M. Kessler

Publications102
h-index37
Citations5,055
Highly Influential Citations124
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A Glycine Site Associated with N‐Methyl‐d‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists
Abstract Membranes from rat telencephalon contain a single class of strychnine‐insensitive glycine sites. That these sites are associated with N‐methyl‐d‐aspartic acid (NMDA) receptors is indicated… Expand
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A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of D-glucose and choline…
We have worked out a simplification of the procedure described by Schmitz et al. (Biochim. Biophys. Acta (1973) 323, 98--112) for the preparation of brush border membranes from small intestine. The… Expand
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Pharmacology of ampakine modulators: from AMPA receptors to synapses and behavior.
Ampakines are drugs structurally derived from aniracetam that potentiate currents mediated by AMPA type glutamate receptors. These drugs slow deactivation and attenuate desensitization of AMPA… Expand
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Quinoxaline derivatives are high-affinity antagonists of the NMDA receptor-associated glycine sites
Membranes from rat telencephalon contain strychnine-insensitive glycine binding sites associated with NMDA receptors. Three quinoxaline derivatives, among them the high-affinity AMPA receptor… Expand
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The effects of adenosine on the development of long-term potentiation
In previous work we found that a brief period of hypoxia occurring within 1-2 min of high-frequency stimulation disrupts the development of long-term potentiation (LTP) in the CA1 field of rat… Expand
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Biochemistry of the Na+, D-glucose cotransporter of the small-intestinal brush-border membrane. The state of the art in 1984.
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Stable maintenance of glutamate receptors and other synaptic components in long‐term hippocampal slices
Cultured hippocampal slices retain many in vivo features with regard to circuitry, synaptic plasticity, and pathological responsiveness, while remaining accessible to a variety of experimental… Expand
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Effect of cyclothiazide on binding properties of AMPA-type glutamate receptors: lack of competition between cyclothiazide and GYKI 52466.
The effects of cyclothiazide on the properties of (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors were studied using equilibrium binding techniques and… Expand
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Phlorizin as a probe of the small-intestinal Na+,D-glucose cotransporter. A model.
(1)'Uptake' of phlorizin by intestinal brush border membrane vesicles is stimulated, much as that of D-glucose, by the simultaneous presence of Naout+ and delta psi much less than 0. However,… Expand
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Benzamide-Type AMPA Receptor Modulators Form Two Subfamilies with Distinct Modes of Action
CX516 (BDP-12) and CX546, two first-generation benzamide-type AMPA receptor modulators, were compared with regard to their influence on AMPA receptor-mediated currents, autaptic responses in cultured… Expand
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