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A-740003

Known as: A740003 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy
Background/Aims: Previously, we demonstrated that blockade of the intracellular clearance systems in human retinal pigment… 
Highly Cited
2018
Highly Cited
2018
Serum amyloid A primes microglia for ATP-dependent interleukin-1β release
BackgroundAcute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute… 
2018
2018
1,4-Naphthoquinones potently inhibiting P2X7 receptor activity.
2018
2018
Mechanism of P2X7 receptor-dependent enhancement of neuromuscular transmission in pannexin 1 knockout mice
P2X7 receptors are present in presynaptic membranes of motor synapses, but their regulatory role in modulation of… 
Highly Cited
2017
Highly Cited
2017
The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain
Inflammatory responses play a key role in many neural pathologies, with localized signaling from the non-immune cells making… 
2017
2017
Potential role of P2X7R in esophageal squamous cell carcinoma proliferation
Esophageal cancer is an aggressive tumor and is the sixth leading cause of cancer death worldwide. ATP is well known to regulate… 
2015
2015
P2X7R activation drives distinct IL-1 responses in dendritic cells compared to macrophages
Highly Cited
2011
Highly Cited
2011
The P2X7 Receptor and Pannexin-1 Are Both Required for the Promotion of Multinucleated Macrophages by the Inflammatory Cytokine GM-CSF
The P2X7 receptor (P2X7R), an ATP-gated ion channel, has been implicated in the process of cell-to-cell fusion into… 
Review
2007
Review
2007
P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice.
Review
2007
Review
2007
Novel P2X7 receptor antagonists ease the pain
In recent months, a series of chemically diverse antagonists has been identified for the ATP‐gated P2X7 receptor. In particular… 
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