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cholesterol O-acyltransferase activity

Known as: acylcoenzyme A:cholesterol O-acyltransferase activity, acyl-CoA:cholesterol acyltransferase activity, cholesteryl ester synthetase activity 
Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA. [EC:2.3.1.26, RHEA:17732]
National Institutes of Health

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ACAT activity

Papers overview

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2004
2004
Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells.
Review
1996
Review
1996
Cholesterol efflux from macrophages and other cells
Foam cell formation by lipid accumulation in macrophages is a prominent finding in atherosclerotic plaques. Since macrophages… 
1989
1989
Effects of MK-733 (simvastatin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on intestinal acylcoenzyme A:cholesterol acyltransferase activity in rabbits.
Highly Cited
1987
Highly Cited
1987
Regulation of cholesterol esterification by micellar cholesterol in CaCo-2 cells.
The regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) activity by cholesterol was studied in an established… 
1987
1987
Solubilisation and reconstitution of acylcoenzyme A:estradiol-17 beta acyltransferase.
1984
1984
Regulation of acylcoenzyme A. Cholesterol acyltransferase and 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by lipoproteins in the intestine of parabiont rats.
Parabiont rats were used to study the regulation of intestinal cholesterol synthesis (3-hydroxy-3-methylglutaryl coenzyme A [HMG… 
1983
1983
Dietary Fat Saturation and Hepatic Acylcoenzyme A: Cholesterol Acyltransferase Activity Effect of n‐3 Polyunsaturated and Long‐Chain Saturated Fat
The acylcoenzyme A:cholesterol acyltransferase (ACAT) activity in liver microsomes from rats fed a diet containing 14% menhaden… 
1981
1981
Hepatic acylcoenzyme A: cholesterol acyltransferase activity during diet-induced hypercholesterolemia in cynomolgus monkeys.
Acylcoenzyme A: cholesterol acyltransferase (ACAT) activity was studied in hepatic microsomes of cynomolgus monkeys fed either… 
Highly Cited
1977
Highly Cited
1977
Effect of dietary fat saturation on acylcoenzyme A:-cholesterol acyltransferase activity of Ehrlich cell microsomes.
Ehrlich cells grown in mice fed coconut oil diets (highly saturated) contain about twice as much cholesteryl ester as those grown… 
1977
1977
Effect of prostaglandins E1 and F1alpha on the activities of cholesteryl ester synthetase and cholesteryl ester hydrolases of pigeon aorta in vitro.
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