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8-oxoadenine

National Institutes of Health

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Broader (1)

8-hydroxyadenine

Papers overview

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2016
2016
MTH1 Substrate Recognition—An Example of Specific Promiscuity
MTH1 (NUDT1) is an oncologic target involved in the prevention of DNA damage. We investigate the way MTH1 recognises its… 
Review
2015
Review
2015
Diverse effects of naturally occurring base lesions on the structure and stability of the human telomere DNA quadruplex.
Highly Cited
2010
Highly Cited
2010
Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.
Systemic administration of a Toll-like receptor 7 (TLR7) agonist is effective to in suppressing Th2 derived inflammation, however… 
2003
2003
Site-specific DNA Transesterification by Vaccinia Topoisomerase
Vaccinia DNA topoisomerase forms a covalent DNA-(3′-phosphotyrosyl)-enzyme intermediate at a specific target site 5′-C+5C+4C+3T… 
2003
2003
Biochemical Characterization of an Exonuclease from Arabidopsis thaliana Reveals Similarities to the DNA Exonuclease of the Human Werner Syndrome Protein*
The human Werner syndrome protein (hWRN-p) possessing DNA helicase and exonuclease activities is essential for genome stability… 
2002
2002
The effect of DNA damage on the formation of protein/DNA complexes.
2002
2002
Influence of an 8-oxoadenine lesion on the structural and dynamic features of a 30-mer DNA fragment with and without a mismatch
Purpose : To elucidate the influence of the oxidative lesion 7,8-dihydro-8-oxoadenine (8-oxoA) on the structural and dynamic… 
1999
1999
6-Methoxy-7-methyl-8-oxoguanine, an unusual purine from the ascidian Symplegma rubra.
A new purine derivative, 6-methoxy-7-methyl-8-oxoguanine (1), along with 8-oxoadenine (2) and the human metabolite 3… 
Highly Cited
1993
Highly Cited
1993
Enhancement by L-histidine of nickel(II)-induced DNA-protein cross-linking and oxidative DNA base damage in the rat kidney.
Formation of DNA-protein cross-links and oxidatively damaged DNA bases was investigated with the use of alkaline elution and gas… 
Highly Cited
1992
Highly Cited
1992
Recognition of a guanine-cytosine base pair by 8-oxoadenine.
Two oligodeoxyribonucleotides, d-CTTCTTTTTTATTTT, I(A), and d-ATTATTTTTTATTTT, II(A), where C is 5-methylcytosine and A is 8… 
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