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8-hydroxyadenine

Known as: 7,8-DHOA, 7,8-dihydro-8-oxoadenine 
National Institutes of Health

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Related topics

3 relations

Narrower (1)

8-oxoadenine

Broader (1)

Adenine
analogs & derivatives

Papers overview

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Highly Cited
1999
Highly Cited
1999
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or…
Highly Cited
1996
Highly Cited
1996
Damage, Repair, and Mutagenesis in Nuclear Genes after Mouse Forebrain Ischemia–Reperfusion
To determine whether oxidative stress after cerebral ischemia–reperfusion affects genetic stability in the brain, we studied… 
Highly Cited
1995
Highly Cited
1995
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
1993
1993
7,8-Dihydro-8-oxoadenine as a replacement for cytosine in the third strand of triple helices. Triplex formation without hypochromicity.
Oligonucleotides containing thymine and cytosine (or 5-methylcytosine) bases are known to bind to specific homopurine sequences… 
1992
1992
DNA strand cleavage at 8-hydroxyguanine residues by hot piperidine treatment.
Highly Cited
1991
Highly Cited
1991
An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA.
Highly Cited
1991
Highly Cited
1991
Structure and in vitro replication of DNA templates containing 7,8-dihydro-8-oxoadenine.
Adenine residues in DNA are oxidized under the action of ionizing radiation at the C-8 position to give 7,8-dihydro-8-oxoadenine… 
Highly Cited
1982
Highly Cited
1982
Radioimmunoassay of 7,8-dihydro-8-oxoadenine (8-hydroxyadenine).
SummaryA sensitive and specific radioimmunoassay for 8-hydroxyadenine has been developed. As little as 4 × 10−14 moles of 8… 
Highly Cited
1980
Highly Cited
1980
In vitro gamma irradiation of DNA: identification of radioinduced chemical modifications of the adenine moiety.
Escherichia coli DNA, selectively labeled with /sup 14/C in the adenine moiety, was subjected in aqueous aerated solution to the… 
1968
1968
Chemical analysis of DNA alterations. 3. Isolation and characterization of adenine oxidation products obtained from oligo- and monodeoxyadenylic acids treated with hydroxyl radicals.
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