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ABCB4 gene

Known as: ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Gene, GBD1, ATP-BINDING CASSETTE, SUBFAMILY B, MEMBER 4 
This gene is involved in the cellular export of organic anions and drugs and the intramembrane transport of phosphatidylcholine.
National Institutes of Health

Related topics

Related topics

9 relations
ABCB4 protein, humanDrug EffluxHomo sapiensLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Zebrafish Abcb4 is a potential efflux transporter of microcystin-LR.
2014
2014
External Validation of Scoring Instruments for Evaluating Pediatric Resuscitation
Introduction Although many methods have been proposed to assess clinical performance during resuscitation, robust and… 
2010
2010
The cholangiographic features of severe forms of ABCB4/MDR3 deficiency-associated cholangiopathy in adults.
2002
2002
Multidrug resistance 3 gene mutation 1712delT and estrogen receptor alpha gene polymorphisms in Finnish women with obstetric cholestasis.
Highly Cited
1999
Highly Cited
1999
Large Scale Purification of Detergent-soluble P-glycoprotein fromPichia pastoris Cells and Characterization of Nucleotide Binding Properties of Wild-type, Walker A, and Walker B Mutant Proteins*
P-glycoprotein (Pgp; mouse MDR3) was expressed inPichia pastoris, grown in fermentor culture, and purified. The final pure… 
1999
1999
Studies of Human MDR1-MDR2 Chimeras Demonstrate the Functional Exchangeability of a Major Transmembrane Segment of the Multidrug Transporter and Phosphatidylcholine Flippase
ABSTRACT P-glycoprotein (P-gp), encoded by the MDR1 gene, is a plasma membrane transporter which effluxes a large number of… 
Review
1995
Review
1995
The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology.
1995
1995
Characterization of the promoter region of the human MDR3 P-glycoprotein gene.
Highly Cited
1993
Highly Cited
1993
Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein
Monoclonal antibodies (MAbs) recognizing external epitopes of the human MDRI P‐glycoprotein have been used both for the detection… 
Highly Cited
1992
Highly Cited
1992
Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.
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