzymes of cholesterol metabolism in hyperlipidemia- and atherosclerosis-prone Japanese quail.
The hyperlipidemia- and atherosclerosis-prone (HAP) Japanese quail is a strain developed for the study of atherosclerosis by… 
1996
1996
Activation of acyl-coenzyme A:cholesterol acyltransferase activity by cholesterol is not due to altered mRNA levels in HepG2 cells.
Review
1994
Review
1994
Effect of ursodeoxycholic acid on hepatic cholesterol metabolism.
Oral administration of ursodeoxycholic acid (UDCA) renders bile unsaturated with cholesterol by reducing the hepatic output of… 
1994
1994
The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat
Fibric acid derivatives are used to treat hyperlipidemia and have wide ranging effects on lipid metabolism. The action of these… 
1992
1992
Inhibition of ACAT activity after 7-oxo-PGI2 treatment in cholesterol-fed rabbits.
1990
1990
The antihypertensive drug propranolol enhances LDL catabolism and alters cholesterol metabolism in human cultured fibroblasts.
1990
1990
Effect of distal small bowel resection on ACAT activity and microsomal lipid composition in rat small intestine.
1987
1987
Inhibitors of sterol synthesis. Effect of dietary 5 alpha-cholest-8(14)-en-3 beta-ol-15-one on ACAT activity of jejunal microsomes of the rat.
Dietary administration (0.1% in a chow diet for 8 days) of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)