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- Publications
- Influence
A Glycine Site Associated with N‐Methyl‐d‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists
- M. Kessler, T. Terramani, G. Lynch, M. Baudry
- Chemistry, Medicine
- Journal of neurochemistry
- 1 April 1989
Abstract Membranes from rat telencephalon contain a single class of strychnine‐insensitive glycine sites. That these sites are associated with N‐methyl‐d‐aspartic acid (NMDA) receptors is indicated… Expand
A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of D-glucose and choline…
- M. Kessler, O. Acuto, C. Storelli, H. Murer, M. Mueller, G. Semenza
- Chemistry, Medicine
- Biochimica et biophysica acta
- 4 January 1978
We have worked out a simplification of the procedure described by Schmitz et al. (Biochim. Biophys. Acta (1973) 323, 98--112) for the preparation of brush border membranes from small intestine. The… Expand
Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior.
- A. Arai, M. Kessler
- Chemistry, Medicine
- Current drug targets
- 1 May 2007
Ampakines are drugs structurally derived from aniracetam that potentiate currents mediated by AMPA type glutamate receptors. These drugs slow deactivation and attenuate desensitization of AMPA… Expand
Quinoxaline derivatives are high-affinity antagonists of the NMDA receptor-associated glycine sites
- M. Kessler, M. Baudry, G. Lynch
- Chemistry, Medicine
- Brain Research
- 12 June 1989
Membranes from rat telencephalon contain strychnine-insensitive glycine binding sites associated with NMDA receptors. Three quinoxaline derivatives, among them the high-affinity AMPA receptor… Expand
The effects of adenosine on the development of long-term potentiation
- A. Arai, M. Kessler, G. Lynch
- Biology, Medicine
- Neuroscience Letters
- 30 October 1990
In previous work we found that a brief period of hypoxia occurring within 1-2 min of high-frequency stimulation disrupts the development of long-term potentiation (LTP) in the CA1 field of rat… Expand
Biochemistry of the Na+, D-glucose cotransporter of the small-intestinal brush-border membrane. The state of the art in 1984.
- G. Semenza, M. Kessler, M. Hosang, J. Weber, U. Schmidt
- Chemistry, Medicine
- Biochimica et biophysica acta
- 3 September 1984
Stable maintenance of glutamate receptors and other synaptic components in long‐term hippocampal slices
- B. Bahr, M. Kessler, +5 authors K. B. Hoffman
- Chemistry, Medicine
- Hippocampus
- 1995
Cultured hippocampal slices retain many in vivo features with regard to circuitry, synaptic plasticity, and pathological responsiveness, while remaining accessible to a variety of experimental… Expand
Effect of cyclothiazide on binding properties of AMPA-type glutamate receptors: lack of competition between cyclothiazide and GYKI 52466.
- M. Kessler, A. Arai, A. Quan, G. Lynch
- Chemistry, Medicine
- Molecular pharmacology
- 1996
The effects of cyclothiazide on the properties of (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors were studied using equilibrium binding techniques and… Expand
Phlorizin as a probe of the small-intestinal Na+,D-glucose cotransporter. A model.
- G. Toggenburger, M. Kessler, G. Semenza
- Chemistry, Medicine
- Biochimica et biophysica acta
- 14 June 1982
(1)'Uptake' of phlorizin by intestinal brush border membrane vesicles is stimulated, much as that of D-glucose, by the simultaneous presence of Naout+ and delta psi much less than 0. However,… Expand
Benzamide-Type AMPA Receptor Modulators Form Two Subfamilies with Distinct Modes of Action
- A. Arai, Yan-Fang Xia, G. Rogers, G. Lynch, M. Kessler
- Biology, Medicine
- Journal of Pharmacology and Experimental…
- 1 December 2002
CX516 (BDP-12) and CX546, two first-generation benzamide-type AMPA receptor modulators, were compared with regard to their influence on AMPA receptor-mediated currents, autaptic responses in cultured… Expand