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7-chlorokynurenate

National Institutes of Health

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7-chlorokynurenic acid

Papers overview

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2005
2005
In Situ–Produced 7‐Chlorokynurenate Has Different Effects on Evoked Responses in Rats with Limbic Epilepsy in Comparison to Naive Controls
Summary:  Purpose: Uncontrolled epilepsy remains a significant health concern and requires new approaches to therapy. N‐methyl‐d… 
2000
2000
In Situ Produced 7-Chlorokynurenate Provides Protection against Quinolinate- and Malonate-Induced Neurotoxicity in the Rat Striatum
Excitotoxic mechanisms may play a critical role in the pathophysiology of several neurological and psychiatric diseases… 
Highly Cited
1998
Highly Cited
1998
Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist.
Single-unit recordings were made in the intact anesthetized rat of the responses of dorsal horn neurons to C-, Adelta-, and Abeta… 
1995
1995
Amygdala N-methyl-d-aspartate receptors participate in the induction of long-term potentiation in the dentate gyrus in vivo
1995
1995
Pharmacological heterogeneity of NMDA receptors in cerebellar granule cells in immature rat slices. A microfluorimetric study with the [Ca2+]i sensitive dye indo-1
1993
1993
The neurotoxicity of sulfur-containing amino acids in energy-deprived rat hippocampal slices
1992
1992
Developmental differences in antagonism of NMDA toxicity by the polyamine site antagonist ifenprodil.
1991
1991
Glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex
1990
1990
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons
Highly Cited
1990
Highly Cited
1990
Reduction of NMDA receptors with dithiothreitol increases [3H]‐MK‐801 binding and NMDA‐induced Ca2+ fluxes
1 We have investigated the modulation of N‐methyl‐d‐aspartate (NMDA) receptor activation by the sulphydryl redox reagents… 
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