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ABCB4 protein, human

Known as: P-Glycoprotein 3, Multidrug Resistance Protein 3, Multiple Drug Resistance 3 
Multidrug resistance protein 3 (1286 aa, ~142 kDa) is encoded by the human ABCB4 gene. This protein is involved in the transport of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Drugs induce cholestasis by diverse and still poorly understood mechanisms in humans. Early hepatic effects of chlorpromazine… Expand
Highly Cited
2013
Highly Cited
2013
Bezafibrate is a widely used hypolipidemic agent and is known as a ligand of the peroxisome proliferator‐activated receptors… Expand
Highly Cited
2009
Highly Cited
2009
The phytoestrogen resveratrol has putative health-promoting effects and is present in several dietary constituents. Resveratrol… Expand
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Highly Cited
2007
Highly Cited
2007
Objectives Increasing evidence suggests that a genetically determined functional impairment of the hepatocellular efflux… Expand
Highly Cited
2004
Highly Cited
2004
Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder associated with increased risk of intrauterine fetal death and… Expand
Highly Cited
2004
Highly Cited
2004
The human multidrug resistance protein 3 (MRP3, symbol ABCC3) is an ATP-binding cassette transporter that mediates the efflux of… Expand
Highly Cited
2003
Highly Cited
2003
Many of the transporters involved in the transport of bile acids in the enterohepatic circulation have been characterized. The… Expand
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Highly Cited
2001
Highly Cited
2001
The enterohepatic circulation is essential for the maintenance of bile acids and cholesterol homeostasis. The ileal bile acid… Expand
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance-associated protein 1 (MRP1) and the canalicular multispecific organic anion transporter (cMOAT or MRP2… Expand
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance proteins MRP2 (symbol ABCC2) and MRP3 (symbol ABCC3) are conjugate export pumps expressed in hepatocytes… Expand